So Young Yu
Sungkyunkwan University · 医学
研究室紹介
Professor So Young Yu's research lab focuses on medical imaging and diagnostic applications in pediatric and oncologic conditions, with a strong emphasis on neuroimaging in pediatric stroke syndromes such as MELAS and neonatal ovarian torsion. The lab investigates advanced imaging techniques to understand disease progression, including edema evolution and tissue damage, and evaluates the role of biomarkers like galactomannan in diagnosing invasive aspergillosis in immunocompromised children. Additionally, the lab explores stereotactic radiation therapy for pelvic recurrence in rectal cancer, highlighting outcomes and toxicity profiles. The research integrates radiological findings with clinical and pathological data to improve diagnostic accuracy and patient prognosis.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15The cytotoxic edema gradually evolves following an acute stroke-like episode in patients with MELAS, and this may overlap with hyper-perfusion and vasogenic edema. The edematous swelling may be reversible or it may evolve to encephalomalacia, suggesting irreversible damage.
Although the incidence of DEHSI was high (75%) in preterm infants at near-term-equivalent age MR imaging, DEHSI was not predictive of following adverse outcomes. Cystic encephalomalacia and punctate lesions were more significant predictors of cerebral palsy.
OBJECTIVE: To investigate the clinical applications of stereotactic body radiation therapy (SBRT) using the CyberKnife system for pelvic recurrence from rectal cancer with a focus on survival and toxicity. METHODS: Between 2002 and 2006, 23 patients with recurrent rectal cancer were treated with SBRT at our institution. The median follow-up was 31 months. Sites of recurrence were pre-sacral in seven patients and the pelvic wall in 16. SBRT doses ranged from 30 to 51 Gy (median 39 Gy) and were de
BACKGROUND: Invasive aspergillosis (IA) is a major cause of morbidity and mortality in immunocompromised children. We investigated the usefulness of an Aspergillus galactomannan (GM) antigen assay as a diagnostic tool for IA in pediatric cancer patients and hematopoietic cell transplantation (HCT) recipients. PROCEDURE: The GM antigen assay results were analyzed in 749 blood samples from 99 patients. A GM index (GMI) greater than or equal to 0.5 on at least two separate occasions was considered
PURPOSE: Our aim was to retrospectively review the imaging findings of patients with neonatal ovarian torsion, emphasizing prenatal and postnatal sonographic findings. METHODS: Eleven patients who had had neonatal ovarian torsion diagnosed surgically (n = 9) or clinicoradiologically (n = 2) were enrolled. Prenatal and postnatal sonographic features, including sequential postnatal change, were reviewed. Clinical and pathologic features were also investigated. RESULTS: All patients except one had
Benign hypervascular hepatic nodules in survivors of childhood malignancy occur years after high-dose chemotherapy and hematopoietic stem cell transplantation. Dynamic MRI findings including intense arterial enhancement and absence of washout in the delayed phase are of great value in the differential diagnosis of these hepatic nodules.