Soonho Kwon
Pohang University of Science and Technology · 生化学・遺伝学・分子生物学
研究室紹介
Professor Soonho Kwon's research lab focuses on environmental health and toxicology, particularly the detection and risk assessment of mycotoxins such as ochratoxin A and zearalenone in food systems. The lab also investigates cellular signaling mechanisms, especially calcium dynamics in fibroblasts mediated by growth factors like PDGF, using advanced imaging techniques. Additionally, the lab applies innovative machine learning approaches to atmospheric chemistry, addressing complex challenges in urban air pollution by improving the attribution of ozone-forming precursors. These interdisciplinary efforts span molecular biology, environmental toxicology, and environmental data science.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
6Confocal laser scanning microscopy was used to analyze alterations in nuclear free calcium (Ca2+n) levels induced by platelet-derived growth factor (PDGF) isoforms in BALB/c3T3 fibroblasts loaded with the calcium-sensitive fluorescent indicator Fluo-3. Both AA-PDGF and BB-PDGF caused a transient increase in Ca2+n. Analysis of PDGF-induced Ca2+n alterations as a function of time revealed that BB-PDGF stimulation resulted in the generation of Ca2+n oscillations that diminished over time. The frequ
Confocal laser scanning microscopy was used to analyze alterations in nuclear free calcium (Ca2+n) levels induced by platelet-derived growth factor (PDGF) isoforms in BALB/c3T3 fibroblasts loaded with the calcium-sensitive fluorescent indicator Fluo-3. Both AA-PDGF and BB-PDGF caused a transient increase in Ca2+n. Analysis of PDGF-induced Ca2+n alterations as a function of time revealed that BB-PDGF stimulation resulted in the generation of Ca2+n oscillations that diminished over time. The frequ
Abstract. Ground-level ozone remains a persistent challenge in East Asian urban centers, where concentrations continue rising despite significant reductions in precursor emissions. Designing effective mitigation is complicated by the non-linear relationship between precursor abundance and reactivity. Standard data-driven approaches often suffer from "survivor bias," systematically undervaluing highly reactive precursors that are rapidly depleted. We introduce a process-informed machine learning
This research investigated the concentrations and dietary exposure of ochratoxin A (OTA) and zearalenone (ZEN) in edible vegetable oils among the Korean population. In 2022, 80 edible vegetable oil samples were collected from various retail sources in Korea. OTA was detected in 7.5% of the samples, and ZEN was detected in 62.5%. Dietary intake estimates were based on our findings and food consumption data from the Korean National Health and Nutrition Examination Survey. Dietary exposure was eval
formation are not observed within this time window at the current signal-to-noise ratio, indicating that photofragmentation remains a minor channel up to 100 ps. These results provide element-specific insight into nitroaromatic photochemistry and support a mechanism in which photofragmentation is delayed by transient excited-state trapping.