서보경 교수
Bo-kyung Seo
고려대학교 영상의학과 · 의학
연구실 소개
서보경 교수의 연구실은 유방암의 정밀 진단과 생체정보 분석을 목표로, 초음파, CT, MRI 등 다양한 영상유도 진단 기술을 기반으로 한 비침습적 조직 경도 측정과 혈류 역학 분석을 연구하고 있습니다. 특히, 저선량 CT를 활용한 혈류퍼지모델링과 텍스처 분석을 통해 종양의 생물학적 특성과 예후 지표를 연관 짓는 데 초점을 맞추고 있으며, 머신러닝 기반 영상 해석 기술의 임상적 유효성도 함께 검증하고 있습니다. 이는 개인 맞춤형 치료 전략 수립에 기여할 수 있는 정밀의료 기반 연구입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15At CT, SMM appears as a result of malignant neoplasms, inflammation, or vascular disorders.
Abstract Background Shear wave elastography (SWE) is an ultrasound technique for the noninvasive quantification of tissue stiffness. The hypoxic tumor microenvironment promotes tumor stiffness and is associated with poor prognosis in cancer. We aimed to investigate the correlation between tumor hypoxia and histologic biomarkers and tumor stiffness measured by SWE in breast cancer. Methods From June 2016 to January 2018, 82 women with invasive breast cancer who underwent SWE before treatment were
BACKGROUND: We aimed to investigate the efficacy of computer-aided detection (CAD) for MRI in the assessment of tumor extent, lymph node status, and multifocality in invasive breast cancers in comparison with other breast imaging modalities. METHODS: Two radiologists measured the maximum tumor size, as well as, analyzed lymph node status and multifocality in 86 patients with invasive breast cancers using mammography, ultrasound, CT, MRI with and without CAD, and 18-fludeoxyglucose positron emiss
Real-time compound and pulse-inversion harmonic imaging procedures are superior to conventional sonography in terms of both lesion conspicuity and the further characterization of breast nodules. Real-time compound imaging is the best technique for evaluation of the margin and internal echotexture of nodules, while pulse-inversion harmonic imaging is very effective for the evaluation of the posterior echo patterns.
This prospective study enrolled 147 women with invasive breast cancer who underwent low-dose breast CT (80 kVp, 25 mAs, 1.01-1.38 mSv) before treatment. From each tumor, we extracted eight perfusion parameters using the maximum slope algorithm and 36 texture parameters using the filtered histogram technique. Relationships between CT parameters and histological factors were analyzed using five machine learning algorithms. Performance was compared using the area under the receiver-operating charac
OBJECTIVES: The aim of this study was to investigate the feasibility of using low-dose perfusion computed tomography (CT) in breast cancers for quantification of tumor vascularity and to correlate perfusion indexes with prognostic biomarkers. MATERIALS AND METHODS: This preliminary study was approved by our institutional review board. Signed informed consent was obtained from all 70 enrolled patients with invasive breast cancers. Low-dose perfusion CT was performed with the patient in the prone
BACKGROUND: There are few prospective studies on the correlations between MRI features and whole RNA-sequencing data in breast cancer according to molecular subtypes. The purpose of our study was to explore the association between genetic profiles and MRI phenotypes of breast cancer and to identify imaging markers that influences the prognosis and treatment according to subtypes. METHODS: From June 2017 to August 2018, MRIs of 95 women with invasive breast cancer were prospectively analyzed, usi
『新撰姓氏錄』은 平安京의 左京, 右京 및 畿內를 本貫으로 한 1182씨의 출자를 三體로 분류하여 계보관계를 정리한 계보총람이다. 桓武天皇이 延曆 18(799)년에 각 씨족에게 본계장의 제출의 명을 내리면서 편찬 작업이 시작되었고, 그로부터 16년 뒤인 嵯峨天皇 弘仁 6(815)년 7월에 桓武의 아들인 萬多親王이 주축이 되어 완성을 보았다. 또한 편찬에 참여한 藤原緖嗣와 藤原園人 등도 桓武天皇의 측근으로 활약한 인물들이다. 그러한 만큼 『신찬성씨록』은 桓武朝의 관념이 투영된 산물이다. 桓武天皇은 이른바 ‘天智系皇統’을 실질적으로 부활시킨 인물로, 奈良시대를 통해 계속적으로 이행된 天武國忌日의 廢務를 행하지 않았고, 昭穆制의 도입을 통해 光仁天皇을 태조나 고조에 비정하며 交野의 柏原에서 제사지냈으며, 천무계 황통의 도읍지였던 奈良의 平城京을 떠나 山城 지역으로 도읍 자체를 옮겼다. 이러한 일련의 움직임은 환무천황이 奈良시대를 통해 뿌리내린 ‘天武重視’ 의식을 타파하고 새로운 시대를 구축
In this treatise, by examining the article on the summons of Dalsol Illa, appearing in Bitatsu Dynasty in 『Nihonshogi』, could be confirmed the following facts. The point one is about the fact that the moves of leading clans inside Yamato Court, appearing related with the summons of Dalsol Illa, is directly related to the issue-what we call-of arising and abolishing of bureaucrats from Wae working for Baekje. Illa, whose clan was living in Webuk, is seen as having been dispatched by Otomo to whom
대표 연구 분야
서보경 교수의 연구를 Nubint에서 더 깊이 살펴보세요
이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.