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Utkarsh Mangal

Yonsei University · 歯学

研究室紹介

Professor Utkarsh Mangal's research lab specializes in the development of advanced biomaterials for dental and biomedical applications, with a focus on enhancing the mechanical, surface, and antimicrobial properties of 3D-printed polymers. The lab investigates nanomaterials such as nanodiamonds and zwitterionic polymers to improve biocompatibility, reduce biofilm formation, and increase the durability of dental implants and prosthetics. Key research directions include surface engineering of poly(methyl methacrylate) (PMMA) and acrylate-based resins for intraoral applications, as well as optimizing post-processing techniques for 3D-printed dental devices. The lab integrates materials science, biofilm dynamics, and clinical dentistry to design patient-specific, infection-resistant medical devices.

3D printingnanomaterialszwitterionic polymersbiofilm resistancedental biomaterials

Research Overview

Papers
72
Total Citations
681
Papers (5y)
48
Primary Field
歯学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
48total
2022
2023
2024
2025
2026
Citations per year (5y)
245total
20222023202420252026

Selected Papers

15
1
Article|67 citations·2019
Novel Poly(Methyl Methacrylate) Containing Nanodiamond to Improve the Mechanical Properties and Fungal Resistance
Utkarsh Mangal, Ji‐Yeong Kim, Ji‐Young Seo, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q2MaterialsOA

Herein we evaluate the effect of nanodiamond (ND) incorporation on the mechanical properties of poly(methyl methacrylate) (PMMA) nanocomposite. Three quantities of ND (0.1, 0.3, and 0.5 wt.%) were tested against the control and zirconium oxide nanoparticles (ZrO). Flexural strength and elastic modulus were measured using a three-point bending test, surface hardness was evaluated using the Vickers hardness test, and surface roughness was evaluated using atomic force microscopy (AFM), while fungal

OrthodonticsDentistry
2
Article|66 citations·2021
Durable Oral Biofilm Resistance of 3D-Printed Dental Base Polymers Containing Zwitterionic Materials
Jae‐Sung Kwon, Ji‐Yeong Kim, Utkarsh Mangal, Ji‐Young Seo, Myung-Jin Lee, Jie Jin, Jae‐Hun Yu, Sung‐Hwan Choi
SJR Q1International Journal of Molecular SciencesOA

Poly(methyl methacralyate) (PMMA) has long been used in dentistry as a base polymer for dentures, and it is recently being used for the 3D printing of dental materials. Despite its many advantages, its susceptibility to microbial colonization remains to be overcome. In this study, the interface between 3D-printed PMMA specimens and oral salivary biofilm was studied following the addition of zwitterionic materials, 2-methacryloyloxyethyl phosphorylcholine (MPC) or sulfobetaine methacrylate (SB).

OrthodonticsDentistry
3
Article|53 citations·2020
Incorporating Aminated Nanodiamonds to Improve the Mechanical Properties of 3D-Printed Resin-Based Biomedical Appliances
Utkarsh Mangal, Ji‐Young Seo, Jae‐Hun Yu, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q1NanomaterialsOA

The creation of clinically patient-specific 3D-printed biomedical appliances that can withstand the physical stresses of the complex biological environment is an important objective. To that end, this study aimed to evaluate the efficacy of aminated nanodiamonds (A-NDs) as nanofillers in biological-grade acrylate-based 3D-printed materials. Solution-based mixing was used to incorporate 0.1 wt% purified nanodiamond (NDs) and A-NDs into UV-polymerized poly(methyl methacrylate) (PMMA). The ND and A

OrthodonticsDentistry
4
Article|51 citations·2021
A Comparison of Accuracy of Different Dental Restorative Materials between Intraoral Scanning and Conventional Impression-Taking: An In Vitro Study
Jung-Hwa Lim, Utkarsh Mangal, Na-Eun Nam, Sung‐Hwan Choi, June‐Sung Shim, Jong‐Eun Kim
SJR Q2MaterialsOA

The properties of underlying substrates influence the quality of an intraoral scan, but few studies have compared the outcomes using common restorative materials. In this study, we aimed to compare the accuracy of digital and conventional impressions recorded for four different dental materials as the substrates. Experimental crowns were produced with a metallic surface (gold or cobalt-chromium alloy (Co-Cr)) or without a metallic surface (zirconia or PMMA (polymethyl methacrylate)). A conventio

OrthodonticsDentistry
5
Article|38 citations·2020
Changes in tribological and antibacterial properties of poly(methyl methacrylate)-based 3D-printed intra-oral appliances by incorporating nanodiamonds
Utkarsh Mangal, You Jin Min, Ji‐Young Seo, Dae‐Eun Kim, Jung‐Yul Cha, Kee‐Joon Lee, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q2Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materialsOA
OrthodonticsDentistry
6
Review|33 citations·2020
Bio-Interactive Zwitterionic Dental Biomaterials for Improving Biofilm Resistance: Characteristics and Applications
Utkarsh Mangal, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q1International Journal of Molecular SciencesOA

Biofilms are formed on surfaces inside the oral cavity covered by the acquired pellicle and develop into a complex, dynamic, microbial environment. Oral biofilm is a causative factor of dental and periodontal diseases. Accordingly, novel materials that can resist biofilm formation have attracted significant attention. Zwitterionic polymers (ZPs) have unique features that resist protein adhesion and prevent biofilm formation while maintaining biocompatibility. Recent literature has reflected a ra

PeriodonticsDentistry
7
Article|26 citations·2024
Evaluation of the effects of temperature and centrifugation time on elimination of uncured resin from 3D-printed dental aligners
Ji-Eun Kim, Utkarsh Mangal, Jae-Hun Yu, Gi-Tae Kim, Hoon Kim, Ji-Young Seo, Jung-Yul Cha, Kee‐Joon Lee, Jae-Sung Kwon, Sung-Hwan Choi
SJR Q1Scientific ReportsOA

The study investigated the effects of temperature and centrifugation time on the efficacy of removing uncured resin from 3D-printed clear aligners. Using a photo-polymerizable polyurethane resin (Tera Harz TC-85, Graphy Inc., Seoul, Korea), aligners were printed and subjected to cleaning processes using isopropyl alcohol (IPA) or centrifugation (g-force 27.95g) at room temperature (RT, 23 °C) and high temperature (HT, 55 °C) for 2, 4, and 6 min. The control group received no treatment (NT). Clea

OrthodonticsDentistry
8
Article|23 citations·2023
Occlusive membranes for guided regeneration of inflamed tissue defects
Woojin Choi, Utkarsh Mangal, Jin‐Young Park, Ji‐Yeong Kim, Taesuk Jun, Ju Won Jung, Moonhyun Choi, Sung-Won Jung, Milae Lee, Ji-Yeong Na, Du Yeol Ryu, Jin‐Man Kim
SJR Q1Nature CommunicationsOA

Guided bone regeneration aided by the application of occlusive membranes is a promising therapy for diverse inflammatory periodontal diseases. Symbiosis, homeostasis between the host microbiome and cells, occurs in the oral environment under normal, but not pathologic, conditions. Here, we develop a symbiotically integrating occlusive membrane by mimicking the tooth enamel growth or multiple nucleation biomineralization processes. We perform human saliva and in vivo canine experiments to confirm

UrologyMedicine
9
Review|15 citations·2017
Influence of Platelet Rich Plasma on Orthodontic Tooth Movement: A Review
Utkarsh Mangal
SJR Q4Biomedical & Pharmacology JournalOA

Introduction Since the inception of the practice of orthodontics, one of the domain in the research has been the tooth movement and associated biological reaction. Research has been done to study various approaches to achieve tooth movement with most physiological manner but with maximum pace. Th

Developmental and Educational PsychologyPsychology
10
Article|13 citations·2022
Changes in mechanical and bacterial properties of denture base resin following nanoceria incorporation with and without SBA-15 carriers
Utkarsh Mangal, Ji‐Young Seo, Jeong‐Hyun Ryu, Jie Jin, Chengzan Wu, Jung‐Yul Cha, Kee‐Joon Lee, Hyung‐Seog Yu, Kwang‐Mahn Kim, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q2Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materialsOA
Materials ChemistryMaterials Science
11
Article|13 citations·2020
Effects of Changes in the Frankfort Horizontal Plane Definition on the Three-Dimensional Cephalometric Evaluation of Symmetry
Utkarsh Mangal, Jae Joon Hwang, Heon Jo, Sung Min Lee, Yun‐Hoa Jung, Bong‐Hae Cho, Jung‐Yul Cha, Sung‐Hwan Choi
SJR Q2Applied SciencesOA

The plane formed by the intersection of bilateral porions (PoR and PoL) and left orbitale (OrL) is conventionally defined as the Frankfort horizontal (FH) plane. We aim to test the influence of the FH plane definition on a 3D cephalometric assessment. We selected 38 adult patients (20 males, 18 females; average age: 22.87 ± 5.17 years) without any gross asymmetry from retrospective records and traced and analyzed their cone-beam computed tomographic images. The findings were categorized into the

Oral SurgeryDentistry
12
Article|9 citations·2023
Multistability and hysteresis in states of oral microbiota: Is it impacting the dental clinical cohort studies?
Utkarsh Mangal, Kowoon Noh, Seeyoon Lee, Jae‐Kook Cha, Je Seon Song, Jung‐Yul Cha, Kee‐Joon Lee, Kwang‐Mahn Kim, Jae‐Sung Kwon, Sung‐Hwan Choi
SJR Q1Journal of Periodontal ResearchOA

INTRODUCTION: Microbiome from a "healthy cohort" is used as a reference for comparison to cases and intervention. However, the studies with cohort-based clinical research have not sufficiently accounted for the multistability in oral microbial community. The screening is limited to phenotypic features with marked variations in microbial genomic markers. Herein, we aimed to assess the stability of the oral microbiome across time from an intervention-free "healthy" cohort. METHODS: We obtained 33

PeriodonticsDentistry
13
Article|5 citations·2021
Tomographic similarity scan with a computed modified absolute mandibular midsagittal plane for precise and objective localization of mandibular asymmetry
Utkarsh Mangal, Han Arum, Huisoo Kim, Yun-Hoa Jung, Kee‐Joon Lee, Hyung‐Seog Yu, Jae Joon Hwang, Sung‐Hwan Choi
SJR Q1Computers in Biology and MedicineOA
Oral SurgeryDentistry
14
Article|4 citations·2024
Integrating Phosphate Enhances Biomineralization Effect of Methacrylate Cement in Vital Pulp Treatment with Improved Human Dental Pulp Stem Cells Stimulation
Jeong‐Hyun Ryu, Utkarsh Mangal, Jae‐Sung Kwon, Ji‐Young Seo, Sung‐Yun Byun, Young‐Hee Lee, Sungil Jang, Geelsu Hwang, Hyemin Ku, Yooseok Shin, Dohyun Kim, Sung‐Hwan Choi
SJR Q1Advanced Healthcare MaterialsOA

Vital pulp treatment (VPT) is crucial for preserving the health and function of the tooth in cases where the pulp tissue remains vital despite exposure. Various materials are introduced for this purpose. However, challenges such as low strength, high solubility, and tooth discoloration persist. Methylmethacrylate-based cement (MC) offers excellent sealing ability, feasibility, and mechanical properties, making it a promising alternative for VPT. Phosphate-based glass (PBG) has the potential to p

Oral SurgeryDentistry
15
Article|4 citations·2021
Control of the occlusal plane in orthognathic surgery
Utkarsh Mangal, Jae Hyun Park, Sung‐Hoon Lim, Sung‐Kwon Choi, Jae-Hyun Sung, Jong‐Moon Chae
SJR Q2AJO-DO Clinical Companion
OrthodonticsDentistry

Research Areas

OrthodonticsOral SurgeryPeriodonticsBiomedical EngineeringMaterials ChemistryBiomaterials

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