김빛내리 교수
Bit-nae Kim
서울대학교 생명과학부 · 생화학·유전·분자생물학
연구실 소개
김빛내리 교수의 연구실은 전사 후 조절 메커니즘, 특히 mRNA의 번역 및 분해 조절, 소형 RNA의 생합성 및 기능, 그리고 바이러스 유전체의 전사체 구조를 중심으로 연구를 진행하고 있습니다. 특히 노폐물 제거 기전인 NMD(노ãn형 mRNA 분해)와 mRNA 꼬리의 구조적 변화가 번역 조절에 미치는 영향, 그리고 SARS-CoV-2의 복잡한 전사체 구조 규명 등에서 핵심적 성과를 내고 있습니다. 또한 고정밀 소형RNA 시퀀싱 기술을 개발하여 miRNA 및 isomiR의 정확한 정량을 가능하게 하여, 유전자 조절 네트워크의 이해를 심화하고 있습니다.
mRNA 조절소형RNA전사체 분석NMD고정밀 시퀀싱
연구 현황
논문 수
213
총 인용 수
38,731
최근 5년 논문
35
주요 분야
생화학·유전·분자생물학
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
5개년 연도별 논문 게재 수
35총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
973총합
20222023202420252026
주요 논문
151
논문|인용수 5,074·2003
The nuclear RNase III Drosha initiates microRNA processingYoontae Lee, Chiyoung Ahn, Jinju Han, Hyounjeong Choi, Jaekwang Kim, Jeongbin Yim, Junho Lee, Patrick Provost, Olof Rådmark, Sunyoung Kim, V. Narry Kim
SJR Q1Nature
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
논문|인용수 4,302·2004
MicroRNA genes are transcribed by RNA polymerase IIYoontae Lee, Minju Kim, Jinju Han, Kyu-Hyun Yeom, Sanghyuk Lee, Sung Hee Baek, V. Narry Kim
SJR Q1The EMBO JournalOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
3
리뷰|인용수 3,147·2009
Biogenesis of small RNAs in animalsV. Narry Kim, Jinju Han, Mikiko C. Siomi
SJR Q1Nature Reviews Molecular Cell Biology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
리뷰|인용수 2,507·2005
MicroRNA biogenesis: coordinated cropping and dicingV. Narry Kim
SJR Q1Nature Reviews Molecular Cell Biology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
5
논문|인용수 2,363·2020
The Architecture of SARS-CoV-2 TranscriptomeDong-Wan Kim, Joo-Yeon Lee, Jeong‐Sun Yang, Jun Won Kim, V. Narry Kim, Hyeshik Chang
SJR Q1CellOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
논문|인용수 1,534·2006
Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 ComplexJinju Han, Yoontae Lee, Kyu‐Hyeon Yeom, Jin‐Wu Nam, Inha Heo, Je‐Keun Rhee, Sun Young Sohn, Yunje Cho, Byoung-Tak Zhang, V. Narry Kim
SJR Q1CellOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
7
리뷰|인용수 889·2006
Genomics of microRNAV. Narry Kim, Jin‐Wu Nam
SJR Q1Trends in Genetics
Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
논문|인용수 774·2009
TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA UridylationInha Heo, Chirlmin Joo, Young Kook Kim, Minju Ha, Mi-Jeong Yoon, Jun Cho, Kyu‐Hyeon Yeom, Jinju Han, V. Narry Kim
SJR Q1CellOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
9
논문|인용수 606·2008
miR-29 miRNAs activate p53 by targeting p85α and CDC42Seong Yeon Park, Jung Hyun Lee, Minju Ha, Jin‐Wu Nam, V. Narry Kim
SJR Q1Nature Structural & Molecular Biology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
10
논문|인용수 514·2011
Dicer recognizes the 5′ end of RNA for efficient and accurate processingJong‐Eun Park, Inha Heo, Yuan Tian, Dhirendra K. Simanshu, Hyeshik Chang, David Jee, Dinshaw J. Patel, V. Narry Kim
SJR Q1Nature
Cancer ResearchBiochemistry, Genetics and Molecular Biology
11
논문|인용수 480·2014
TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End ModificationsHyeshik Chang, Jaechul Lim, Minju Ha, V. Narry Kim
SJR Q1Molecular CellOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
논문|인용수 475·2009
Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancerYoung Kook Kim, Jieun Yu, Tae Su Han, Seong-Yeon Park, Bumjin Namkoong, Dong Hyuk Kim, Keun Hur, Moon‐Won Yoo, Hyuk-Joon Lee, Han‐Kwang Yang, V. Narry Kim
SJR Q1Nucleic Acids ResearchOA
microRNAs (miRNAs) play integral roles in diverse processes including tumorigenesis. miRNA gene loci are often found in close conjunction, and such clustered miRNA genes are transcribed from a common promoter to generate polycistronic primary transcript. The primary transcript (pri-miRNA) is then processed by two RNase III proteins to release the mature miRNAs. Although it has been speculated that the miRNAs in the same cluster may play related biological functions, this has not been experimenta
Cancer ResearchBiochemistry, Genetics and Molecular Biology
13
논문|인용수 445·2009
Posttranscriptional Crossregulation between Drosha and DGCR8Jinju Han, Jakob Skou Pedersen, S. Chul Kwon, Cassandra D. Belair, Young Kook Kim, Kyu‐Hyeon Yeom, Woo‐Young Yang, David Haussler, Robert Blelloch, V. Narry Kim
SJR Q1CellOA
GeneticsBiochemistry, Genetics and Molecular Biology
14
리뷰|인용수 340·2024
Small and long non-coding RNAs: Past, present, and futureLing‐Ling Chen, V. Narry Kim
SJR Q1Cell
Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
논문|인용수 318·2009
Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3KSeogang Hyun, Jung‐Hyun Lee, Hua Jin, Jin‐Wu Nam, Bumjin Namkoong, Gina Lee, Jongkyeong Chung, V. Narry Kim
SJR Q1CellOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
대표 연구 분야
Molecular BiologyCancer ResearchGeneticsPlant ScienceRadiology, Nuclear Medicine and ImagingCellular and Molecular Neuroscience
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