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Young-sung Kim

Korea University · 医学

研究室紹介

Professor Young-sung Kim's research lab specializes in anesthesiology and perioperative medicine, with a focus on optimizing airway management, enhancing neurological protection during hypoxic stress, and improving anesthetic safety in vulnerable patient populations. The lab investigates novel anesthetic techniques such as total intravenous anesthesia (TIVA) and neuromuscular blockade reversal using sugammadex in patients with organ dysfunction, particularly renal and hepatic impairment. It also explores neuroprotective agents like magnesium L-threonate to mitigate cognitive decline following hypoxic injury, combining in vitro, in vivo, and clinical study approaches.

anesthesianeuroprotectionhypoxiasugammadexTIVA

Research Overview

Papers
70
Total Citations
601
Papers (5y)
12
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2022
2023
2024
2025
2026
Citations per year (5y)
53total
20222023202420252026

Selected Papers

15
1
Review|23 citations·2020
Different classes of videoscopes and direct laryngoscopes for double-lumen tube intubation in thoracic surgery: A systematic review and network meta-analysis
Young Sung Kim, Ji‐Hyun Song, Byung Gun Lim, Il Ok Lee, Young Ju Won
SJR Q1PLoS ONEOA

Most videoscopes improved the success rate of double-lumen tube intubation; however, they were time-consuming (except videostylet) and had a higher malposition rate than the direct laryngoscope.

Anesthesiology and Pain MedicineMedicine
2
Article|22 citations·2020
Neuroprotective effects of magnesium l-threonate in a hypoxic zebrafish model
Young Sung Kim, Young Ju Won, Byung Gun Lim, Too Jae Min, Yeon-Hwa Kim, Il Ok Lee
SJR Q2BMC NeuroscienceOA

Abstract Background Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in the brain closely related to cognitive function) into brain cells, and the initial response of cells to cortical hypoxia depends on glutamate. Previous studies have suggested that magnesium may have protective effects against hypoxic injuries. In particular, magnesium l -threonate (MgT) may increase magnesium ion concentrations in the brain better than MgSO 4 and improve cognitive function. Methods We evalu

Cellular and Molecular NeuroscienceNeuroscience
3
Article|22 citations·2019
<p>Lung ultrasound score-based perioperative assessment of pressure-controlled ventilation-volume guaranteed or volume-controlled ventilation in geriatrics: a prospective randomized controlled trial</p>
Young Sung Kim, Young Ju Won, Dong Kyu Lee, Byung Gun Lim, Heezoo Kim, Il Ok Lee, Jin Hee Yun, Myoung Hoon Kong
SJR Q1Clinical Interventions in AgingOA

This study was registered at the UMIN clinical trials registry (unique trial number: UMIN000029355; registration number: R000033510).

Critical Care and Intensive Care MedicineMedicine
4
Review|18 citations·2021
Efficacy and Safety of Sugammadex for the Reversal of Rocuronium-Induced Neuromuscular Blockade in Patients with End-Stage Renal Disease: A Systematic Review and Meta-Analysis
Young Sung Kim, Byung Gun Lim, Young-Ju Won, Seok Kyeong Oh, Jung-Suk Oh, Soo-Ah Cho
SJR Q2MedicinaOA

Background and Objectives: Sugammadex is widely used in anesthesia to reverse rocuronium-induced neuromuscular blockade (NMB). In patients with compromised kidney function, most drugs show alteration of their pharmacokinetic profile with reduced clearance. The purpose of this article is to examine the efficacy, pharmacokinetics, and safety of sugammadex in end-stage renal disease (ESRD) patients receiving general anesthesia, using a systematic review. Materials and Methods: The databases of PubM

Anesthesiology and Pain MedicineMedicine
5
Article|16 citations·2020
<p>Comparison of the Postoperative Liver Function Between Total Intravenous Anesthesia and Inhalation Anesthesia in Patients with Preoperatively Elevated Liver Transaminase Levels: A Retrospective Cohort Study</p>
Seok Kyeong Oh, Byung Gun Lim, Young Sung Kim, Seong Shin Kim
SJR Q1Therapeutics and Clinical Risk ManagementOA

TIVA may be safer for patients with preoperatively elevated liver transaminase levels.

Developmental NeuroscienceNeuroscience
6
Article|13 citations·2018
Unusual elevation in Entropy but not in PSI during general anesthesia: a case report
Young Sung Kim, Dongik Chung, Seok Kyeong Oh, Young Ju Won, Il Ok Lee
SJR Q1BMC AnesthesiologyOA

BACKGROUND: EEG monitoring is useful for determining an adequate level of anesthesia. However it is sometimes interfered by various reasons. We describe a case in which we successfully confirmed the adequate depth of anesthesia by monitoring the patient state index (PSI), which was computed from the SedLine monitor data in Root (Masimo) during general anesthesia. Our case showed unusual elevations in entropy, but not in PSI. CASE PRESENTATION: A 34-year-old woman was scheduled for emergency surg

Anesthesiology and Pain MedicineMedicine
7
Article|13 citations·2018
Sugammadex affects emergence agitation in children undergoing strabismus surgery
Young Sung Kim, Young Sung Kim, Jae Ryung, Yoon Sook Lee, Woon Young Kim, Jae Hwan Kim, Yun Hee Kim, Yun Hee Kim
SJR Q3Journal of International Medical ResearchOA

Objective Emergence agitation (EA) has a multifactorial origin, and the effect of sugammadex on EA has not been established. We investigated the effect of sugammadex on EA incidence and severity. Methods We performed a retrospective study of children aged 1 to 13 years who underwent strabismus surgery. Patients received sugammadex or conventional neuromuscular reversal agents. The primary outcome variables were EA incidence and severity. Secondary outcome variables were postoperative fentanyl us

Anesthesiology and Pain MedicineMedicine
8
Article|10 citations·2015
Effects of propofol or desflurane on post‐operative spirometry in elderly after knee surgery: a double‐blind randomised study
Young Sung Kim, Byung Gun Lim, Hye Jin Kim, Myoung Hoon Kong, Il Ok Lee
SJR Q2Acta Anaesthesiologica Scandinavica

BACKGROUND: Intravenous or volatile agents reduce respiratory function, which can result in respiratory complications in geriatric patients. We hypothesised that there would be no differences in lung function between anaesthesia established using either drug. METHODS: Elderly patients were randomly assigned to receive either propofol with remifentanil (n = 48) or desflurane (DES) with remifentanil (n = 52) for knee surgery. Spirometry tests including forced expiratory volume in 1 s (FEV1 ), forc

Pulmonary and Respiratory MedicineMedicine
9
Article|10 citations·2014
Combined spinal-epidural anesthesia for lumbar discectomy in a patient with asymptomatic severe aortic stenosis: a case report
Young Sung Kim, Ji‐Hye Park, Shin Young Lee, Byung Gun Lim, Heezoo Kim, Il Ok Lee, Myoung-Hoon Kong
SJR Q1Korean journal of anesthesiologyOA

The use of neuraxial anesthesia has traditionally been contraindicated in patients with severe aortic stenosis. However, general anesthesia can be riskier than neuraxial anesthesia for severe aortic stenosis patients undergoing spinal surgeries in the prone position as this can cause a major reduction in cardiac output secondary to diminished preload. In addition, general anesthesia, muscle relaxation, and positive-pressure ventilation can decrease venous return and reduce vascular tone, further

SurgeryMedicine
10
Article|9 citations·2016
The protective effect of hydromorphone to ischemia in rat glial cells
Young Sung Kim, Woon Young Kim, Yeon-Hwa Kim, Ji Won Yoo, Too Jae Min
SpringerPlusOA

BACKGROUND: Ischemic insults during operation can cause ischemic-reperfusion injuries in brain as well as memory impairments. Total intravenous anesthesia (TIVA) is the preferred anesthetic method in brain surgery, as it utilizes motor evoked potential monitoring. And the use of opioids is common in TIVA. However there are few studies about ischemic protective effect of opioids to glial cells. METHODS: We used mixed cultures of rat glial cells, which were harvested from the brain of 1-day old ra

Pathology and Forensic MedicineMedicine
11
Article|8 citations·2021
Comparison of the effects of dexmedetomidine and remifentanil on perioperative hemodynamics and recovery profile of patients undergoing laryngeal microsurgery
Young Sung Kim, Hae Wone Chang, Heezoo Kim, Jongsun Park, Young Ju Won
SJR Q3MedicineOA

BACKGROUND: Laryngeal microsurgery (LMS) causes hemodynamic instability and postoperative agitation, cough, pain, nausea, and vomiting. Moreover, because of a short operation time, it is associated with challenging anesthetic management. The aim of this study was to compare the usefulness of continuous administration of dexmedetomidine and remifentanil in inducing general anesthesia in patients undergoing LMS. METHODS: This is a prospective randomized control design. Continuous intravenous infus

Anesthesiology and Pain MedicineMedicine
12
Article|7 citations·2019
A Comparison of Bispectral Index and Entropy During Sevoflurane Anesthesia Induction in Children with and without Diplegic Cerebral Palsy
Young Sung Kim, Young Ju Won, Hyerim Jeong, Byung Gun Lim, Myoung Hoon Kong, Il Ok Lee
SJR Q2EntropyOA

BACKGROUND: This study compared the correlation of bispectral index (BIS) or entropy with different sevoflurane concentrations between children with and without cerebral palsy (CP) during induction. METHODS: For eighty-two children (40 CP and 42 non-CP children), anesthesia was induced with sevoflurane. BIS and entropy (response entropy and state entropy (RE and SE)) were recorded before and after the induction of anesthesia at end-tidal sevoflurane concentrations of 1-3 vol%. The sedation statu

Anesthesiology and Pain MedicineMedicine
13
letter|5 citations·2014
False Elevation of Bispectral Index With a Mandibular Position in a Patient Undergoing Craniotomy
Young Sung Kim, Byung Gun Lim, Il Ok Lee
SJR Q2Journal of Neurosurgical Anesthesiology

Department of Anesthesiology and Pain Medicine, Guro Hospital, College of Medicine, Korea University, Seoul, Korea The authors have no funding or conflicts of interest to disclose.

Anesthesiology and Pain MedicineMedicine
14
Article|4 citations·2014
Acute Calcific Tendinitis of the Flexor Digitorum Superficialis of the Finger: A Case Report
Young Sung Kim, Ho Min Lee, Jong Pil Kim
Open Journal of OrthopedicsOA

Acute calcific tendinitis of the shoulder is a well-known condition, but it is rare in the hand or finger. It is often misdiagnosed when it occurs outside the shoulder. We report an unusual case of acute calcific tendinitis of the flexor digitorum superficialis insertion of the 4th finger in a young female martial art athlete after minor trauma history, and discuss with a review of the literature.

SurgeryMedicine
15
Article|3 citations·2016
Assessment of chloral hydrate-centered pediatric sedation performed by non-anesthesiologists
Young Sung Kim, Byung Gun Lim, Sung Wook Kang, So Hyun Lee, Won Joon Lee, Il Ok Lee
SJR Q2Anesthesia and Pain MedicineOA

Background: We aimed to evaluate the efficacy and safety of chloral hydrate-based pediatric sedation conducted by non- anesthesiologists. Methods: The design and setting of this study was a single-center retrospective study performed at a tertiary university hospital between July 2012 and May 2013. A total of 519 children were enrolled in this study. We investigated the sedation medication, age of patients and type of diagnostic tests or procedures and evaluated the success rate of sedation, sed

Anesthesiology and Pain MedicineMedicine

Research Areas

Anesthesiology and Pain MedicineSurgeryPhysiologyCritical Care and Intensive Care MedicineEpidemiologyPulmonary and Respiratory Medicine

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