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Tae Hee Hong

Yonsei University · 医学

研究室紹介

Professor Tae Hee Hong's research lab specializes in advanced critical care interventions and thoracic surgery, with a strong focus on extracorporeal membrane oxygenation (ECMO) and its applications in cardiogenic shock and post-cardiac arrest support. The lab investigates innovative percutaneous venting techniques—such as transaortic catheter venting (TACV)—to improve left ventricular decompression during venoarterial ECMO, aiming to enhance patient recovery and weaning outcomes. Additionally, the lab contributes to surgical oncology, particularly in complex lung resections like extended sleeve lobectomy, and explores biomarkers such as tumor mutational burden (TMB) to optimize immunotherapy response prediction in lung cancer. The integration of interventional critical care, minimally invasive surgery, and precision oncology defines the lab’s multidisciplinary approach.

ECMOleft ventricular decompressionthoracic surgerytumor mutational burdencritical care

Research Overview

Papers
59
Total Citations
503
Papers (5y)
34
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
34total
2022
2023
2024
2025
2026
Citations per year (5y)
142total
20222023202420252026

Selected Papers

15
1
editorial|39 citations·2020
Single-cell genomics technology: perspectives
Tae Hee Hong, Woong‐Yang Park
SJR Q1Experimental & Molecular MedicineOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
Article|37 citations·2015
Successful Left-Heart Decompression during Extracorporeal Membrane Oxygenation in an Adult Patient by Percutaneous Transaortic Catheter Venting
Tae Hee Hong, Joung Hun Byun, Byung Ha Yoo, Sang Won Hwang, Han Yong Kim, Jae Hong Park
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Venoarterial extracorporeal membrane oxygenation (VA ECMO) is widely used in patients with cardiogenic shock. Insufficient decompression of the left ventricle (LV) is considered a major factor preventing adequate LV recovery. A 40-year-old male was diagnosed with acute myocardial infarction, and revascularization was performed using percutaneous stenting. However, cardiogenic shock occurred, and VA ECMO was initiated. Severe LV failure developed, and percutaneous transaortic catheter venting (TA

Biomedical EngineeringEngineering
3
Article|35 citations·2018
Extended sleeve lobectomy for centrally located non-small-cell lung cancer: a 20-year single-centre experience†
Tae Hee Hong, Jong Ho Cho, Sumin Shin, Hong Kwan Kim, Yong Soo Choi, Jae Il Zo, Young Mog Shim, Jhingook Kim
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

OBJECTIVES: Extended sleeve lobectomy (ESL), an atypical bronchoplasty with resection of more than 1 lobe, might be technically demanding but has certain theoretical advantages, including the avoidance of pneumonectomy. However, clinical outcomes after ESL are not well known. METHODS: Between March 1995 and December 2015, 540 patients with centrally located non-small-cell lung cancer underwent sleeve resection. Among them, 63 patients underwent an ESL procedure. We retrospectively analysed those

Pulmonary and Respiratory MedicineMedicine
4
Article|34 citations·2015
Initial Experience of Transaortic Catheter Venting in Patients with Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock
Tae Hee Hong, Joung Hun Byun, Hee Moon Lee, Yong Hwan Kim, Guhyun Kang, Ju Hyeon Oh, Sang Won Hwang, Han Yong Kim, Jae Hong Park
SJR Q1ASAIO Journal

Extracorporeal membrane oxygenation (ECMO) has become one of the often applied mechanical support for acute cardiogenic shock. During venoarterial (VA) ECMO support, left heart decompression should be considered when left ventricular (LV) distension develops with pulmonary edema and LV dysfunction. The aim of this study was to report the results of transaortic catheter venting (TACV), as an alternative venting method, performed during VA-ECMO in patients with acute cardiogenic shock. We retrospe

Biomedical EngineeringEngineering
5
Article|27 citations·2024
Clinical Utility of Tumor-Naïve Presurgical Circulating Tumor DNA Detection in Early-Stage NSCLC
Tae Hee Hong, Soohyun Hwang, Abhijit Dasgupta, Chris Abbosh, Tiffany Hung, Jörg Bredno, Jill Walker, Xiaojin Shi, Tsveta Milenkova, Leora Horn, Joon Young Choi, Ho Yun Lee
SJR Q1Journal of Thoracic Oncology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|17 citations·2020
Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity
Tae Hee Hong, Hongui Cha, Joonho Shim, Boram Lee, Jongsuk Chung, Chung Lee, Nayoung K. D. Kim, Yoon‐La Choi, Soohyun Hwang, Yoomi Lee, Sehhoon Park, Hyun Ae Jung
SJR Q1Journal for ImmunoTherapy of CancerOA

BACKGROUND: Tumor mutational burden (TMB) measurement is limited by low tumor purity of samples, which can influence prediction of the immunotherapy response, particularly when using whole-exome sequencing-based TMB (wTMB). This issue could be overcome by targeted panel sequencing-based TMB (pTMB) with higher depth of coverage, which remains unexplored. METHODS: We comprehensively reanalyzed four public datasets of immune checkpoint inhibitor (ICI)-treated cohorts (adopting pTMB or wTMB) to test

OncologyMedicine
7
Article|13 citations·2021
Role of Recurrent Laryngeal Nerve Lymph Node Dissection in Surgery of Early-Stage Esophageal Squamous Cell Carcinoma
Tae Hee Hong, Hong Kwan Kim, Genehee Lee, Sumin Shin, Jong Ho Cho, Yong Soo Choi, Jae Ill Zo, Young Mog Shim
SJR Q1Annals of Surgical Oncology
SurgeryMedicine
8
Article|9 citations·2020
Clinical outcomes of microscopic residual disease after bronchial sleeve resection for non–small cell lung cancer
Tae Hee Hong, Jhingook Kim, Sumin Shin, Hong Kwan Kim, Yong Soo Choi, Jae Il Zo, Young Mog Shim, Jong Ho Cho
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
Pulmonary and Respiratory MedicineMedicine
9
Article|7 citations·2025
Association of pre-surgical circulating tumor DNA detection, use of sublobar resection with risk of recurrence in stage I non-small cell lung cancer
Tae Hee Hong, Soohyun Hwang, Chris Abbosh, Abhijit Dasgupta, Yeong Jeong Jeon, Jung Hee Lee, Sung Yong Park, Jong Ho Cho, Yong Soo Choi, Young Mog Shim, Tiffany Hung, Joerg Bredno
SJR Q1European Journal of Cancer
Cancer ResearchBiochemistry, Genetics and Molecular Biology
10
Article|6 citations·2017
Delayed Iatrogenic Diaphragmatic Hernia after Left Lower Lobectomy
Tae Hee Hong, Yong Soo Choi
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

A 66-year-old patient undergoing regular follow-up at Samsung Medical Center after left lower lobectomy visited the emergency department around 9 months postoperatively because of nausea and vomiting after routine esophagogastroduodenoscopy at a local clinic. Abdominal computed tomography showed the stomach herniating into the left thoracic cavity. We explored the pleural cavity via video-assisted thoracic surgery (VATS). Adhesiolysis around the herniated stomach and laparotomic reduction under

SurgeryMedicine
11
Article|6 citations·2017
Inter-Facility Transport on Extracorporeal Life Support: Clinical Outcomes and Comparative Analysis with In-house Patients
Tae Hee Hong, Heemoon Lee, Jae Jun Jung, Yang Hyun Cho, Kiick Sung, Ji‐Hyuk Yang, Young-Tak Lee, Su Hyun Cho, R. N
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

BACKGROUND: Extracorporeal life support (ECLS) is widely used in refractory heart or lung failure, and the demand for inter-facility transportation on ECLS is expanding. However, little is known about post-transportation outcomes, the clinical safety of such transportation, or the characteristics of the transported patients. METHODS: This was a retrospective review of a 3-year, single-institution experience with inter-facility ECLS transport, as well as a comparative analysis of clinical outcome

Biomedical EngineeringEngineering
12
Article|5 citations·2023
Clinical Significance of the Proposed Pathologic Criteria for Invasion by the International Association for the Study of Lung Cancer in Resected Nonmucinous Lung Adenocarcinoma
Tae Hee Hong, Soohyun Hwang, Juhee Cho, Yoon‐La Choi, Joungho Han, Genehee Lee, Yeong Jeong Jeon, Jung Hee Lee, Sung Yong Park, Jong Ho Cho, Yong Soo Choi, Young Tae Kim
SJR Q1Journal of Thoracic OncologyOA
Pulmonary and Respiratory MedicineMedicine
13
erratum|5 citations·2017
Erratum: Inter-Facility Transport on Extracorporeal Life Support: Clinical Outcomes and Comparative Analysis with In-house Patients
Tae Hee Hong, Heemoon Lee, Jae Jun Jung, Yang Hyun Cho, Kiick Sung, Ji‐Hyuk Yang, Young-Tak Lee, Su Hyun Cho
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Tae Hee Hong, Heemoon Lee, Jae Jun Jung, Yang Hyun Cho, Kiick Sung, Ji-Hyuk Yang, Young-Tak Lee, and Su Hyun Cho. Korean J Thorac Cardiovasc Surg 2017;50:479. https://doi.org/10.5090/kjtcs.2017.50.6.479

Biomedical EngineeringEngineering
14
Article|4 citations·2023
Programmed Death-Ligand 1 Copy Number Alteration as an Adjunct Biomarker of Response to Immunotherapy in Advanced NSCLC
Tae Hee Hong, Yeong Hak Bang, Cheol Yong Joe, Soohyun Hwang, Boram Lee, Naeun Lee, Sehhoon Park, Hyun Ae Jung, Jong‐Mu Sun, Jin Seok Ahn, Myung‐Ju Ahn, Yoon-La Choi
SJR Q1Journal of Thoracic OncologyOA

This is the first study to directly compare CN alterations with IHC results and survival outcomes after anti-PD-(L)1 therapy. Tumor PD-L1 CN loss can serve as an adjunct biomarker to predict the lack of response. Prospective studies are required to further validate this biomarker.

OncologyMedicine
15
Article|3 citations·2019
Graft Strategy for Coronary Artery Bypass Grafting in Patients with Severe Left Ventricular Dysfunction
Tae Hee Hong, You Jin Ha, Dong Seop Jeong, Wook Sung Kim, Young Tak Lee
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

BACKGROUND: Optimal graft selection for coronary artery bypass grafting (CABG) in patients with severe left ventricular (LV) dysfunction remains debatable. We report an analysis of our experiences of isolated CABG in patients with severe LV dysfunction and the impact of graft strategy on long-term outcomes. METHODS: We analyzed 209 patients with severe LV dysfunction (ejection fraction [EF] <30%) who underwent primary isolated CABG. Of these, 169 were revascularized with a bilateral internal tho

SurgeryMedicine

Research Areas

Pulmonary and Respiratory MedicineOncologySurgeryBiomedical EngineeringCancer ResearchMolecular Biology

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