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Sungwook Seo

Sungkyunkwan University · 医学

研究室紹介

Professor Sungwook Seo's research lab specializes in translational oncology and musculoskeletal oncology, focusing on improving diagnostic accuracy and treatment strategies for rare and aggressive sarcomas such as chondrosarcoma and myxoid liposarcoma. The lab integrates advanced imaging techniques, including whole-body MRI, with molecular biology approaches—such as siRNA-mediated gene silencing—to enhance radiosensitivity and understand metastatic patterns. A key emphasis is on developing personalized prognostic models using genomic biomarkers, particularly in epithelial ovarian cancer (EOC), and advancing artificial intelligence literacy in medical education to support future clinical decision-making. The lab also investigates musculoskeletal complications in genetic disorders like Prader-Willi syndrome, advocating for early and systematic orthopedic screening.

sarcomawhole-body MRIprognostic biomarkersartificial intelligence in medicinemusculoskeletal oncology

Research Overview

Papers
67
Total Citations
1,301
Papers (5y)
13
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2020
2022
2023
2024
2025
Citations per year (5y)
64total
20202022202320242025

Selected Papers

15
1
Article|110 citations·2012
Surgical outcome of Schwannomas arising from major peripheral nerves in the lower limb
Sang‐Min Kim, Sung Wook Seo, Juneyoung Lee, Ki-Sun Sung
SJR Q1International OrthopaedicsOA
NeurologyMedicine
2
Review|102 citations·2012
The diagnostic utility of the GNAS mutation in patients with fibrous dysplasia: meta-analysis of 168 sporadic cases
Seung Eun Lee, Eun Hee Lee, Heejung Park, Ji‐Youn Sung, Hyoun Wook Lee, So Young Kang, Sung Wook Seo, Byung Heon Kim, Hyojin Lee, An Na Seo, Geunghwan Ahn, Yoon‐La Choi
SJR Q1Human Pathology
RheumatologyMedicine
3
Article|85 citations·2009
The diagnostic value of needle biopsy for musculoskeletal lesions
Ki-Sun Sung, Sung Wook Seo, Min-Soo Shon
SJR Q1International Orthopaedics
Pulmonary and Respiratory MedicineMedicine
4
Article|79 citations·2019
Prediction of survival outcomes in patients with epithelial ovarian cancer using machine learning methods
E Sun Paik, Jeong‐Won Lee, Jeong‐Yeol Park, Ju-Hyun Kim, Mijung Kim, Tae‐Joong Kim, Chel Hun Choi, Byoung‐Gie Kim, Duk‐Soo Bae, Sung Wook Seo
SJR Q1Journal of Gynecologic OncologyOA

Our novel GB-guided classification accurately identified the prognostic subgroups of patients with EOC and showed higher accuracy than the conventional method. This approach would be useful for accurate estimation of individual outcomes of EOC patients.

Reproductive MedicineMedicine
5
Article|69 citations·2019
Soft tissue sarcoma: DWI and DCE-MRI parameters correlate with Ki-67 labeling index
Ji Hyun Lee, Young Cheol Yoon, Sung Wook Seo, Yoon‐La Choi, Hyun Su Kim
SJR Q1European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
6
Article|60 citations·2010
Clinical and Radiographic Results of Lateral Condylar Fracture of Distal Humerus in Children
Kyoung Hwan Koh, Sung Wook Seo, Kyung Mu Kim, Jong Sup Shim
SJR Q2Journal of Pediatric Orthopaedics

Case series, Level IV.

RehabilitationMedicine
7
Article|58 citations·2007
Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells
Dae Won Kim, Sung Wook Seo, Samuel K. Cho, Seong Sil Chang, Ho‐Won Lee, Se Eun Lee, Joel A. Block, Tom K. Hei, Francis Y. Lee
SJR Q1Journal of Orthopaedic Research®

The main treatment for chondrosarcoma is surgical resection with a wide margin. However, there are certain chondrosarcomas, such as those found in the pelvis and the spine, which cannot be resected adequately with surgery alone. Unfortunately, most chondrosarcomas are resistant to radiation and chemotherapy. Radiation and chemotherapy are thought to kill chondrosarcoma cells by inducing apoptosis, or programmed cell death. In this article, we hypothesize that antiapoptotic gene silencing enhance

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|53 citations·2014
Prognostic value of 18F-FDG PET/CT in patients with soft tissue sarcoma: comparisons between metabolic parameters
Sun-pyo Hong, Seung Eun Lee, Yoon‐La Choi, Sung Wook Seo, Ki-Sun Sung, Hong Hoe Koo, Joon Young Choi
SJR Q2Skeletal Radiology
Pulmonary and Respiratory MedicineMedicine
9
Article|48 citations·2023
Defining Medical AI Competencies for Medical School Graduates: Outcomes of a Delphi Survey and Medical Student/Educator Questionnaire of South Korean Medical Schools
Young‐Mee Lee, Suyoun Kim, Young‐Hee Lee, Hun‐Sung Kim, Sung Wook Seo, Hwiyoung Kim, Kwang Joon Kim
SJR Q1Academic MedicineOA

PURPOSE: Given the increasing significance and potential impact of artificial intelligence (AI) technology on health care delivery, there is an increasing demand to integrate AI into medical school curricula. This study aimed to define medical AI competencies and identify the essential competencies for medical graduates in South Korea. METHOD: An initial Delphi survey conducted in 2022 involving 4 groups of medical AI experts (n = 28) yielded 42 competency items. Subsequently, an online question

Health InformaticsMedicine
10
Article|45 citations·2010
The Musculoskeletal Manifestations of Prader-Willi Syndrome
Jong Sup Shim, Sang Hak Lee, Sung Wook Seo, Kyung Hyo Koo, Dong‐Kyu Jin
SJR Q2Journal of Pediatric Orthopaedics

This study shows a high prevalence of spinal deformity, limb malalignment, and foot abnormality in PWS. The prevalences of musculoskeletal abnormalities were not found to be affected by age, genotype, or obesity. However, several musculoskeletal abnormalities were found to be correlated with each other, namely, scoliosis and limb malalignment, kyphotic deformity, and foot abnormality or severe limb malalignment. The authors recommend that pediatric orthopaedic surgeons conduct systemic clinical

GeneticsBiochemistry, Genetics and Molecular Biology
11
Article|38 citations·2018
Prediction of Overall Survival and Novel Classification of Patients with Gastric Cancer Using the Survival Recurrent Network
Sung Eun Oh, Sung Wook Seo, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Sung Kim
SJR Q1Annals of Surgical Oncology
Pulmonary and Respiratory MedicineMedicine
12
Article|34 citations·2011
Feasibility of Whole-body MRI for Detecting Metastatic Myxoid Liposarcoma: A Case Series
Sung Wook Seo, Jong Won Kwon, Sung Won Jang, Seung Pil Jang, Youn-Soo Park
SJR Q2Orthopedics

No feasible method currently exists to evaluate systemic metastasis in patients with myxoid liposarcoma. The purpose of this study was to determine the feasibility of performing whole-body magnetic resonance imaging (MRI) to detect metastatic myxoid liposarcoma. From June 2008 to May 2010, all patients who were newly diagnosed with myxoid liposarcomas at our institution underwent whole-body MRI along with other conventional imaging methods. We divided the whole body into 38 sections (7 soft tiss

Pulmonary and Respiratory MedicineMedicine
13
Article|25 citations·2013
Surgical outcome of desmoid tumors: Adjuvant radiotherapy delayed the recurrence, but did not affect long‐term outcomes
Seung Han Shin, Kyung Rae Ko, Samuel K. Cho, Yoon‐La Choi, Sung Wook Seo
SJR Q1Journal of Surgical Oncology

BACKGROUND: We retrospectively reviewed the outcomes of desmoid tumor (DT) patients treated by surgical excision. METHODS: Among 155 consecutive patients, 119 patients satisfied our inclusion criteria. The mean follow-up duration was 82 months. Age, gender, location, size, depth, resection margin, adjuvant radiotherapy, and excision history were analyzed for the outcomes. RESULTS: The recurrence-free survival (RFS) rates were 75% at 5 years and 72% at 10 years. Twenty-seven (93.1%) out of 29 rec

RheumatologyMedicine
14
Article|24 citations·2018
Deep Learning–Based Survival Analysis Identified Associations Between Molecular Subtype and Optimal Adjuvant Treatment of Patients With Gastric Cancer
Jeeyun Lee, Ji Yeong An, Min Gew Choi, Se Hoon Park, Seung Tae Kim, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Sung Hoon Kim, Hyuk Lee, Byung-Hoon Min, Jae J. Kim
SJR Q1JCO Clinical Cancer InformaticsOA

PURPOSE: Gastric cancer (GC) is the third-leading cause of cancer-related deaths. Several pivotal clinical trials of adjuvant treatments were performed during the previous decade; however, the optimal regimen for adjuvant treatment of GC remains controversial. PATIENTS AND METHODS: We developed a novel deep learning-based survival model (survival recurrent network [SRN]) in patients with GC by including all available clinical and pathologic data and treatment regimens. This model uses time-seque

Pulmonary and Respiratory MedicineMedicine
15
Article|14 citations·2018
A Longitudinal Study of Functional Outcomes in Patients with Limb Salvage Surgery for Soft Tissue Sarcoma
Eunsun Oh, Sung Wook Seo, Kwang Joon Han
SJR Q2SarcomaOA

BACKGROUND: Many studies have reported on the surgical outcomes of soft tissue sarcoma. However, there was no longitudinal cohort study. Because time is the most valuable factor for functional recovery, adjusting time value was the key for finding the causal relationship between other risk factors and postoperative function. Therefore, existing cross-sectional studies can neither fully explain the causal relationship between the risk factors and the functional score nor predict functional recove

Pulmonary and Respiratory MedicineMedicine

Research Areas

Pulmonary and Respiratory MedicineMolecular BiologySurgeryRheumatologyRehabilitationRadiology, Nuclear Medicine and Imaging

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