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Oh-hyun Lee

Yonsei University · 医学

研究室紹介

Professor Oh-hyun Lee's research lab specializes in interventional cardiology, with a primary focus on radial artery access techniques for percutaneous coronary interventions (PCI), particularly the distal radial approach (DRA). The lab investigates procedural feasibility, spasm prevention strategies, and outcomes in acute coronary syndromes such as ST-elevation myocardial infarction (STEMI). Additional research extends to left atrial appendage occlusion and patent foramen ovale (PFO) closure, emphasizing neurological outcomes and optimal patient selection in stroke prevention. The lab integrates clinical outcomes with procedural innovation and medication optimization to improve vascular access safety and efficacy.

percutaneous coronary interventiondistal radial accessstroke preventionleft atrial appendage occlusionradial artery spasm

Research Overview

Papers
76
Total Citations
908
Papers (5y)
35
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
35total
2022
2023
2024
2025
2026
Citations per year (5y)
176total
20222023202420252026

Selected Papers

15
1
Article|32 citations·2018
Feasibility of Left Atrial Appendage Occlusion for Left Atrial Appendage Thrombus in Patients With Persistent Atrial Fibrillation
Oh‐Hyun Lee, Jung‐Sun Kim, Hui‐Nam Pak, Geu‐Ru Hong, Chi Young Shim, Jae‐Sun Uhm, In‐Jeong Cho, Boyoung Joung, Cheol Woong Yu, Hyun‐Jong Lee, Woong Chol Kang, Eun‐Seok Shin
SJR Q2The American Journal of CardiologyOA
Cardiology and Cardiovascular MedicineMedicine
2
Article|15 citations·2021
Comparison of Distal Radial, Proximal Radial, and Femoral Access in Patients with ST-Elevation Myocardial Infarction
Oh‐Hyun Lee, Yongcheol Kim, Nak‐Hoon Son, Ji Woong Roh, Eui Im, Deok‐Kyu Cho, Donghoon Choi
SJR Q1Journal of Clinical MedicineOA

Recent studies have indicated that distal radial access (DRA) is feasible in patients undergoing percutaneous coronary intervention (PCI). The present study aimed to compare DRA, proximal radial access (PRA), and femoral access (FA) in patients with ST-elevation myocardial infarction (STEMI) undergoing PCI. Data were analyzed for 109 patients with STEMI treated via primary PCI from March 2020 to May 2021. The success rate of DRA was 83.3% (35/42), including seven cases of failed puncture (punctu

Pulmonary and Respiratory MedicineMedicine
3
Article|14 citations·2021
Feasibility and Safety of the Left Distal Radial Approach in Percutaneous Coronary Intervention for Bifurcation Lesions
Oh‐Hyun Lee, Ji Woong Roh, Eui Im, Deok‐Kyu Cho, Myung Ho Jeong, Donghoon Choi, Yongcheol Kim
SJR Q1Journal of Clinical MedicineOA

Recently, the left distal radial approach (DRA) for percutaneous coronary intervention (PCI) has been shown to be a feasible option, but there are limited data regarding the feasibility of performing bifurcation PCI via the left DRA. Therefore, this study aimed to describe our experience with the contemporary left DRA to perform PCI of bifurcation lesions. Between December 2017 and December 2019, we identified 106 patients treated with bifurcation PCI via the left DRA. We evaluated the success r

Pulmonary and Respiratory MedicineMedicine
4
Article|11 citations·2018
Peripheral artery disease is associated with poor clinical outcome in patients with abdominal aortic aneurysm after endovascular aneurysm repair
Oh‐Hyun Lee, Young‐Guk Ko, Chul‐Min Ahn, Dong‐Ho Shin, Jung‐Sun Kim, Byeong‐Keuk Kim, Donghoon Choi, Do Yun Lee, Myeong‐Ki Hong, Yangsoo Jang
SJR Q1International Journal of CardiologyOA
Pulmonary and Respiratory MedicineMedicine
5
Article|10 citations·2023
Comparison of spasmolytic regimen for prevention of radial artery spasm during the distal radial approach: A single-center, randomized study
Oh‐Hyun Lee, Ji Woong Roh, Yongcheol Kim, Nak‐Hoon Son, Jay Yi Cho, Daesek Jang, Eui Im, Deok‐Kyu Cho, Donghoon Choi
SJR Q1Frontiers in Cardiovascular MedicineOA

Background The distal radial approach (DRA) for coronary catheterization is increasingly being used worldwide yet the optimal medication regimen to prevent radial artery spasm (RAS), an important factor for the success of the procedure, remains unclear. The aim of this study is to examine the effectiveness of medication for preventing RAS via the DRA. Methods This was a prospective, comparative randomized study including 400 patients who underwent coronary catheterization via DRA in single cente

Pulmonary and Respiratory MedicineMedicine
6
Article|9 citations·2021
Percutaneous Left Atrial Appendage Occlusion Yields Favorable Neurological Outcomes in Patients with Non-Valvular Atrial Fibrillation
Oh‐Hyun Lee, Young Dae Kim, Jung‐Sun Kim, Nak‐Hoon Son, Hui‐Nam Pak, Boyoung Joung, Cheol Woong Yu, Hyun‐Jong Lee, Woong Chol Kang, Eun‐Seok Shin, Rak Kyeong Choi, Do‐Sun Lim
SJR Q2Korean Circulation JournalOA

Percutaneous LAAO was associated with more favorable neurological outcomes after ischemic cerebrovascular event than NOAC treatment.

Cardiology and Cardiovascular MedicineMedicine
7
Article|7 citations·2018
Favorable neurological outcome after ischemic cerebrovascular events in patients treated with percutaneous left atrial appendage occlusion compared with warfarin
Oh‐Hyun Lee, Young Dae Kim, Jung‐Sun Kim, Hui‐Nam Pak, Geu‐Ru Hong, Chi Young Shim, Jae‐Sun Uhm, In‐Jeong Cho, Boyoung Joung, Sung‐Jin Hong, Chul‐Min Ahn, Byeong‐Keuk Kim
SJR Q1Catheterization and Cardiovascular InterventionsOA

OBJECTIVES: This study sought to investigate neurological disability after ischemic cerebrovascular events in patients treated with left atrial appendage (LAA) occlusion compared with those on warfarin. BACKGROUND: Prior studies demonstrated that cerebrovascular events after LAA occlusion in patients with nonvalvular atrial fibrillation (NVAF) is largely nondisabling. METHODS: From the 1,189 patients in the Korean LAA Occlusion and European Amplatzer Cardiac Plug Multi-Center Registry, 24 patien

Cardiology and Cardiovascular MedicineMedicine
8
Article|7 citations·2015
Anomalous Origin of the Left Circumflex Artery from the Right Sinus of Valsalva: Non-ST-segment Elevation Myocardial Infarction
Oh‐Hyun Lee, Gwang Seok Yoon, Seong Huan Choi, Hyun Ik Shim, Yong‐Soo Baek, Sung‐Hee Shin, Dae‐Hyeok Kim, Seong‐Ill Woo, Sang‐Don Park
SJR Q3Internal MedicineOA

An anomalous origin of the left coronary artery from the right sinus of Valsalva (RSV) is rare. We herein report the case of an 80-year-old woman who presented to the emergency department with chest pain. Emergent coronary angiography was performed following a diagnosis of non-ST segment elevation myocardial infarction. A right coronary angiogram showed that the common trunk originating from the RSV branched into the left anterior descending and right coronary arteries. Although the initial angi

Pulmonary and Respiratory MedicineMedicine
9
Article|7 citations·2022
Percutaneous Patent Foramen Ovale Closure After Stroke
Oh‐Hyun Lee, Jung‐Sun Kim
SJR Q2Korean Circulation JournalOA

Percutaneous patent foramen ovale (PFO) closure in patients with a prior PFO-associated stroke showed a risk reduction of the stroke recurrence compared to the medical therapy alone in recent several studies. Nevertheless, optimal patient selection for PFO closure has not been clarified. In this paper, we discuss the characteristics of PFO-associated strokes and discuss the recently published evidence and patient selection for PFO closure in patients with ischemic stroke. The lesions characteris

Pulmonary and Respiratory MedicineMedicine
10
Article|6 citations·2019
The Incidence of Non-Cardiac Surgery in Patients Treated With Drug-Eluting Stents According to Age
Oh‐Hyun Lee, Sung‐Jin Hong, Chul‐Min Ahn, Jung‐Sun Kim, Byeong‐Keuk Kim, Young‐Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong‐Ki Hong
SJR Q3˜The œJournal of invasive cardiology/˜The œjournal of invasive cardiology

Non-cardiac surgery with requests for cessation of dual-antiplatelet treatment was frequently performed in patients ≥62 years old who were treated with DES implantation in a real-world clinical practice.

SurgeryMedicine
11
Article|6 citations·2023
Invasive physiologic assessment of coronary artery stenosis by resting full-cycle ratio and fractional flow reserve: a prospective observational study
Oh‐Hyun Lee, Ji Woong Roh, Yongcheol Kim, Seok‐Jae Heo, Eui Im, Deok‐Kyu Cho
SJR Q1Scientific ReportsOA

Resting full-cycle ratio (RFR), an alternative to fractional flow reserve (FFR) for evaluating intermediate coronary artery stenosis, helps reduce patients' time, cost, and discomfort. However, the validation data for RFR and FFR are lacking. We aimed to assess the diagnostic accuracy of RFR and FFR and evaluate effective decision-making for revascularization using their values. Patients subjected to an invasive physiological study for intermediate coronary artery stenosis in Yongin Severance ho

SurgeryMedicine
12
Article|5 citations·2017
Percutaneous isolation of left atrial appendage thrombus
Oh‐Hyun Lee, Jae‐Sun Uhm, Jung‐Sun Kim, In‐Jeong Cho, Geu‐Ru Hong, Hui‐Nam Pak, Yangsoo Jang
SJR Q4Journal of Cardiology CasesOA
Cardiology and Cardiovascular MedicineMedicine
13
Article|5 citations·2024
Intervención coronaria percutánea guiada por tomografía de coherencia óptica frente a guiada por ecografía intravascular en pacientes con infarto agudo de miocardio
Oh‐Hyun Lee, Seok‐Jae Heo, Tom Johnson, Yongcheol Kim, Deok‐Kyu Cho, Jung‐Sun Kim, Byeong‐Keuk Kim, Donghoon Choi, Myeong‐Ki Hong, Yangsoo Jang, Myung Ho Jeong
SJR Q2Revista Española de Cardiología
SurgeryMedicine
14
Article|5 citations·2023
Optical coherence tomography-guided versus intravascular ultrasound-guided percutaneous coronary intervention in patients with acute myocardial infarction
Oh‐Hyun Lee, Seok‐Jae Heo, Tom Johnson, Yongcheol Kim, Deok‐Kyu Cho, Jung‐Sun Kim, Byeong‐Keuk Kim, Donghoon Choi, Myeong‐Ki Hong, Yangsoo Jang, Myung Ho Jeong
SJR Q1Revista Española de Cardiología (English Edition)
SurgeryMedicine
15
Article|5 citations·2014
In vitroAntagonism between Cefotaxime and Anti-Rickettsial Antibiotics againstOrientia tsutsugamushi
Oh‐Hyun Lee, Ji Hyeon Baek, Jin Soo Lee, Moon‐Hyun Chung, Sun Myoung Lee, Jae‐Seung Kang
SJR Q2Infection and ChemotherapyOA

We have investigated the in vitro antimicrobial effects of antibiotic combinations against Orientia tsutsugamushi, the causative agent of scrub typhus. ECV304 cells were infected with the Boryong strain of O. tsutsugamushi and incubated in a medium containing doxycycline (4 µg/mL), azithromycin (0.5 µg/mL), rifampin (4 µg/mL), ciprofloxacin (25 µg/mL), gentamicin (5 µg/mL), cefotaxime (2 µg/mL), or combinations of these agents for 7 days, after which immunofluorescent staining for O. tsutsugamus

ParasitologyImmunology and Microbiology

Research Areas

Cardiology and Cardiovascular MedicineSurgeryPulmonary and Respiratory MedicineEmergency MedicineEndocrinology, Diabetes and MetabolismNephrology

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