Yongsoo Kim
Hanyang University · 医学
研究室紹介
Professor Yongsoo Kim's research lab focuses on systems biology and biomedical engineering, with a strong emphasis on dynamic biological networks, computational systems biology, and medical imaging applications in liver and esophageal diseases. The lab integrates multi-omics data and advanced imaging techniques—such as shear wave elastography—to understand disease progression in cirrhosis and to develop non-invasive diagnostic tools. Additionally, the lab investigates fungal transcription factors and nuclear fuel characteristics, reflecting a multidisciplinary approach spanning molecular biology, bioinformatics, and nuclear engineering.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15OBJECTIVES: The purpose of this study was to investigate the diagnostic performance of shear wave elastography (SWE) for predicting the presence of esophageal varices and high-risk esophageal varices in patients with compensated cirrhosis and to compare it with other nonspecific predictors and according to the presence of splenomegaly. METHODS: Clinical data from 103 patients with compensated cirrhosis who underwent sonography, SWE, and endoscopy were collected consecutively. Liver stiffness was
During the last three decades, South Korean nuclear power plants have discharged about 5,950 tons of spent fuel and the maximum bum-up reached 55 GWd/MTU in 2002. This study was performed to support the development of Korean dry spent fuel storage alternatives. First, we chose V5H-17 × 17 and KSFA-16 × 16 as representative domestic spent fuels, considering current accumulation and the future generation of the spent fuels. Examination reveals that their average burn-ups have already increased fro
OBJECTIVES: To investigate the success rate of spleen stiffness measurement and factors that affect measurement success and to determine the spleen stiffness value of normal individuals by 2-dimensional shear wave elastography. METHODS: The spleen and liver stiffnesses of 313 consecutive patients were measured with SWE. The body mass index, abdominal wall thickness, spleen size, and liver stiffness of the patients were evaluated to identify factors associated with successful measurement of splee
The purpose of this study was to integrate leisure constraint theory and leisure facilitator theory and to suggest the Indicator of LPCT(Leisure Participation Condition Type). The reliability and validity of the Indicator of LPCT were confirmed using factor analysis. This study suggested 4 Leisure Participation Type : Facilitator condition, Partial facilitator condition, Partial constraint condition and Constraint condition. By LPCT, the present leisure activity and preferred leisure activity br
OBJECTIVES: To compare the diagnostic performance for advanced hepatic fibrosis measured by 2D shear-wave elastography (SWE), using either the coefficient of variance (CV) or the interquartile range divided by the median value (IQR/M) as quality criteria. METHODS: In this retrospective study, from January 2011 to December 2013, 96 patients, who underwent both liver stiffness measurement by 2D SWE and liver biopsy for hepatic fibrosis grading, were enrolled. The diagnostic performances of the CV
Paragonimus westermani is a lung fluke but may be found in organs other than the lungs. A case of omental paragonimiasis was found incidentally by plain radiography and computed tomography and showed multiple, irregularly shaped, conglomerated calcifications in the intraperitoneum. Many P. westermani ova were detected in the resected omentum. This uncommon calcification on the plain abdominal radiography and computed tomography scan was considered to represent radiologic findings of ectopic para
본 연구는 지난 30년간 관광학 안에서 축제에 대한 연구의 흐름을 살펴보고 현재 축제연구의 의미 고찰 및 향후 전망에 대한 연구이다. 관광학 분야 KCI 인용지수 상위 7개 저널에 1989년부터 2018년까지 30년간 게재된 482개의 논문을 대상으로 분석하였다. 내용분석 방법을 통해, 주제별, 연도별, 연구기여도 3가지의 관점에서 그 흐름과 동향을 살펴보았다. 연구주제 구분은 체계론적 관점을 인용해, 축제 참가자 개인에게 초점을 맞춘 ‘미시적 연구’, 사회조직으로서 축제관련 조직 및 특성에 대한 ‘중시적 연구’, 축제를 둘러싼 환경인 정치, 경제, 사회, 문화적 영향을 다룬 ‘거시적 연구’로 구분해서 살펴보았다. 연도별로는 ‘태동기(1989~1996)’, ‘도약기(1997~2004)’, ‘발전기(2005~2010)’, ‘성찰기(2011~현재)’의 네 시기로 구분하여 각 시대의 주요 특징과 의미를 살펴보았다. 연구기여도 측면에서는 각 논문을 후속 연구에서 인용한 횟수를 정리한 인용지
We recently isolated a few mammalian homologue of Drosophila lethal giant larvae (lgl) recessive oncogene, suggesting that there is functional conservation among proteins of this family. The comparison of amino acid sequence for mgl-1 with other lgl family members using the clustal method showed that they are highly homologous. Therefore, we investigated the biological function of mgl-1, a mouse orthologue of lgl, in the absence of Saccharomyces cerevisiae Sop1 and Sop2, the yeast homologues of
Radiolysis of chemical agents occurs during the decontamination of nuclear power plants. The γ-ray irradiation tests of the N2H4–Cu+–HNO3 solution, a decontamination agent, were performed to investigate the effect of Cu+ ion and HNO3 on N2H4 decomposition using a Co-60 high-dose irradiator. After the irradiation, the residues of N2H4 decomposition were analyzed by Ultraviolet-visible (UV) spectroscopy. NH4+ ions generated from N2H4 radiolysis were analyzed by ion chromatography. Based on the res