손범석 교수
Beomseok Son
성균관대학교 의학과 · 의학
연구실 소개
손범석 교수의 연구실은 의료 영상 기반 정밀의료를 핵심 목표로 하며, 특히 초음파, MRI, CT 등 다양한 영상 데이터를 활용한 레이디오믹스 기반 질병 진단 및 예후 예측 모델을 개발하고 있습니다. 신장, 간질환, 뇌신경종양, 구강암 등 다양한 종양 및 신경질환에서 영상 특징을 정량화하고, 분자유전자 정보와 연계한 다변량 예측 모델을 구축함으로써 개인화된 의료에 기여하고자 합니다. 특히 소프트웨어 기반 영상 보조 진단 도구의 임상적 유용성과 정확도 향상에 대한 연구도 활발히 진행 중입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Obtaining ARFI measurements of the kidney is feasible in young children with median SWVs of 1.75 m/sec in normal kidneys. Median SWVs increased in high-grade hydronephrotic kidneys but were not different between hydronephrotic kidneys with and without UPJO.
OBJECTIVES: To investigate whether a radiomic MRI feature-based prediction model can differentiate oropharyngeal squamous cell carcinoma (SCC) according to the human papillomavirus (HPV) status. STUDY DESIGN: Retrospective cohort study. METHODS: Pretreatment MRI data from 62 consecutive patients with oropharyngeal SCC were retrospectively reviewed, and chronologically allocated to training (n = 43) and test sets (n = 19). Enhancing tumors were semi-automatically segmented on each slice of the po
PURPOSE: In glioma, molecular alterations are closely associated with disease prognosis. This study aimed to develop a radiomics-based multiple gene prediction model incorporating mutual information of each genetic alteration in glioblastoma and grade 4 astrocytoma, IDH-mutant. METHODS: From December 2014 through January 2020, we enrolled 418 patients with pathologically confirmed glioblastoma (based on the 2016 WHO classification). All selected patients had preoperative MRI and isocitrate dehyd
Software-aided reading showed significant incremental value in the sensitivity of clinicians in the detection of aneurysms on MRA without a significant increase in false-positive findings, especially for the neurosurgeon and neurologist. Software-aided reading showed equivocal value for the radiologist.
Background Cervical node metastasis is one of the most significant prognostic factors in patients with oropharyngeal squamous cell carcinoma (SCC). There is little information regarding the comparison of histopathologic analysis following neck dissection with imaging results in oropharyngeal SCC. Purpose To investigate the clinical utility of PET-CT compared with computed tomography (CT) or magnetic resonance imaging (MRI) for detecting nodal metastasis in oropharyngeal SCC patients with palpabl
BACKGROUND: The clinical presentation of juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures alone (GTCA) is similar, and MRI scans are often perceptually normal in both conditions making them challenging to differentiate. PURPOSE: To develop and validate an MRI-based radiomics model to accurately diagnose JME and GTCA, as well as to classify prognostic groups. STUDY TYPE: Retrospective. POPULATION: 164 patients (127 with JME and 37 with GTCA) patients (age 24.0
By comparing the prevalence of emotional and behaviour health problems among institutionalized juvenile offenders with that amongst a non‐offending sample of adolescents, this study indicates common characteristics of the perceived emotional and behavioural problems, and describes risk factors pertinent to persistent juvenile offending. Familial backgrounds, behavioural and emotional measures were collected through self‐report surveys. Results showed that young people in secure units claimed sig
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