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Youngmok Sim

Sungkyunkwan University · 医学

研究室紹介

Professor Youngmok Sim's research lab specializes in thoracic and cardiothoracic diseases, with a strong focus on pulmonary and mediastinal tumors, including thymic epithelial tumors and nontuberculous mycobacterial lung disease. The lab investigates the radiological and clinical predictors of disease progression and treatment outcomes, particularly through advanced imaging techniques such as high-resolution CT and MRI. It also explores environmental risk factors, such as long-term air pollution exposure, in relation to lung cancer incidence. The lab integrates clinical, radiological, and pathological data to improve diagnostic accuracy and surgical decision-making.

thymic tumorsNTM lung diseaselung cancerradiological predictorsair pollution and lung cancer

Research Overview

Papers
100
Total Citations
554
Papers (5y)
19
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
19total
2021
2022
2023
2024
2025
Citations per year (5y)
11total
20212022202320242025

Selected Papers

15
1
Article|205 citations·2004
Does CT of Thymic Epithelial Tumors Enable Us to Differentiate Histologic Subtypes and Predict Prognosis?
Yeon Joo Jeong, Kyung Soo Lee, Young Tae Kim, Young Mok Shim, Jungho Han, Oh‐Jung Kwon
SJR Q1American Journal of Roentgenology

Although CT is of limited value in differentiating histologic subtypes according to the WHO classification, CT findings may serve as predictors of postoperative recurrence or metastasis for the thymic epithelial tumors.

NeurologyMedicine
2
Article|48 citations·2017
Lung Cancer Risk and Residential Exposure to Air Pollution: A Korean Population-Based Case-Control Study
디르가, 김환철, 최창민, 신명희, 심영목, 임종한, 유정선, 남해성, 박성민
https://www.eymj.org/DOIx.php?id=10.3349/ymj.2017.58.6.1111

Purpose: To investigate the association between long-term exposure to ambient air pollution and lung cancer incidence in Koreans. Materials and Methods: This was a population-based case-control study covering 908 lung cancer patients and 908 controls selectedfrom a random sample of people within each Korean province and matched according to age, sex, and smoking status. We developed land-use regression models to estimate annual residential exposure to particulate matter (PM10) and nitrogen dioxi

3
Article|33 citations·2008
Surgical Treatment of Pulmonary Diseases Due to Nontuberculous Mycobacteria
고원중, Yee Hyung Kim, 권오정, 최용수, 김관민, 심영목, 김진국
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120080230030397

Although the treatment of pulmonary diseases due to nontuberculous mycobacteria (NTM) requires the long-term use of antibiotics in combination, the treatment success rates are unsatisfactory. We evaluated the clinical characteristics and surgical outcomes of 23 patients with NTM lung diseases who had underwent pulmonary resection. The median age of the patients was 45 yr. Of the 23 patients, 10 had Mycobacterium avium-intracellulare complex infection, 12 had M. abscessus infection, and one had M

4
Article|31 citations·2009
Malignant Pure Pulmonary Ground-Glass Opacity Nodules: Prognostic Implications
박종헌, 이경수, 김지혜, 심영목, 최용수, 이진아, 김진국

Objective: This study was designed to evaluate follow-up results in terms of patient prognosis for malignant pulmonary nodules depicted as pure groundglass opacity (GGO) lesion observed at high-resolution CT (HRCT). Materials and Methods: Surgical removal for malignant GGO nodules was accomplished in 58 patients (26 men, 32 women; mean age, 57 years; age range, 29-78 years). Patient prognoses were assessed by patient clinical status and the presence of changes in nodule size determined after a f

5
Article|30 citations·2007
Chronic Expanding Hematoma of the Thorax
Yong Soo Kwon, Won‐Jung Koh, Taesung Kim, Kyung Soo Lee, Byung‐Tae Kim, Young Mok Shim
SJR Q2Yonsei Medical JournalOA

We report the first case in Korea of a chronic expanding hematoma, which presented as a huge mass in the pleural cavity. A 67-year-old woman exhibiting a slowly-expanding intrathoracic mass, as revealed by a chest radiograph, was admitted to our hospital. The patient had undergone a pneumonectomy 37 years earlier during treatment for pulmonary tuberculosis. Computed tomography revealed a huge mass in her right hemithorax. The differential diagnosis of this mass included chronic empyema combined

SurgeryMedicine
6
Article|22 citations·2003
Thymic Epithelial Tumors Classified According to a Newly Established WHO Scheme: CT and MR Findings
한정호, 이경수, 이진아, 김태성, 심영목, 김진국, 김관민, 권오정

Thymic epithelial tumor is a distinctive pathologic entity exhibiting variable histologic features and heterogeneous oncologic behavior. Among the various classification systems, that of the World Health Organization has been adopted because of good correlation between histologic appearance and oncologic behavior. Radiologically, a smooth contour and round shape are most suggestive of a type-A tumor, whereas an irregular contour most strongly suggests type C. Pleural seeding is rare in type-A an

7
Article|21 citations·2002
The Spectrum of Benign Esophageal Lesions: Imaging Findings
KyungMiJang, 이경수, 이순진, EunAKim, 김태성, DaeheeHan, 심영목

Benign esophageal lesions occur in various diseases. Barium studies are useful for the evaluation of mucosal surface lesions but provide little information about the extramucosal extent of disease. Computed tomography and magnetic resonance imaging, on the other hand, permit the assessment of wall thickness, mediastinal involvement, adjacent lymphadenopathy, and distant spread. In diseases such as fibrovascular polyps, duplication cysts, scleroderma, trauma, caustic esophagitis, hiatal hernia, e

8
Article|19 citations·2008
18F-FDG PET versus 18F-FDG PET/CT for Adrenal Gland Lesion Characterization: a Comparison of Diagnostic Efficacy in Lung Cancer Patients
Yon Mi Sung, 이경수, 김병태, 최준영, 정명진, 심영목, 이진아, 김태성

Objective: The aim of this study was to assess the diagnostic efficacy of integrated PET/CT using fluorodeoxyglucose (FDG) for the differentiation of benign and metastatic adrenal gland lesions in patients with lung cancer and to compare the diagnostic efficacy with the use of PET alone. Materials and Methods: Sixty-one adrenal lesions (size range, 5 104 mm; mean size, 16 mm) were evaluated retrospectively in 42 lung cancer patients. Both PET images alone and integrated PET/CT images were assess

9
Article|17 citations·2001
In vitro establishment of cis-diammine-dichloroplatinum(II) resistant lung cancer cell line and modulation of apoptotic gene expression as a mechanism of resistant phenotype
Sung-Soo Yoon, Kwang-Sung Ahn, Sun-Hee Kim, Young Mok Shim, Jhingook Kim
SJR Q1Lung Cancer
OncologyMedicine
10
Article|15 citations·2012
High Dose Involved Field Radiation Therapy as Salvage for Loco-Regional Recurrence of Non-Small Cell Lung Cancer
배선현, 안용찬, 남희림, 박희철, 표홍렬, 심영목, 김진국, Kwhanmien Kim, 안진석, 안명주, 박근칠
http://www.eymj.org/DOIx.php?id=10.3349/ymj.2012.53.6.1120

Purpose: To determine the effectiveness of salvage radiation therapy (RT) in patients with loco-regional recurrences (LRR) following initial complete resection of non-small cell lung cancer (NSCLC) and assess prognostic factors affecting survivals. Materials and Methods: Between 1994 and 2007, 64 patients with LRR after surgery of NSCLC were treated with high dose RT alone (78.1%) or concurrent chemo-radiation therapy (CCRT, 21.9%) at Samsung Medical Center. Twenty-nine patients (45.3%) had loca

11
Article|13 citations·2007
Chronic Expanding Hematoma of the Thorax
권용수, 고원중, 김태성, 이경수, 김병태, 심영목
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120070480020337

We report the first case in Korea of a chronic expanding hematoma, which presented as a huge mass in the pleural cavity. A 67-year-old woman exhibiting a slowly-expanding intrathoracic mass, as revealed by a chest radiograph, was admitted to our hospital. The patient had undergone a pneumonectomy 37 years earlier during treatment for pulmonary tuberculosis. Computed tomography revealed a huge mass in her right hemithorax. The differential diagnosis of this mass included chronic empyema combined

12
Article|10 citations·2008
FDG PET/CT and Mediastinal Nodal Metastasis Detection in Stage T1 Non-Small Cell Lung Cancer: Prognostic Implications
신경민, 이경수, 심영목, 김진국, 김병태, 권오정, 박근칠

Objective: We aimed to compare the prognoses of patients with pathologically true negative (P-TN) N2 and PET/CT false negative (FN) results in stage T1 nonsmall cell lung cancer (NSCLC). Materials and Methods: Our institutional review board approved this retrospective study with a waiver of informed consent. The study included 184 patients (124 men and 60 women; mean age, 59 years) with stage T1 NSCLC who underwent an integrated PET/CT and surgery. After estimating the efficacy of PET/CT for det

13
Article|7 citations·2015
Prediction of Pathologic Grade and Prognosis in Mucoepidermoid Carcinoma of the Lung Using 18F-FDG PET/CT
박병준, 김홍관, 최용수, 김진국, 조재일, 최준영, 심영목

The maximum standardized uptake value (SUVmax) of pulmonary mucoepidermoid carcinoma (PMEC) in fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) was evaluated as a preoperative predictor of pathologic grade and survival rate. Twenty-three patients who underwent preoperative PET/CT and complete resection for PMEC were enrolled. The optimal cut-off SUVmax for tumor grade was calculated as 6.5 by receiver operating characteristic curve. The patients we

14
Article|7 citations·2006
Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection
Hyoung Soo Kim, 이호석, 최용수, 김관민, 심영목, 김진국
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120060210020224

We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery was 25.4+/-15.1 months for the definite 2nd primary lung cancer (n=20) and 8.9+/-5.7 months for metastatic lung cancer (n=9). The procedures at the second operations were completion-pneumonectomy in 11

15
Article|6 citations·2005
Prognosis After Surgical Resection of M1a/M1b Esophageal Squamous Cell Carcinoma
심영목, 최용수, 김관민
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120050200020229

This study was undertaken to examine prognosis after resection for M1 disease in squamous cell esophageal carcinoma. Fifty-six patients with M1 esophageal cancer underwent esophageal resection with two or three-field nodal dissection from 1994 to 2001. Operative mortality occurred in 3 patients. Primary tumor sites were as fol-lows; 10 upper, 23 middle, and 20 lower thoracic esophagus. They were found to have M1 disease by pathologic examination of dissected nodes, 24 M1a and 29 M1b. Forty-two p

Research Areas

NeurologySurgeryOncologyInformation SystemsPulmonary and Respiratory Medicine

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