Ranji Yoo
Seoul National University · 医学
研究室紹介
Professor Ranji Yoo's research lab specializes in the development and application of advanced nanomaterials for biomedical and environmental sensing, with a strong focus on pulmonary fibrosis and gas detection. The lab investigates the molecular mechanisms of radiation- and idiopathic-induced lung fibrosis, emphasizing endothelial-to-mesenchymal transition and extracellular matrix remodeling. A key research direction involves designing high-performance, selective, and low-detection-limit gas sensors using metal oxide nanoparticles, carbon nitride nanodots, and carbon nanotube-polyaniline composites for real-time monitoring of toxic volatile organic compounds and nitrogen-containing gases. The lab also explores drug delivery systems, such as albumin-based nanocarriers, to enhance the therapeutic efficacy of antifibrotic agents like apigenin.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15PURPOSE: Radiation-induced pulmonary fibrosis (RIPF) is a late side effect of thoracic radiotherapy. The purpose of our study was to gain further insight into the development of RIPF. EXPERIMENTAL DESIGN/RESULTS: Here, we observed that irradiation of mouse lungs induced collagen deposition, particularly around blood vessels, in the early phase of RIPF. Such deposition subsequently became evident throughout the irradiated tissues. Accompanied by the collagen deposition, vascular EndMT (endothelia
Three-dimensional (3D) carbon nitride (C3 N4 )-based materials show excellent performance in a wide range of applications because of their suitable band structures. To realize the great promise of two-dimensional (2D) allotropes of various 3D materials, it is highly important to develop routes for the production of 2D C3 N4 materials, which are one-atom thick, in order to understand their intrinsic properties and identify their possible applications. In this work, water-dispersible, atomically t
In this work, we present the fabrication and characterization of a 2-chloroethyl ethyl sulfide (2-CEES) gas sensor based on ZnO nanoparticles (NPs) synthesized by a hydrothermal method. We confirmed that synthesized ZnO NPs adopt a polycrystalline phase. Partially aggregated ZnO-NPs revealed spherical or ellipsoidal nanocrystalline particles in a size range of 30-50 nm, as observed by field-emission scanning electron microscopy (FE-SEM). The maximum response of the ZnO NPs was 15 at 1 ppm 2-CEES
N-containing gaseous compounds, such as trimethylamine (TMA), triethylamine (TEA), ammonia (NH3), nitrogen monoxide (NO), and nitrogen dioxide (NO2) exude irritating odors and are harmful to the human respiratory system at high concentrations. In this study, we investigated the sensing responses of five sensor materials—Al-doped ZnO (AZO) nanoparticles (NPs), Pt-loaded AZO NPs, a Pt-loaded WO3 (Pt-WO3) thin film, an Au-loaded WO3 (Au-WO3) thin film, and N-doped graphene—to the five aforementione
We reported on the response behaviours of a composite sensor of SWNTs with polyaniline to detect noxious gases at room temperature. The SWNT-polyaniline composite synthesised was found to be high-quality with good uniformity. A combination of photolithography and a lift-off process was utilised to fabricate 100-nm thick Pd electrodes on drop-cast SWNT-polyaniline composite. The composite-based sensor showed high sensitivities to NH3 concentration of 35 ppm and CO concentration of 50 ppm at room