Wooseong Do
Yonsei University · 医学
研究室紹介
Professor Wooseong Do's research lab specializes in orthopedic and musculoskeletal research, with a focus on shoulder disorders, particularly rotator cuff tears and glenohumeral instability. The lab investigates the clinical, radiological, and molecular mechanisms underlying shoulder pathology, including fatty infiltration in subscapularis tears, unrecognized shoulder subluxation, and the proteomic profiles of synovial fluid in rotator cuff disease. A key direction involves exploring the biological and genetic basis of tissue degeneration and repair, extending to podocyte injury in glomerular diseases, suggesting a broader interest in tissue fibrosis and cellular injury mechanisms.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
4PURPOSE: To compare arthroscopic repair without muscle advancement and open repair with muscle advancement in subscapularis tendon tears with fatty infiltration of Goutallier grade III or IV. METHODS: This study retrospectively investigated patients with subscapularis tears and advanced fatty infiltration of Goutallier grade III or IV between March 2009 and October 2022. Inclusion criteria were pre- and postoperative radiologic evaluation and a minimum of 2-year follow-up. Exclusion criteria inc
Rotator cuff tears are one of the most common shoulder disorders and can lead to pain, weakness, and limited mobility. Although the clinical condition has been widely studied, its molecular mechanisms are still not fully understood. In this exploratory study, we analyzed the proteomic profile of synovial fluid in patients with full-thickness rotator cuff tears and compared the results to those from a control group. Proteomic analysis was performed on synovial fluid samples from seven patients wi
Background: First-time anterior shoulder subluxation is typically diagnosed based on subjective instability or positive physical examination findings. However, some patients present without any perceived instability yet demonstrate definitive magnetic resonance imaging (MRI) findings such as Bankart or Hill-Sachs (HS) lesions. Purpose: To study the pathoanatomy of unrecognized subluxation with first-time dislocation and typical subluxation. Study Design: Cross-sectional study; Level of evidence,
Focal segmental glomerulosclerosis (FSGS) is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix. FSGS is classified as collapsing, tip, cellular, perihilar and not otherwise specified variants according to the location and character of the sclerotic lesion. Primary or idiopathic FSGS is considered to be related to podocyte injury, and the pathogenesis of podocyte injury has been actively investigated. Several circulating factors affecting podocy