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Wu Ying-Chieh

Seoul National University · 社会科学

研究室紹介

Professor Wu Ying-Chieh's research lab focuses on interdisciplinary biomedical and computational research, spanning neuro-oncology, microbial pathogenesis, and heterogeneous computing systems. The lab investigates molecular mechanisms in glioblastoma, particularly the role of interleukin-19 in immunosuppression and tumor recurrence, while also developing molecular diagnostics for pathogenic amoebae like Acanthamoeba. In parallel, the lab explores computational optimization for task and system mapping in heterogeneous computing environments, aiming to enhance performance in complex, distributed architectures. Additionally, the lab examines nutraceuticals and traditional herbal formulations for their neuroprotective and microbiome-modulating effects, especially in models of neurodevelopmental disorders.

glioblastomaAcanthamoebaheterogeneous computingnutraceuticalsmicrobiome modulation

Research Overview

Papers
28
Total Citations
62
Papers (5y)
15
Primary Field
社会科学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
15total
2019
2022
2023
2024
2025
Citations per year (5y)
29total
20192022202320242025

Selected Papers

15
1
Article|16 citations·2025
IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment
Gilbert Aaron Lee, Justin Bo‐Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung‐Hsiao Chiang, Wan-Yuo Guo, Chien‐Wei Wu, Liang-Wei Chen, Hung‐Wen Kao
SJR Q1Journal of Biomedical ScienceOA

Abstract Background Glioblastoma multiforme (GBM) is an aggressive brain tumor with chemoresistant, immunosuppressive, and invasive properties. Despite standard therapies, including surgery, radiotherapy, and temozolomide (TMZ) chemotherapy, tumors inevitably recur in the peritumoral region. Targeting GBM-mediated immunosuppressive and invasive properties is a promising strategy to improve clinical outcomes. Methods We utilized clinical and genomic data from the Taiwan GBM cohort and The Cancer

ImmunologyImmunology and Microbiology
2
Article|11 citations·2010
Evaluation of DNA extraction methods and dilution treatment for detection and quantification of Acanthamoeba in water and biofilm by real-time PCR
Ching‐Wen Chang, Ying-Chieh Wu
SJR Q2Water Science & Technology

Acanthamoeba, human pathogens and natural hosts of pathogenic bacteria, may be accurately detected and quantified by real-time PCR if Acanthamoeba DNA are properly extracted and PCR inhibitors are effectively eliminated. However, the optimization of DNA extraction methods has not been reported for Acanthamoeba. This study compared the effectiveness of two DNA extraction/purification methods (FastDNA(®) Spin Kit for soil and Wizard(®) SV genomic DNA Purification System) by using trophozoites and

EndocrinologyBiochemistry, Genetics and Molecular Biology
3
Article|10 citations·1995
Mapping Arbitrary Non-Uniform Task Graphs onto Arbitrary Non-Uniform System Graphs.
Song Chen, M.M. Eshaghian, Ying-Chieh Wu

this paper, a generic technique for clustering and mapping arbitrary task graphs onto arbitrary system graphs is presented. The task and system graphs studied in this paper have non-uniform computation and communication weights associated with the nodes and edges. The task graphs are directed graphs, while the system graphs are undirected. Using two clustering algorithms presented, a multi-level clustered graph called Spec graph can be obtained from a given task graph, and a multi-level clustere

Computer Networks and CommunicationsComputer Science
4
book|8 citations·2017
Property and Trust Law in Taiwan
Yun-Chieng Chang, Weitseng Chen, Ying Chieh Wu
Institutional Knowledge (InK) - Institutional Knowledge at Singapore Management University (Singapore Management University)OA
Political Science and International RelationsSocial Sciences
5
Article|7 citations·2022
KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring
Gilbert Aaron Lee, Hongwei Zhao, Yu-Wei Chang, Chia‐Jung Lee, Yu‐Chen S. H. Yang, Ying-Chieh Wu, Wanli Lin, Yun‐Ru Liu, De-Shan Ning, Sung‐Hui Tseng
SJR Q1Frontiers in PharmacologyOA

Mushrooms and Chinese traditional herbs have bioactive nutraceuticals with multiple therapeutic functions, including antioxidant and antibacterial activities and microbiome modulation properties. Mushroom-derived bioactive compounds are used in medicines for the treatment of neurological disorders with abnormal brain – gut – microbiome axis. This study examined the effects of KI Essence extract, a spleen-tonifying formula, on neurite growth, antioxidant activity, hypomyelination modulation, and

Social PsychologyPsychology
6
Article|6 citations·2024
CCN1 Is a Therapeutic Target for Reperfused Ischemic Brain Injury
Gilbert Aaron Lee, Yu‐Wei Chang, Jing-Huei Lai, Tzu‐Hao Chang, Shiu‐Wen Huang, Chih‐Hao Yang, Ting-An Shen, Wanli Lin, Ying-Chieh Wu, Li-Wen Tseng, Sung‐Hui Tseng, Yung-Chieh Chen
SJR Q1Translational Stroke Research
Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|3 citations·1997
Resource estimation for heterogeneous computing
M.M. Eshaghian, Ying-Chieh Wu
SJR Q1Future Generation Computer Systems
Computer Networks and CommunicationsComputer Science
8
Article|1 citations·2002
Scalable heterogeneous programming tools
Song Chen, M.M. Eshaghian, Richard F. Freund, Jerry L. Potter, Ying-Chieh Wu

We study the heterogeneous use of two programming paradigms for heterogeneous computing called Cluster-M and HAsC. Both paradigms can efficiently support heterogeneous networks by preserving a level of abstraction which does not include any architecture mapping details. Furthermore, they are both machine independent and hence are scalable. Unlike almost all existing heterogeneous orchestration tools which are MIMD based, HAsC is based on the fundamental concepts of SIMD associative computing. HA

Computer Networks and CommunicationsComputer Science
9
Article|0 citations·2023
An Investigation of Atmospheric Design Attributes in Light Food and Beverage Space Amidst Loneliness Economy Trend
Ying-Chieh Wu, Chia‐Hui Huang, Chun‐Chih Chen
Innovation on Design and CultureOA

In the loneliness economy era, the atmospheric design of light food and beverage spaces is particularly significant in meeting the multifaceted demands of urban consumers. Thus, we investigated how the atmospheric design of such spaces responds to and fulfills consumers’ multidimensional evaluations, encompassing their psychological, emotional, and social needs. The findings underscored the significant appeal of “emotional healing” and “emotional companionship” to consumers. The factor analysis

Social PsychologyPsychology
10
Article|0 citations·2011
Constructive trusts: A civilian approach
Ying Chieh Wu
Institutional Knowledge (InK) - Institutional Knowledge at Singapore Management University (Singapore Management University)OA
LawSocial Sciences
11
Article|0 citations·2011
Establishing three general requirements of the Doctrine of real subrogation under Korean Private Law
Ying Chieh Wu
Singapore Management University Institutional Knowledge (InK) (Singapore Management University)OA
Organizational Behavior and Human Resource ManagementBusiness, Management and Accounting
12
Article|0 citations·2012
Cancellation right of beneficiary under trust law: Call for possible paradigm shift
Ying Chieh Wu
Institutional Knowledge (InK) - Institutional Knowledge at Singapore Management University (Singapore Management University)OA
LawSocial Sciences
13
Article|0 citations·2023
A Comparative Study of Consumer Attitudes and Value for SDGs in Taiwan and China
Ying-Chieh Wu, Chia‐Hui Huang, Chun‐Chih Chen
International Journal of Business Studies and InnovationOA

This study aims to investigate the differences in Taiwanese and Chinese consumer attitudes and values toward products with SDG indicators. SDG indicators have been shared with a significant impact on future product design and corporate image globally, and products with them have gradually gained consumer attitudes. However, many companies have yet to realize the importance of products with SDG indicators for their marketing strategy for gaining the blue ocean and competitiveness. Sustainable dev

MarketingBusiness, Management and Accounting
14
Article|0 citations·2015
The dispute of Trust Property and its legal basis for the trustee's violation of the purpose of the trust
Ying Chieh Wu
Institutional Knowledge (InK) - Institutional Knowledge at Singapore Management University (Singapore Management University)OA
LawSocial Sciences
15
Article|0 citations·2022
Uncovering Hidden Fiduciaries in South Korean Private Law
Ying Chieh Wu
SJR Q2DOAJ (DOAJ: Directory of Open Access Journals)OA

This article attempts to extend the list of fiduciary relationship by unlocking some of the hidden fiduciaries in other areas of South Korean private law. The reason for this is as follows. The exact label of “fiduciary relationship” may not be widely used, but the underlying mechanisms can be found in many other legal relationships under South Korean private law. Through the clarification of the types of fiduciary relationship, even though it may not be complete, we can come to understand when

Political Science and International RelationsSocial Sciences

Research Areas

LawComputer Networks and CommunicationsMarketingEndocrinologyPolitical Science and International RelationsSocial Psychology

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