Young-suk Lee
Korea Advanced Institute of Science and Technology
研究室紹介
Professor Young-suk Lee's research lab specializes in computational genetics and bioinformatics, focusing on the development of simulated genetic variant databases for non-model and endangered species. The lab creates pseudo-databases—such as stevia pseudoDB, komodo dragon pseudoDB, and swan goose pseudoDB—using in silico methods to model genetic diversity where real genomic data is limited. These databases support evolutionary studies, conservation genetics, and the design of molecular markers for species-specific research. The lab also compares variant sets derived from public resources like dbSNP with those generated from their simulated PseudoDB frameworks to evaluate genetic variation patterns.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15A simulated database of stevia genetic variants, designated as stevia pseudoDB.
(*) Overview This repository provides genomic resources for genetic variant discovery. Utilizing the GATK pipeline, we offer a standardized, modular, and fully reproducible framework that transforms raw Next-Generation Sequencing (NGS) data into high-quality Variant Call Format (VCF) datasets. Our goal is to facilitate genomic research and promote the principles of open data sharing. For each species, the repository includes: ✔ pseudoDB: A simulated database of genetic variants. ✔ dbSNP_variant_
A simulated database of komodo dragon genetic variants, designated as komodo dragon pseudoDB.
Two sets of genetic variants: one based on dbSNP and the other on the PseudoDB.
(*) Overview This repository provides genomic resources for genetic variant discovery. Utilizing the GATK pipeline, we offer a standardized, modular, and fully reproducible framework that transforms raw Next-Generation Sequencing (NGS) data into high-quality Variant Call Format (VCF) datasets. Our goal is to facilitate genomic research and promote the principles of open data sharing. For each species, the repository includes: ✔ pseudoDB: A simulated database of genetic variants. ✔ dbSNP_variant_
A simulated database of swan goose genetic variants, designated as swan goose pseudoDB.
A set of genetic variants based on the PseudoDB.
A simulated database of african oil palm genetic variants, designated as african oil palm pseudoDB.
A simulated database of african oil palm genetic variants, designated as african oil palm pseudoDB.
A set of genetic variants based on the PseudoDB.
A simulated database of stevia genetic variants, designated as stevia pseudoDB.
Two sets of genetic variants: one based on dbSNP and the other on the PseudoDB.
A set of genetic variants based on the PseudoDB.
Two sets of genetic variants: one based on dbSNP and the other on the PseudoDB.
Two sets of genetic variants: one based on dbSNP and the other on the PseudoDB.