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Myung Jae Jeon

Seoul National University · 医学

研究室紹介

Professor Myung Jae Jeon's research lab specializes in female pelvic floor disorders, with a focus on the pathophysiology, risk factors, and molecular mechanisms underlying pelvic organ prolapse (POP) and female sexual dysfunction (FSD). The lab investigates the roles of genetic factors—such as COL3A1 and HOXA11 gene polymorphisms and miRNA regulation—in connective tissue integrity and pelvic support. It also explores the impact of systemic conditions like metabolic syndrome and menopause-related hormonal changes on sexual and pelvic health in women. The research integrates clinical epidemiology, molecular biology, and translational medicine to identify biomarkers and potential therapeutic targets.

pelvic organ prolapsefemale sexual dysfunctionHOXA11miRNA regulationmetabolic syndrome

Research Overview

Papers
108
Total Citations
1,778
Papers (5y)
25
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
25total
2021
2022
2023
2024
2025
Citations per year (5y)
120total
20212022202320242025

Selected Papers

15
1
Article|93 citations·2008
Comparison of the treatment outcome of pubovaginal sling, tension-free vaginal tape, and transobturator tape for stress urinary incontinence with intrinsic sphincter deficiency
Myung Jae Jeon, Hyun-Joo Jung, Sue-Min Chung, Sei-Kwang Kim, Sang Wook Bai
SJR Q1American Journal of Obstetrics and GynecologyOA
RheumatologyMedicine
2
Article|59 citations·2015
Risk factors for negative impacts on sexual activity and function in younger breast cancer survivors
Maria Lee, Yun Hwan Kim, Myung Jae Jeon
SJR Q1Psycho-Oncology

Chemo-related menopause was significantly associated with both sexual inactivity and dysfunction after treatment. Thyroid dysfunction and depression were risk factors for sexual inactivity in younger breast cancer survivors.

OncologyMedicine
3
Article|39 citations·2008
Risk Factors for the Recurrence of Pelvic Organ Prolapse
Myung Jae Jeon, Sue Min Chung, Hyun Joo Jung, Sei Kwang Kim, Sang Wook Bai
SJR Q2Gynecologic and Obstetric InvestigationOA

BACKGROUND/AIMS: To investigate the risk factors for the recurrence of prolapse after traditional pelvic reconstructive surgery. METHODS: The medical records of 212 patients who received traditional restorative reconstructive surgeries for symptomatic pelvic organ prolapse from March 1999 to April 2006 were retrospectively analyzed. Recurrence was defined as any prolapse of stage II or greater according to the Pelvic Organ Prolapse Quantification system. The log-rank test and Cox regression of t

RheumatologyMedicine
4
Article|38 citations·2011
Does Metabolic Syndrome Impair Sexual Function in Middle- to Old-Aged Women?
Yun Hwan Kim, Sun Mie Kim, Jinju Kim, In Seong Cho, Myung Jae Jeon
SJR Q1The Journal of Sexual Medicine

INTRODUCTION: To date, there are few studies dealing with the impact of metabolic syndrome (MS) on female sexual function, and the association between MS and female sexual dysfunction (FSD) in middle- to old-aged women remains unclear. AIM: To evaluate the impact of MS on sexual function in middle- to old-aged women. METHODS: From May 2009 to January 2010, we performed a cross-sectional study of sexually active women (≥ 40 years old) who visited a health-screening clinic. Comprehensive history t

Psychiatry and Mental healthMedicine
5
Article|29 citations·2009
The Relationship Between COL3A1 Exon 31 Polymorphism and Pelvic Organ Prolapse
Myung Jae Jeon, Sue Min Chung, Jong Rak Choi, Hyun Joo Jung, Sei Kwang Kim, Sang Wook Bai
SJR Q1The Journal of UrologyOA

COL3A1 exon 31 polymorphism may have a role in determining the risk of pelvic organ prolapse in women with risk factors such as aging, vaginal childbirth and hypoestrogenism.

RheumatologyMedicine
6
Article|29 citations·2009
A Long-Term Treatment Outcome of Abdominal Sacrocolpopexy
Myung Jae Jeon, Yeo Jung Moon, Hyun Joo Jung, Kyung Jin Lim, Hyo In Yang, Sei Kwang Kim, Sang Wook Bai
SJR Q2Yonsei Medical JournalOA

ASC provides durable pelvic support, however, it may be ineffective for alleviating pelvic floor dysfunction except for urinary urgency and voiding dysfunction, and it contains major complication risk that cannot be overlooked.

RheumatologyMedicine
7
Article|28 citations·2015
MicroRNA‐30d and microRNA‐181a regulate HOXA11 expression in the uterosacral ligaments and are overexpressed in pelvic organ prolapse
Myung Jae Jeon, Eun Jae Kim, Maria Lee, Hoguen Kim, Jong Rak Choi, Hee Dong Chae, Yeo Jung Moon, Sei Kwang Kim, Sang Wook Bai
SJR Q2Journal of Cellular and Molecular MedicineOA

The balanced turnover of collagen is necessary to maintain the mechanical strength of pelvic supportive connective tissues. Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling may contribute to alterations in the biochemical strength of the USLs, leading to pelvic organ prolapse (POP). However, it is unknown how HOXA11 transcripts are regulated in the USLs. In this study, we

RheumatologyMedicine
8
Article|25 citations·2007
Is hysterectomy or the use of graft necessary for the reconstructive surgery for uterine prolapse?
Myung Jae Jeon, Hyun Joo Jung, Hyun Jung Choi, Sei Kwang Kim, Sang Wook Bai
SJR Q2International Urogynecology JournalOA
RheumatologyMedicine
9
Article|23 citations·2011
Association between metabolic syndrome and pelvic floor dysfunction in middle-aged to older Korean women
Yun Hwan Kim, Jinju Kim, Sun Mie Kim, Yunhee Choi, Myung Jae Jeon
SJR Q1American Journal of Obstetrics and Gynecology
RheumatologyMedicine
10
Article|22 citations·2019
The effect of diagnosis-related group payment system on the quality of medical care for pelvic organ prolapse in Korean tertiary hospitals
Myung Jae Jeon, Sung Pil Choo, Young Hwa Kwak, Dong Wook Kim, Eui Hyeok Kim
SJR Q1PLoS ONEOA

The implementation of DRG in Korean tertiary hospitals has led to increase of outpatient visits and reduced surgical management for POP, which indicates that the uniform application of DRG influences the quality of care for POP patients.

RheumatologyMedicine
11
Review|18 citations·2019
Surgical decision making for symptomatic pelvic organ prolapse: evidence-based approach
Myung Jae Jeon
SJR Q2Obstetrics & Gynecology ScienceOA

Surgery is the mainstay of treatment for symptomatic pelvic organ prolapse (POP), and a variety of procedures can be performed to correct POP. When deciding on the proper surgical procedure, the surgeon must take into consideration the individual patient's risk for surgical complication and prolapse recurrence and her preference. This review will discuss the key issues faced in the surgical decision-making process for POP and recommendations based on the current scientific evidence.

RheumatologyMedicine
12
Article|18 citations·2009
A Long-Term Treatment Outcome of Abdominal Sacrocolpopexy
전명재, Yeo Jung Moon, Hyun Joo Jung, Kyung Jin Lim, Hyo In Yang, Sei Kwang Kim, Sang Wook Bai
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120090500060807

Purpose: The aim of this study was to evaluate the long-term treatment outcome and major complication rates of abdominal sacrocolpopexy (ASC). Materials and Methods: This retrospective study included 57 Korean women who underwent ASC with mesh for symptomatic uterine or vault prolapse and attended follow-up visits for at least 5 years. Forty-seven women with urodynamic stress incontinence concomitantly received a modified Burch colposuspension. The long-term anatomical and functional outcomes an

13
Article|16 citations·2020
Risk factors for vaginal mesh erosion after sacrocolpopexy in Korean women
Tae Yeon Kim, Myung Jae Jeon
SJR Q1PLoS ONEOA

Premenopausal or menopausal women on ERT are at high risk for mesh erosion after SCP with type 1 polypropylene mesh, and two-thirds of mesh erosion cases require reoperation. This information should be incorporated into patient counseling and treatment decisions.

RheumatologyMedicine
14
Article|15 citations·2014
Two-year urinary outcomes of sacrocolpopexy with or without transobturator tape: results of a prolapse-reduction stress test-based approach
Myung Jae Jeon, Ji Young Kim, Yeo Jung Moon, Sang Wook Bai, Eun‐Hee Yoo
SJR Q2International Urogynecology JournalOA
RheumatologyMedicine
15
Article|15 citations·2021
Development and validation of a prediction model for bothersome stress urinary incontinence after prolapse surgery: A retrospective cohort study
Sumin Oh, Sungyoung Lee, Woo Yeon Hwang, Dong Hoon Suh, Myung Jae Jeon
SJR Q1BJOG An International Journal of Obstetrics & Gynaecology

OBJECTIVE: To develop and validate a prediction model for bothersome stress urinary incontinence after prolapse surgery and to compare it with an existing clinical prediction model (CUPIDO model). DESIGN: Retrospective cohort study. SETTING: Two tertiary hospitals in South Korea. POPULATION: A total of 1142 patients who underwent prolapse surgery with or without a concomitant midurethral sling. METHODS: To construct a prediction model, we performed logistic regression using both exhaustive and s

RheumatologyMedicine

Research Areas

RheumatologyReproductive MedicineSurgeryPublic Health, Environmental and Occupational HealthEpidemiologyObstetrics and Gynecology

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