Woojoong Kim
Seoul National University · 医学
研究室紹介
Professor Woojoong Kim's research lab specializes in interdisciplinary studies at the intersection of quantum physics, biomedical engineering, and clinical genetics. The lab investigates quantum phenomena in nanomechanical systems, such as vacuum-induced dissipation and photon detection via superradiant amplification, while also exploring rare genetic disorders like Blau syndrome and SYNGAP1-related neurodevelopmental conditions. Recent work includes translational applications in dermatology, such as photodynamic therapy for uncommon skin conditions, and population-level health studies on serum urate and mental health. The lab integrates advanced imaging, genomics, and biophotonics to address fundamental and clinical challenges in human disease and quantum technology.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15We propose an experiment for generating and detecting vacuum-induced dissipative motion. A high frequency mechanical resonator driven in resonance is expected to dissipate mechanical energy in quantum vacuum via photon emission. The photons are stored in a high quality electromagnetic cavity and detected through their interaction with ultracold alkali-metal atoms prepared in an inverted population of hyperfine states. Superradiant amplification of the generated photons results in a detectable ra
Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is an uncommon, benign dermatosis and is characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities. Various treatments, including topical steroids, topical calcipotriol, topical 5-fluorouracil, retinoid, cryotherapy, and carbon dioxide laser ablation have been tried for PEODDN, but the results were unsatisfactory. Recently, topical photodynamic therapy (PDT) has been shown to be effecti
Blau syndrome (BS) is a rare autosomal dominant, inflammatory syndrome that is characterized by the clinical triad of granulomatous dermatitis, symmetric arthritis, and recurrent uveitis. Mutations in the nucleotide oligomerization domain 2 (<i>NOD2</i>) gene are responsible for causing BS. To date, up to 30 Blau-associated genetic mutations have been identified within this gene. We report a novel <i>NOD2</i> genetic mutation that causes BS. A girl, aged 8 years, and her brother, aged 10 years,
BACKGROUND: Soluble urate has been shown to serve as an antioxidant, especially in the central nervous system. Although there are intriguing data suggesting that low levels of serum urate are associated with worse outcomes in neurodegenerative diseases, its impact on mental health has not been adequately assessed. Thus, we aimed to investigate the association between serum urate and depression using a large, nationally representative sample. METHODS: Information on participants' socio-demographi
The clinical and genetic characteristics of SYNGAP1 mutations in Korean pediatric patients are not well understood. We retrospectively analyzed 13 individuals with SYNGAP1 mutations from a longitudinal aspect. Clinical data, genetic profiles, and electroencephalography (EEG) patterns were examined. Genotypic analyses included gene panels and whole-exome sequencing. All patients exhibited global developmental delay from early infancy, with motor development eventually reaching independent ambulat
The dissipated power for FBAR devices that appears in the first paragraph on page 4 of our Letter [1] is based on the modulation depth of 10 9 and 10 3 kg=m 3 , rather than the reported values of 10 8 and 3:3 10 3 kg=m 3 , with all other parameters unchanged. The stated 10 W damage threshold holds for an FBAR device of surface area of 250 m 250 m. Since the threshold power is expected to scale proportionally to the surface area, a 1 cm 2 area FBAR device as considered in the discussion would suf
Our study is the first case series of <i>ATP1A3</i>-related disorders to be described in Korea and which further expands the understanding of its genotype-phenotype spectrum. A ketogenic diet showed no clear benefit for the patients with AHC.
Background: Although gout is accompanied by the substantial burden of kidney disease, there are limited data to assess renal function as a therapeutic target. This study evaluated the importance of implementing a “treat-to-target” approach in relation to renal outcomes. Methods: Patients with gout who underwent continuous urate-lowering therapy (ULT) for at least 12 months were included. The effect of ULT on renal function was investigated by means of a sequential comparison of the estimated glo
Background: The double-lumen cannula (DLC) has begun to be used worldwide for venovenous (VV) extracorporeal membrane oxygenation (ECMO). We aimed to examine whether the DLC could be an effective tool in the treatment of pediatric respiratory failure in Korea. Methods: We reviewed the records of patients weighing under 15 kg who underwent ECMO due to respiratory failure between January 2017 and December 2018. Outcomes of ECMO using a DLC and conventional ECMO using central method or 2 peripheral