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Sang Guk Han

Sungkyunkwan University · 医学

研究室紹介

Professor Sang Guk Han's research lab specializes in emergency medicine, critical care, and surgical innovation, with a strong focus on infection control during outbreaks such as MERS, optimizing advanced airway management in hazardous environments, and improving outcomes in acute surgical conditions during pregnancy. The lab conducts clinical and simulation-based studies to evaluate resuscitation techniques, diagnostic accuracy using imaging and biomarkers, and the safety and efficacy of minimally invasive surgical approaches. Their work bridges clinical practice with evidence-based innovation to enhance patient safety and healthcare delivery in high-acuity settings.

emergency medicineinfection controlsurgical outcomesresuscitation techniquesacute appendicitis

Research Overview

Papers
56
Total Citations
876
Papers (5y)
17
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
17total
2019
2020
2021
2022
2025
Citations per year (5y)
153total
20192020202120222025

Selected Papers

15
1
Article|294 citations·2006
Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-κB through Akt and p38 inhibition in RAW 264.7 macrophage cells
Ho Gyoung Kim, Bhushan Shrestha, So Yeon Lim, Deok Hyo Yoon, Woochul Chang, Dong-Jik Shin, Sang Kuk Han, Sang‐Min Park, Jung Hee Park, Hae Il Park, Jae-Mo Sung, Yangsoo Jang
SJR Q1European Journal of PharmacologyOA
PharmacologyMedicine
2
Article|131 citations·2007
Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage
Ho Gyoung Kim, Deok Hyo Yoon, Won Ho Lee, Sang Kuk Han, Bhushan Shrestha, Chun Hoi Kim, Mi Hee Lim, Woochul Chang, Soyeon Lim, Sunga Choi, Won O. Song, Jae Mo Sung
SJR Q1Journal of EthnopharmacologyOA
PharmacologyMedicine
3
Article|67 citations·2017
Low-dose CT for the diagnosis of appendicitis in adolescents and young adults (LOCAT): a pragmatic, multicentre, randomised controlled non-inferiority trial
Hyuk Jung Kim, Byeong Geon Jeon, Chong Kun Hong, Kye Won Kwon, Seung Bong Han, Soya Paik, Suk Ki Jang, Young Rock Ha, Young Sik Kim, Min Hee Lee, Boem Ha Yi, Eung Jin Shin
SJR Q1˜The œLancet. Gastroenterology & hepatology
Emergency MedicineMedicine
4
Article|56 citations·2019
Risk of transmission via medical employees and importance of routine infection-prevention policy in a nosocomial outbreak of Middle East respiratory syndrome (MERS): a descriptive analysis from a tertiary care hospital in South Korea
Hyun Kyun Ki, Sang Kuk Han, Jun Seong Son, Sang O Park
SJR Q2BMC Pulmonary MedicineOA

BACKGROUND: In 2015, South Korea experienced an outbreak of Middle East respiratory syndrome (MERS), and our hospital experienced a nosocomial MERS infection. We performed a comprehensive analysis to identify the MERS transmission route and the ability of our routine infection-prevention policy to control this outbreak. METHODS: This is a case-cohort study of retrospectively analysed data from medical charts, closed-circuit television, personal interviews and a national database. We analysed dat

Pulmonary and Respiratory MedicineMedicine
5
Article|38 citations·2011
Tracheal intubation during chest compressions using Pentax-AWS®, GlideScope®, and Macintosh laryngoscope: a randomized crossover trial using a mannequin
Dong Hyuk Shin, Pil Cho Choi, Sang Kuk Han
SJR Q1Canadian Journal of Anesthesia/Journal canadien d anesthésieOA
Anesthesiology and Pain MedicineMedicine
6
Article|38 citations·2009
Utility of the Pentax-AWS® without interruption of chest compression: Comparison of the Macintosh laryngoscope with the Pentax-AWS® in manikin model
Sang Kuk Han, Dong Hyuk Shin, Pil Cho Choi
SJR Q1Resuscitation
Anesthesiology and Pain MedicineMedicine
7
Article|37 citations·2012
Safety and Clinical Efficacy of Laparoscopic Appendectomy for Pregnant Women with Acute Appendicitis
Jeong Min Eom, Jin Hwa Hong, Seung Wook Jeon, Joong Sub Choi, Jung Hun Lee, Hyung Ook Kim, Hungdai Kim, Pil Cho Choi, Sang Kuk Han
SJR Q3Annals of the Academy of Medicine SingaporeOA

INTRODUCTION: The aim of this study was to investigate the clinical efficacy and safety of laparoscopic appendectomy (LA) during pregnancy by comparing the operative and obstetric outcomes of patients who during pregnancy underwent LA performed by an expert gynaecologic laparoscopist (LA group) with those patients who underwent an open appendectomy (OA) by a general surgeon (OA group). MATERIALS AND METHODS: In this retrospective study, we evaluated all patients consecutively who had undergone a

Emergency MedicineMedicine
8
Article|31 citations·2019
Urinary neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury in sepsis patients in the emergency department
Hee Su Park, Jong Won Kim, Jong Won Kim, Kyeong Ryong Lee, Dae Young Hong, Sang O Park, Sin Young Kim, Jin Young Kim, Jin Young Kim, Sang Kuk Han
SJR Q1Clinica Chimica Acta
NephrologyMedicine
9
Article|21 citations·2013
Utility of the Pentax-AWS in performing tracheal intubation while wearing chemical, biological, radiation and nuclear personal protective equipment: a randomised crossover trial using a manikin
Dong Hyuk Shin, Pil Cho Choi, Ji Ung Na, Jun Hwi Cho, Sang Kuk Han
SJR Q1Emergency Medicine Journal

INTRODUCTION: Following a chemical, biological, radiation and nuclear (CBRN) incident, prompt establishment of an advanced airway is required for patients with respiratory failure within the warm zone, while wearing personal protective equipment (PPE). Previous studies reported that intubation attempts were prolonged, and incidence of esophageal intubation was increased with conventional Macintosh laryngoscope (McL), while wearing CBRN-PPE. Pentax-AWS (AWS), a recently introduced portable video

Anesthesiology and Pain MedicineMedicine
10
Article|20 citations·2020
Chronic Gastritis Is Associated with a Decreased High-Density Lipid Level: Histological Features of Gastritis Based on the Updated Sydney System
Dong‐Hoon Kim, Byoung Kwan Son, Kyueng‐Whan Min, Sang Kuk Han, Ji Ung Na, Pil Cho Choi, Hack‐Lyoung Kim, Mi Jung Kwon, Young‐Ha Oh, Woon Yong Jung, Ji‐Yong Moon, Sangmo Hong
SJR Q1Journal of Clinical MedicineOA

(HP), mononuclear cell (lymphocytes and plasma cells), and neutrophil scores were assessed on the basis of the updated Sydney system (USS), which is widely used for histological grading. The aim of this study was to assess the relationships between gastric histological features and lipid profile levels. This study included 15,322 males and 5929 females who underwent a health checkup and gastric biopsy at the Kangbuk Samsung Medical Center (KBSMC). We analyzed whether the HP, mononuclear cell, an

SurgeryMedicine
11
Article|19 citations·2014
A vertical two-thumb technique is superior to the two-thumb encircling technique for infant cardiopulmonary resuscitation
Ji Ung Na, Pil Cho Choi, Hyun Jung Lee, Dong Hyuk Shin, Sang Kuk Han, Jun Hwi Cho
SJR Q1Acta Paediatrica

Aim The two-thumb encircling (TTE) technique often results in suboptimal cardiac compression and does not meet the requirements of current resuscitation guidelines. We compared this technique with the vertical two-thumb (VTT) technique, our novel modification of the TTE technique. Methods This was a prospective randomised crossover simulation study of out-of-hospital infant cardiopulmonary resuscitation (CPR). Participants who had completed a basic life support course performed 10 cycles of card

Emergency MedicineMedicine
12
Article|17 citations·2021
Skin Moisturizing Effects of a Microneedle Patch Containing Hyaluronic Acid and Lonicerae flos
Sang Kuk Han, Seung-Jun Lee, Hun-Yong Ha
SJR Q2ProcessesOA

The utilization of cosmetic raw materials for medicinal purposes in a microneedle patch containing hyaluronic acid (HA) and Lonicerae flos ethanol extract (LEE) has increased based on their eco-friendly characteristics. The moisturizing effects of this microneedle patch were assessed on the forearms of 20 female participants, and our results showed an increase between 29.60% and 88.54% in skin moisture content at the same time points relative to the untreated group. Apart from confirming the saf

Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
13
Article|17 citations·2017
Differential diagnoses of magnetic resonance imaging for suspected acute appendicitis in pregnant patients
Ji Yong Jung, Ji Ung Na, Sang Kuk Han, Pil Cho Choi, Jang Hee Lee, Dong Hyuk Shin
SJR Q2World Journal of Emergency MedicineOA

MRI can reliably differentiate surgical conditions and several blood tests (WBC, proportion of neutrophils in the WBC, NLR, CRP, bilirubin) can help anticipate acute surgical condition among pregnant patients suspected to have acute appendicitis.

Emergency MedicineMedicine
14
Article|17 citations·2013
Influence of face mask design on bag–valve–mask ventilation performance: a randomized simulation study
J. U. NA, Sang Kuk Han, Pil Cho Choi, Jae Hwa Cho, Dong Hyuk Shin
SJR Q2Acta Anaesthesiologica ScandinavicaOA

BACKGROUND: Different face mask designs can influence bag-valve-mask (BVM) ventilation performance during resuscitation. We compared a single-use, air-cushioned face mask (AM) with a reusable silicone face mask (SM) for quality of BVM ventilation on a manikin simulating cardiac arrest. METHODS: Thirty-two physicians were recruited, and a prospective, randomized, crossover observational study was conducted after an American Heart Association-accredited basic life support provider course and stand

Emergency MedicineMedicine
15
Article|10 citations·2020
Proximal hyper-intense vessel sign on initial FLAIR MRI in hyper-acute middle cerebral artery ischemic stroke: a retrospective observational study
Dong Hyuk Shin, Sang Kuk Han, Jang Hee Lee, Pil Cho Choi, Sang O Park, Young Hwan Lee, Ji Ung Na
SJR Q3Acta Radiologica

Background A hyper-intense vessel sign on fluid attenuated inversion recovery magnetic resonance imaging (FHV) represents slow blood flow in the cerebral arteries. Purpose To investigate the relationship between the proximal FHV (pFHV) on initial magnetic resonance imaging (MRI) and the status of the culprit vessel (stenosis, obstruction) in hyper-acute strokes affecting the territory of the middle cerebral artery (MCA). Material and Methods The study participants consisted of 105 patients prese

EpidemiologyMedicine

Research Areas

Emergency MedicineAnesthesiology and Pain MedicineEpidemiologyPharmacologyPulmonary and Respiratory MedicineNephrology

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