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Youngseon Park

Hanyang University · 医学

研究室紹介

Professor Youngseon Park's research lab focuses on interdisciplinary studies spanning biomedical sciences, drug discovery, and computer systems engineering. The lab investigates cellular phone addiction and psychosocial factors in adolescents, explores enzymatic macrocyclization for novel peptide-based therapeutics, and examines thrombosis mechanisms in preclinical models. Additionally, the lab contributes to systems-level performance characterization of storage technologies, particularly hard disk drives, through innovative tool development. These diverse research directions reflect a strong commitment to both health-related innovation and advanced technological analysis.

cellular phone addictioncyclic peptidesthrombosis modeldisk characterizationATP-grasp enzyme

Research Overview

Papers
28
Total Citations
300
Papers (5y)
7
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
7total
2012
2017
2021
2022
2023
Citations per year (5y)
93total
20122017202120222023

Selected Papers

15
1
Article|138 citations·2005
청소년의 휴대폰 중독성향의 예측모형
양심영, 박영선

This study investigated firstly the cellular phone addiction tendency according to the classification of addiction, dependency, non-addiction and predicting factors of cellular phone use and secondly the psycho-social characteristics of cellular phone use by adolescents?. Participants were 368 students of academic and occupational high schools in Seoul. A prediction model of cellular phone addiction tendency was developed and showed that there were significant effects of cellular phone use-time,

2
Article|45 citations·2017
Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats
Hyunbin Lee, Youngseon Park, Seokhee Kim
SJR Q1BiochemistryOA

Macrocyclization of peptides is often employed to generate novel structures and biological activities in the biosynthesis of natural products and drug discovery. The enzymatic cross-linking of two side chains in a peptide via an ester or amide has a high potential for making topologically diverse cyclic peptides but is found with only a single consensus sequence in the microviridin class of natural products. Here, we report that a peptide with a new sequence pattern can be enzymatically cross-li

PharmacologyMedicine
3
Article|26 citations·2021
Characterization of Ferric Chloride-Induced Arterial Thrombosis Model of Mice and the Role of Red Blood Cells in Thrombosis Acceleration
Yeseul Shim, Il Kwon, Youngseon Park, Heow Won Lee, Jayoung Kim, Young Dae Kim, Hyo Suk Nam, Sungha Park, Ji Hoe Heo
SJR Q2Yonsei Medical JournalOA

PURPOSE: )-induced thrombosis model is widely used for thrombosis research. However, it lacks standardization with uncertainty in the exact mechanism of thrombosis. This study aimed to characterize thrombus formation in a mouse model. MATERIALS AND METHODS: -induced thrombosis model. We also investigated thrombus histopathology using immunohistochemistry and electron microscopy. RESULTS: treatment area. Transmission electron microscopy showed that RBCs attached to and were surrounded by aggregat

HematologyMedicine
4
Article|23 citations·2010
재가노인의 일상활동 어려움, 악력, 일상생활동작이 주관적 건강에 미치는 영향
홍귀령, 이윤경, 박영선, 오은미

Purpose: The purpose of the study was to examine the predictive relationships between predictors [(difficulty on daily activities due to arthritis, falls, and pain, grip strength, and activities of daily living (ADLs)], and perceived health in community-living older adults in Korea. Method: A descriptive, cross‐sectional survey design was used. Data were obtained from Korean Longitudinal Study of Ageing conducted in 2006. A stratified sample was selected of 5,545 older adults who were over 60 ye

5
Article|13 citations·2006
고령 산모의 임신 및 출산의 임상적 특성에 관한 메타분석
최재호, 한현주, 황정혜, 정성노, 문형, 박문일, 차경준, 최항석, 오재응, 박영선

=목적: 35세 또는 40세 이상의 고령 산모에서 연령 및 연령과 관련된 산전 및 산후 합병증의 위험정도를 알아보고자 하였다.연구 방법: 1996년 이후 국내에서 발표된 35세 또는 40세 이상의 고령 산모에 대한 7편의 연구문헌에 대해 메타 분석을 실시하였다.결과: 35세 또는 40세 이상의 고령 산모에 있어서 출산 후 산모 및 신생아 상태는 전반적으로 양호하였다. 그러나, 연구군에서 대조군에 비해 임신 중에 임신 합병증 (조기분만, 태위, 임신성 고혈압, 임신성 당뇨병, 전치 태반, 조기 양막파수)과 자궁 근종, 출산 후 저체중아에 있어서 통계적으로 의의있게 높은 빈도를 보였다.

6
Article|11 citations·2008
DIG: Rapid Characterization of Modern Hard Disk Drive and Its Performance Implication
Jongmin Gim, Youjip Won, Jaehyeok Chang, Junseok Shim, Youngseon Park

In this work, we develop novel disk characterization suite, DIG (disk geometry analyzer), which allows us to rapidly extract and to characterize the key performance metric of modern hard disk drive. Development of this tool is accompanied by thorough examination of four off-the-shelf hard disk drives. DIG consists of three key ingredients: O(1) track boundary detection algorithm,O (log n) zone boundary detection algorithm, and hybrid sampling based seek time profiling. We particularly focus on a

Computer Networks and CommunicationsComputer Science
7
Article|9 citations·2021
Effect of leukopenia induced by cyclophosphamide on the initial stage of arterial thrombosis in mice
Kee Ook Lee, Il Kwon, Hyo Suk Nam, Youngseon Park, Jayoung Kim, Yeseul Shim, Zolzaya Erdenebileg, Myoung Jin, Hyun-Jung Choi, Hye‐Yeon Choi, Jaewoo Song, Ji Hoe Heo
SJR Q2Thrombosis ResearchOA
ImmunologyImmunology and Microbiology
8
Article|7 citations·2005
지역의 산업구조와 연령구조의 연관성 및 영향력 분석
노정현, 박영선, 김태균, 김재진

With moving of the main of industrial structure from primary industry to secondary and tertiary industries, population concentration to large metropolitans is being accelerated. Korean government executes a plan to rearrange industries at undeveloped regions. This industry rearrange plan will change the structure of industry in each region, and therefore, age structure in each region will also be changed. Accordingly, it is needed to expect the age structure of population which is changed with c

9
Article|6 citations·2022
Effects of Interleukin-17A on the Early Stages of Arterial Thrombosis in Mice
Youngseon Park, Yeseul Shim, Il Kwon, Heow Won Lee, Hyo Suk Nam, Hyun-Jung Choi, Ji Hoe Heo
SJR Q2Yonsei Medical JournalOA

Purpose: Interleukin (IL)-17A has been suggested to play a role in the growth and organization of thrombi. We examined whether IL-17A plays a role in the early stages of thrombosis and whether there are sex differences in the effects of IL-17A. Materials and Methods: We performed a blinded, randomized, placebo-controlled study to compare time to thrombotic occlusion and sex differences therein between mice treated with IL-17A and those treated with saline using a ferric chloride-induced model. W

ImmunologyImmunology and Microbiology
10
Article|6 citations·2004
오개념 진단 및 교정을 위한 규칙장 모델의 알고리즘 개발
김성훈, 박영선

1980년대 초반부터 계속적으로 미국의 측정학계에 소개되어 온 규칙장 모형(Rule Space Model: RSM)은 앞으로 학생들의 인지과정을 진단하기 위한 측정이론이다. 그 진단은 후속적으로 교정학습을 위한 직접적인 지침이 될 수 있다. 이에 본 연구에서는 규칙장 모형의 논리에 근거하여 인지과정의 진단을 가능하게 하는 알고리즘을 개발하고, 모의실험을 통해 이를 적용하여 보았다.

11
Article|5 citations·2023
Association of clot ultrastructure with clot perviousness in stroke patients
Young Dae Kim, Il Kwon, Youngseon Park, Hyungwoo Lee, Il Hyung Lee, In Hwan Lim, Soon-Ho Hong, Hye Sun Lee, Hyo Suk Nam, Ji Hoe Heo
SJR Q1Scientific ReportsOA

Clot perviousness on computerized tomography (CT) is predictive of response to reperfusion therapy. This study aimed to determine the association of clot perviousness with ultrastructural features of clot in stroke patients undergoing endovascular thrombectomy. We quantitatively analyzed the ultrastructural components identified using scanning electron microscopy. The clot components were determined in the inner portions of the clots. Clot perviousness was assessed as thrombus attenuation increa

EpidemiologyMedicine
12
Article|3 citations·2010
디자인 특성에 따른 니트 패션 트렌드의 주기 분석
고순영, 박영선, 박명자
복식문화연구

This study analyzed the design elements and fashion images of women's knitwear in collections of Paris, Milan, London and New York between 2003 and 2008, and examined knitwear trends in an effort to verify whether knitwear trends are repeated in certain cycles, whether they show complicated patterns in cycles and yet occur in quasi cycles, or whether they occur non-periodically in complicated forms of chaotic cycles. Trend cycle analysis results are deemed to identify the time series attribute o

13
Article|2 citations·2008
Hard Disk Drive for HD Quality Multimedia Home Appliance
Jongmin Gim, Jaehyeok Chang, Hyungwon Jung, Youjip Won, Junseok Shim, Youngseon Park

In this work, we develop a novel audio and video (A/V) disk which is not only stronger for fragmentation but also getting higher bandwidth for multimedia home appliances. For our work, multimedia workload characteristics and disk overheads in multimedia home appliance are analyzed and then the concept of extent is redefined. If track size is only multiple size of extents, every I/O operation do not have track switch overhead. We suggest three ways of implementing our model in a real disk drive a

Computer Networks and CommunicationsComputer Science
14
Article|1 citations·2021
Cluster Analysis of Inhalant Allergens in South Korea: A Computational Model of Allergic Sensitization
김동규, 박영선, 차경준, 장대일, 류승호, 김경래, 김상헌, 윤호주, 조석현
https://doi.org/10.21053/ceo.2019.01921

Objectives. Sensitization to specific inhalant allergens is a major risk factor for the development of atopic diseases, which impose a major socioeconomic burden and significantly diminish quality of life. However, patterns of inhalant allergic sensitization have yet to be precisely described. Therefore, to enhance the understanding of aeroallergens, we performed a cluster analysis of inhalant allergic sensitization using a computational model. Methods. Skin prick data were collected from 7,504

15
Article|1 citations·2012
Fetal Heart Rate Regresses toward the Mean in the Third Trimester
박영선, 호정규, 박문일
Journal of Korean Medical Science

The purpose of this study was to investigate the feasibility of different fetal heart rate (FHR)ranges in the nonstress test (NST) and to better understand the meaning of mild bradycardia and/or tachycardia without non-reassuring patterns. We employed the heredity to show that mild bradycardia (100-119 beats per minute, bpm) and mild tachycardia (161-180 bpm) regressed to the normal FHR range (120-160 bpm). We used linear regression to analyze FHR data from FHR tracings recorded 10 min before (N

Research Areas

Computer Networks and CommunicationsImmunologyPharmacologyHematologyEpidemiology

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