Tack Kyun Kwon
Seoul National University · 医学
研究室紹介
Professor Tack Kyun Kwon's research lab specializes in laryngeal phonosurgery and injectable laryngoplasty, focusing on the clinical application and long-term safety of biomaterials such as calcium hydroxylapatite (CaHA) and hyaluronic acid (HA) for vocal fold augmentation. The lab investigates the radiological behavior of these injectables using CT and PET imaging, evaluates their efficacy in conditions like presbylaryngis and unilateral vocal fold paralysis, and explores the immunogenetic basis of laryngeal diseases such as recurrent respiratory papillomatosis. A key emphasis is placed on office-based, minimally invasive procedures performed under local anesthesia, with long-term outcomes and complication profiles analyzed over a decade of clinical practice.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15In recent years, the application of injection laryngoplasty to unilateral vocal fold paralysis (UVP) has regained popularity. The technique of injection laryngoplasty has several appealing qualities including relative technical ease, low cost, and wide availability in many clinical settings. A growing number of injectable substances have been developed and tested in the clinical setting of glottic insufficiency. When used to manage unilateral vocal fold paralysis, however, injection laryngoplast
OBJECTIVES/HYPOTHESIS: Presbylaryngis is a normal part of the aging process, but many people visit hospitals with communication difficulties. The authors evaluated the efficacy of calcium hydroxylapatite (CaHA) injection laryngoplasty in patients with presbylaryngis. STUDY DESIGN: Retrospective review. METHODS: Thirty-three patients with diagnosed presbylaryngis were administered a CaHA injection, and 17 of these patients without other vocal pathologies were included in the analysis. All 17 were
OBJECTIVE: To evaluate the safety of office-based calcium hydroxylapatite (CaHA) injection laryngoplasty via the cricothyroid approach through an analysis of all procedures performed over a period of 10 years at a single institution. METHODS: In total, 962 office-based CaHA injection laryngoplasty via the cricothyroid approach procedures were performed by a single physician at our institution between 2007 and 2016. From these, 955 procedures performed in 617 patients were included in our analysi
A linear association between injury level and maximum recovery time was observed. The findings suggest that the decision to proceed with permanent phonosurgical treatment should be based on the level of injury associated with UVFP.
OBJECTIVES/HYPOTHESIS: This study aimed to demonstrate the radiological properties of hyaluronic acid (HA) and calcium hydroxylapatite (CAHA) on serial computed tomography (CT) and positron emission tomography (PET) scan. STUDY DESIGN: Retrospective Case Series. METHOD: Retrospective chart and imaging analysis of patients who underwent HA or CAHA injection laryngoplasty. RESULT: Total of 243 patients who underwent more than one CT of PET after last injection laryngoplasty were included. Sixty-ei
BACKGROUND: FoxP3 is the most dependable marker for regulatory T cells which play a major role in immune tolerance. Foxp3 gene polymorphisms were associated with various autoimmune diseases and clearance of viral infections. We studied the association of Foxp3 polymorphisms in severe RRP patients. METHODS: A total of 30 Korean severe RRP patients and 195 healthy controls were enrolled. Foxp3 polymorphisms (rs5902434 del/ATT, rs3761548 C/A, rs3761549 C/T, and rs2232365 G/A) were determined by PCR
Objectives: The aim of this study was to analyze the risk of malignancy in salivary gland tumors on the basis of the Milan System for Reporting Salivary Gland Cytopathology. Methods: A retrospective review was performed of the charts of patients with salivary gland tumors in whom the final diagnosis was confirmed by surgical excision. Preoperative fine needle aspiration results were categorized according to the Milan System for Reporting Salivary Gland Cytopathology: non-diagnostic (category I),
OBJECTIVES: We sought to develop a less-invasive alternative to conventional arytenoid adduction using a cricoid implant. METHODS: We performed a preliminary study with excised human and canine larynges. A nail-shaped stainless steel rod and an insertion device were designed for an in vivo animal trial. After unilateral recurrent laryngeal denervation surgery in 5 adult mongrel dogs, the implants were inserted endoscopically through a small mucosal incision over the cricoarytenoid joint. Acousti
In all, 24 patients were treated with the endoscopic technique. Among the six open laryngotracheal reconstructions, cricoid splitting and rib cartilage graft were performed in four patients and laryngotracheal resection and end-to-end anastomosis were performed in two patients. Stenosis to normal ratio tended to increase after endoscopic intervention, but it did not show statistical significance (p = 0.082). Open surgery did not cause significant narrowing (p = 0.443).