Lee Jeong-woo
Kyung Hee University · 医学
研究室紹介
Professor Lee Jeong-woo's research lab specializes in the development of advanced functional nanomaterials and innovative drug delivery systems. The lab focuses on designing graphene-based composites for high-performance energy storage applications, such as supercapacitors, and explores nanostructured hydroxides and oxides for enhanced electrochemical performance. Additionally, the lab is actively engaged in the design and translation of microneedle technologies for painless, self-administered delivery of biopharmaceuticals, with a strong emphasis on maintaining bioactivity and safety. The integration of materials science, electrochemistry, and biomedical engineering defines the lab’s interdisciplinary approach.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Graphene/Mn 3 O 4 composites were prepared by a simple hydrothermal process from KMnO 4 using ethylene glycol as a reducing agent. Mn 3 O 4 nanorods of 100 nm to 1 μm length were observed to be well-dispersed on graphene sheets. To assess the properties of these materials for use in supercapacitors, cyclic voltammetry and galvanostatic charging–discharging measurements were performed. Graphene/Mn 3 O 4 composites could be charged and discharged faster and had higher capacitance than free Mn 3 O
Reduced graphene oxide/α-Ni(OH)(2) composites present high electrochemical properties, with specific capacitance of 1215 F g(-1) at 5 mV s(-1) scan rate, since graphene as conductive matrix provides electronic conduction pathway.
The clinical impact of biotechnology has been constrained by the limitations of traditional hypodermic injection of biopharmaceuticals. Microneedle patches have been proposed as a minimally invasive alternative. In this study, the translation of a dissolving microneedle patch designed for simple, painless self-administration of biopharmacetucials that generates no sharp biohazardous waste is assessed. To study the pharmacokinetics and safety of this approach, human growth hormone (hGH) was encap
Hierarchical microspheres composed of wrinkled α-Ni(OH) 2 nanosheets were synthesized from an aqueous solution containing nickel salts, hexamethylenetetramine, 1-butanol, and dodecyl sulfate. The exchange of intercalated dodecyl sulfate anions within the microspheres by smaller anions (Cl –, NO 3 –, OAc –, and SO 4 2– ) resulted in retention of morphology. A possible growth mechanism is proposed based on the observation of the effects the parameter variation (different nickel and hydroxide sourc
BACKGROUND: Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400×10(3) cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process. However, even though PRP is widely used, the mechanism or actual effect is presently unclear. Therefore, this study was performed to investigate the levels of growth factors and platelet concentration rate. METHODS: Autologous blood for preparing PRP wa
A microneedle system has been developed to deliver chemical and biological agents through the stratum corneum, which is the main barrier to drug delivery. Recently, microneedles have been fabricated from various kinds of polymers, including biocompatible polymer, biodegradable polymer, and water-soluble polymer. Polymer microneedles offer the benefits of ease of fabrication, cost-effectiveness, and mass production, as well as controlled drug release using the water solubility and degradation pro
The environments that harbor hematopoietic stem and progenitor cells are critical to explore for a better understanding of hematopoiesis during health and disease. These compartments often are inaccessible for controlled and rapid experimentation, thus limiting studies to the evaluation of conventional cell culture and transgenic animal models. Here we describe the manufacture and image-guided monitoring of an engineered microenvironment with user-defined properties that recruits hematopoietic p
KEYWORDS: Microneedle patchtransdermal drug deliverytopical drug deliverytargeted drug deliveryocularoralvaginalfingernailvascular endothelium
This study demonstrates the nature progression of CM and quantifies the clinical characteristics of hypertrophy and nodule formation with untreated head and neck CM. Early and continuous treatment is recommended in hopes of preventing CM progression.