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Mingoo Kim

Yonsei University · 工学

研究室紹介

Professor Mingoo Kim's research lab specializes in computational and systems biology, with a focus on reproductive immunology and gene regulation in swine, particularly the molecular mechanisms underlying embryo implantation and pregnancy maintenance. The lab also conducts advanced research in coding theory and error control in communication systems, emphasizing the design and analysis of convolutional and BCH codes for reliable data transmission. Their interdisciplinary work bridges life sciences and engineering, integrating genomics, bioinformatics, and mathematical modeling to address challenges in both biological systems and information technology. The lab applies high-throughput omics technologies and statistical methods to uncover gene expression networks and system-level vulnerabilities in complex biological and engineered systems.

reproductive immunologygene expression profilingconvolutional codeserror control codingvulnerability assessment

Research Overview

Papers
103
Total Citations
1,651
Papers (5y)
16
Primary Field
工学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
16total
2020
2021
2022
2023
2024
Citations per year (5y)
98total
20202021202220232024

Selected Papers

15
1
Article|46 citations·2011
Swine Leukocyte Antigen-DQ Expression and Its Regulation by Interferon-Gamma at the Maternal-Fetal Interface in Pigs1
Mingoo Kim, Heewon Seo, Yohan Choi, Jangsoo Shim, Fuller W. Bazer, Hakhyun Ka
SJR Q1Biology of ReproductionOA

Successful pregnancy requires an appropriate intrauterine immune response to the conceptus, which is a semiallograft within the uterus. We reported that swine leukocyte antigen-DQA (SLA-DQA), a major histocompatibility complex (MHC) class II gene, is expressed in the uterine endometrium at the time of conceptus implantation in pigs. Because MHC molecules play critical roles in the immune system, SLA-DQ was hypothesized to be involved in immune regulation during pregnancy. Therefore, we examined

ImmunologyImmunology and Microbiology
2
Article|33 citations·1996
Undetected error probabilities of binary primitive BCH codes for both error correction and detection
Mingoo Kim, Jae Lee
SJR Q1IEEE Transactions on Communications

We investigate the undetected error probabilities for bounded-distance decoding of binary primitive BCH codes when they are used for both error correction and detection on a binary symmetric channel. We show that the undetected error probability of binary linear codes can be simplified and quantified if the weight distribution of the code is binomial-like. We obtain bounds on the undetected error probability of binary primitive BCH codes by applying the result to the code and show that the bound

Artificial IntelligenceComputer Science
3
Article|30 citations·2012
Microarray Analysis of Gene Expression in the Uterine Endometrium during the Implantation Period in Pigs
Mingoo Kim, Heewon Seo, Yohan Choi, Jangsoo Shim, Heebal Kim, Chang‐Kyu Lee, Hakhyun Ka
Asian-Australasian Journal of Animal SciencesOA

During embryo implantation in pigs, the uterine endometrium undergoes dramatic morphological and functional changes accompanied with dynamic gene expression. Since the greatest amount of embryonic losses occur during this period, it is essential to understand the expression and function of genes in the uterine endometrium. Although many reports have studied gene expression in the uterine endometrium during the estrous cycle and pregnancy, the pattern of global gene expression in the uterine endo

ImmunologyImmunology and Microbiology
4
Article|27 citations·2015
Analysis of Stage-Specific Gene Expression Profiles in the Uterine Endometrium during Pregnancy in Pigs
Mingoo Kim, Heewon Seo, Yohan Choi, Inkyu Yoo, Minseok Seo, Chang‐Kyu Lee, Heebal Kim, Hakhyun Ka
SJR Q1PLoS ONEOA

The uterine endometrium plays a critical role in regulating the estrous cycle and the establishment and maintenance of pregnancy in mammalian species. Many studies have investigated the expression and function of genes in the uterine endometrium, but the global expression pattern of genes and relationships among genes differentially expressed in the uterine endometrium during gestation in pigs remain unclear. Thus, this study investigated global gene expression profiles using microarray in pigs.

ImmunologyImmunology and Microbiology
5
Article|25 citations·1997
On systematic punctured convolutional codes
Mingoo Kim
SJR Q1IEEE Transactions on Communications

This paper investigates high rate systematic punctured convolutional codes based on Forney's (1970) results. High rate systematic punctured convolutional codes of rate-2/3 with constraint length 3/spl les/K/spl les/7 and rate-3/4 through 15/16 with K=7 are derived using the rate-1/2 best known nonsystematic convolutional codes. Weight spectra of newly discovered systematic punctured convolutional codes are provided and compared with the best known nonsystematic punctured codes. Simulation result

Electrical and Electronic EngineeringEngineering
6
Article|18 citations·2008
Aberrant expression of retinol-binding protein, osteopontin and fibroblast growth factor 7 in the porcine uterine endometrium of pregnant recipients carrying embryos produced by somatic cell nuclear transfer
Mingoo Kim, Heewon Seo, Yohan Choi, Woo Suk Hwang, Chang‐Kyu Lee, Hakhyun Ka
SJR Q1Animal Reproduction Science
Public Health, Environmental and Occupational HealthMedicine
7
Article|15 citations·2006
Vulnerability Indices For Power Systems
Mingoo Kim, M.A. El-Sharkawi, Robert J. Marks

The purpose of vulnerability assessment is to determine when a disruption of service is likely to occur and to take steps to reduce the associated risk. With the growth of power systems, increases in grid complexity, and the trend toward deregulation, vulnerability assessment is imperative. Accurate vulnerability assessment is especially vital during heavy loading conditions and a vulnerability index is greatly needed to help the operator steer the system to viable conditions. In this paper, two

Electrical and Electronic EngineeringEngineering
8
Article|14 citations·2009
Mixture-model based estimation of gene expression variance from public database improves identification of differentially expressed genes in small sized microarray data
Mingoo Kim, Sung Bum Cho, Ju Han Kim
SJR Q1BioinformaticsOA

MOTIVATION: The small number of samples in many microarray experiments is a challenge for the correct identification of differentially expressed gens (DEGs) by conventional statistical means. Information from public microarray databases can help more efficient identification of DEGs. To model various experimental conditions of a public microarray database, we applied Gaussian mixture model and extracted bi- or tri-modal distributions of gene expression. Prior variance of Baldi's Bayesian framewo

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|12 citations·2002
Performance comparison of detection methods in magneto-optical disc system with (1, 7) RLL code
Mingoo Kim, Kwang Man Ok, Jae Hong Lee

The performance of detection methods is analyzed in the magneto-optical disc (MOD) system with (1,7) runlength limited (RLL) code. The peak detection, threshold detection, and partial response channel with maximum likelihood (PRML) detection are considered. The MOD system uses an SHG green laser and has a storage capacity of 4.2 Gbyte. The channel model is based on the implemented MOD system. The bit error probabilities of each detection method are obtained from simulation for three cases of onl

Computational Theory and MathematicsComputer Science
10
Article|10 citations·2011
Extracting regulatory modules from gene expression data by sequential pattern mining
Mingoo Kim, Hyunjung Shin, Tae Su Chung, Je‐Gun Joung, Ju Han Kim
SJR Q1BMC GenomicsOA

BACKGROUND: Identifying a regulatory module (RM), a bi-set of co-regulated genes and co-regulating conditions (or samples), has been an important challenge in functional genomics and bioinformatics. Given a microarray gene-expression matrix, biclustering has been the most common method for extracting RMs. Among biclustering methods, order-preserving biclustering by a sequential pattern mining technique has native advantage over the conventional biclustering approaches since it preserves the orde

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
Article|9 citations·2018
Effects of ZrN and W Particle Sizes on the Mechanical and Ablation Properties of ZrN/W Composites
Mingoo Kim, Seulgi Kim, Jiyeon Kang, Sung Ho Song, Dongju Lee
SJR Q1Metals and Materials International
Mechanical EngineeringEngineering
12
Book Chapter|5 citations·2006
Feature Reduction Techniques for Power System Security Assessment
Mingoo Kim, Sung‐Kwan Joo
SJR Q2Lecture notes in computer science
Electrical and Electronic EngineeringEngineering
13
Article|4 citations·1996
Decoder Error Probability of Binary Linear Block Codes and Its Application to Binary Primitive BCH Codes
Mingoo Kim, Jae Hong Lee
SJR Q3IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences
Electrical and Electronic EngineeringEngineering
14
Article|4 citations·2002
Application of computational intelligence to power system vulnerability assessment and adaptive protection using high-speed communication
Mingoo Kim, M.A. El-Sharkawi
Control and Systems EngineeringEngineering
15
Article|3 citations·2011
Activated Leukocyte Cell Adhesion Molecule: Expression in the Uterine Endometrium during the Estrous Cycle and Pregnancy in Pigs
Mingoo Kim, Jangsoo Shim, Heewon Seo, Yohan Choi, Chang‐Kyu Lee, Hakhyun Ka
Asian-Australasian Journal of Animal SciencesOA

The pig exhibits true epitheliochorial placentation, where the fetal membrane maintains attachment throughout pregnancy but does not invade into the maternal uterine endometrium. Accordingly, the expression and function of cell adhesion molecules are very important for embryo implantation and the establishment of pregnancy. In our recent microarray analysis, we found that activated leukocyte cell adhesion molecule (ALCAM) was expressed in the uterine endometrium during pregnancy in pigs. To bett

ImmunologyImmunology and Microbiology

Research Areas

Electrical and Electronic EngineeringAgronomy and Crop ScienceMolecular BiologyImmunologyOrganic ChemistryFood Science

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