Sung-young Yu

This is the first nation-wide epidemiologic study conducted in South Korea for assessment of the prevalence of eye diseases by both the Korean Ophthalmologic Society and the Korea Center for Disease Control and Prevention. This study will provide preliminary information for use in further investigation, prevention, and management of eye diseases in Korea.

Single intravitreal injection of 0.5 mg or 1 mg of TA did not produce morphologic retinal changes in pigmented rabbits. However, injections of 4 mg, 8 mg, and 20 mg of TA produced outer retina toxic effects. These findings suggest that long-term retinal toxicity studies should be carried out, using single and repeated injections before this therapy becomes more widely used.

AIM: To evaluate the incidence and prevalence of uveitis and associated risk factors in South Korea. METHODS: For this retrospective national cohort study, approximately 1 000 000 Korean residents were randomly selected from the Korean National Health Insurance Service database. Uveitis was defined according to the Korean Classification of Diseases. The uveitis incidence and prevalence were calculated. Sociodemographic factors and comorbidities associated with uveitis were evaluated via Cox prop

The Korea National Health and Nutrition Examination Survey (KNHANES) is a national program designed to assess the health and nutritional status of the noninstitutionalized population of South Korea. The KNHANES was initiated in 1998 and has been conducted annually since 2007. Starting in the latter half of 2008, ophthalmologic examinations were included in the survey in order to investigate the prevalence and risk factors of common eye diseases such as visual impairment, refractive errors, strab

Purpose: The aim of this study is to report on preliminary data regarding the prevalence of major eye diseases in Korea. Methods: We obtained data from the Korea National Health and Nutrition Examination Survey, a nation-wide cross-sectional survey and examinations of the non-institutionalized civilian population in South Korea (n =14,606), conducted from July 2008 to December 2009. Field survey teams included an ophthalmologist,nurses, and interviewers, traveled with a mobile examination unit a

Various clinical features were associated with DR and ME. Additional epidemiological and biorepository-based studies using this cohort are being conducted to deepen our understanding of diabetic complications in Korea.

The Cirrus HD-OCT had a lower frequency and severity of segmentation error than the Spectralis HRA + OCT. SD-OCT error should be considered when evaluating retinal thickness.

This study provides evidence to suggest that older patients with HM are at a significant risk of the dry and neovascular forms of AMD. NV in eyes with HM and AMD required more injections in the first year compared to NV in HM eyes without AMD.

BACKGROUND/AIMS: To investigate the effects of intravitreal ranibizumab treatment for macular edema (ME) secondary to retinal vein occlusion (RVO) and the relationship between spectral-domain optical coherence tomography (SD-OCT) findings and visual outcome after successful resolution of ME. METHODS: Forty consecutive eyes with ME secondary to branch RVO (BRVO; 29 eyes of 29 patients) or central RVO (CRVO; 11 eyes of 11 patients) were included in a prospective study and treated with 3 initial in

RPE atrophy progresses in eyes with exudative AMD during anti-VEGF treatment. Larger areas of RPE atrophy at month 4 and larger numbers of anti-VEGF injections were associated with an increased risk of progression of RPE atrophy the following treatment. These findings may be useful to clinicians using intravitreal anti-VEGF for the treatment of exudative AMD, both for selecting an appropriate treatment plan and for predicting the progression of RPE atrophy.

PURPOSE: To assess the effectiveness and safety of intravitreal ranibizumab compared with bevacizumab for the treatment of macular edema associated with branch retinal vein occlusion (BRVO). METHODS: This was a retrospective study of 80 eyes with macular edema associated with BRVO. Patients received either 0.5 mg of ranibizumab (n = 24) or 1.25 mg of bevacizumab (n = 56) intravitreally. Both groups received three initial monthly injections followed by as-needed injections. The best-corrected vis

Toxoplasma gondii KI-1, a recent new isolate from Korea, shows similar pathogenicity and infectivity to mice compared to the virulent RH strain. To understand characteristics of host immunity, including immune enhancement or suppression, we investigated proliferative responses and phenotypes of spleen cells. In addition, kinetics of IFN-γ, a Th1 cytokine, was examined in BALB/c mice up to day 6 post-infection (PI). Intraperitoneal injection of mice with 10(3) KI-1 tachyzoites induced significant

목적:당뇨황반부종의 종류에 따른 트리암시놀론 안내주입술(IVTA)의 효과에 대해 알아보고자 하였다. 대상과 방법: 당뇨황반부종환자 31안을 대상으로 IVTA (0.1 cc 40 mg/cc)를 시행하고 치료 1주일, 1개월, 3개월, 6개월 후 OCT (optical coherence tomography, STRATUS OCT model 3000, Carl Zeiss, California)를 이용하여 분류한 당뇨황반부종의 종류에 따른 시력 및 황반부두께 변화를 분석하였다. 결과: 당뇨황반부종환자 31안중 낭포성이 18안 스폰지성이 7안, 장액성박리가 6안이었으며, 황반부두께 변화 및 시력은 술 전에 비해 모두 향상되었으며, 이 중 낭포성 황반부종이 다른 종류에 비해 황반부두께변화 및 시력에서 더 효과가 좋은 것으로 나타났다. 결론: 당뇨황반부종에서 IVTA는 황반부 두께의 감소 및 시력 향상에서 단기간에 효과적인 것으로 관찰되었으며 낭포성 황반부종에서 더 효과적인 것으로 관찰되었다.

BACKGROUND AND OBJECTIVE: To evaluate en face spectral-domain optical coherence tomography (SD-OCT) findings of the outer retinal hard exudates in diabetic macular edema (DME). PATIENTS AND METHODS: Exploratory analyses of prospective and consecutive case series. Fifty-five eyes treated with intravitreal ranibizumab (IVR) (Lucentis; Genentech, South San Francisco, CA) for 12 months were classified according to OCT features of DME: diffuse retinal thickening (DRT), cystoid macular edema (CME), an

목적: 정상인과 당뇨황반부종(DME)환자에서 시간영역 빛간섭단층촬영기(TD-OCT)와 스펙트럼영역 빛간섭단층촬영기(SD-OCT) 2종을 이용 하여 황반두께를 측정하고 각 기종별 두께 측정치의 차이와 반복성을 알아보았다. 대상과 방법: 정상인 54안과 DME환자 26안을 대상으로 Stratus OCT, Cirrus HD-OCT, Spectralis HRA+OCT를 이용하여 황반두께를 2회 순차적으로 측정한 후 9개의 영역으로 나누어 기기 3종의 측정치를 비교하고 반복성 값을 구하였다. 결과: 반복성은 TD-OCT보다 SD-OCT에서 더 좋았다. 황반두께 측정치는 정상인과 DME환자에서 모두 Spectralis HRA+OCT, Cirrus HD-OCT, Stratus OCT 순으로 높게 측정되었으며, 정상인에서는 기기별로 어떤 조합으로 비교하더라도 9개 영역 모두에서 의미있는 차이가 있었다. 결론: SD-OCT와 TD-OCT 모두 반복성이 뛰어났으나 SD-OCT의 반복성이 더 뛰어난 것