이보은 교수
Boeun Lee
이화여자대학교 의학과 · 의학
연구실 소개
이보은 교수의 연구실은 의료 영상 기반의 질병 진단 및 예후 예측을 핵심으로 삼고 있으며, 뇌종양 및 구강경부암 환자의 생존 예측에 활용 가능한 영상 생체지표 개발에 주력하고 있습니다. 특히 뇌와 두부경부 영상에서 관찰되는 타임스스근 두께(TMT)가 근육량 감소와 연관되어 임상적 예후를 예측하는 데 기여할 수 있음을 규명하고 있습니다. 또한, 로봇 운동 계획 및 의료 영상에서의 혈관 투과성 분석을 통해 정밀의료와 진단 정밀도 향상에 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15An approach to collision-free motion planning of two moving robots in a common workspace is presented. Each robot is represented by a sphere containing the wrist and the manipulator hand. The results from a strictly straight line trajectory planning method are utilized for planning a path avoiding potential collisions. Due to the distinct nature of the potential collisions between the two moving robots, a new classification of path requirement situations is presented and utilized for planning a
OBJECTIVES: β-Lactam antibiotics are commonly used in outpatient parenteral antimicrobial therapy (OPAT), but data regarding outcomes of long-term therapy are limited. The purpose of this study was to compare treatment success, readmission and antibiotic switch rates in patients treated with β-lactam antibiotics as OPAT. METHODS: We carried out a retrospective review of all patients, discharged from Tufts Medical Center with cefazolin, ceftriaxone, ertapenem or oxacillin, between January 2009 an
Temporalis muscle thickness (TMT) on brain magnetic resonance imaging (MRI) is correlated with sarcopenia and can be a predictive marker for survival in patients with brain tumors, but the association of TMT on head and neck computed tomography (CT) with survival in head and neck squamous cell carcinoma (HNSCC) remains unclear. We investigated whether TMT on CT could predict progression-free survival (PFS) in patients with HNSCC. A total of 106 patients with newly diagnosed HNSCC were included i
Radiologic ENE on CT or MRI did not predict poor PFS in patients with HPV-related OPSCC, although there was a trend towards worse PFS. Further studies are warranted to determine whether radiologic ENE is a useful imaging biomarker to risk-stratify patients with HPV-related OPSCC.
Estimation of vascular permeability with DSC-MR imaging further characterizes hypervascular primary central nervous system lymphoma and improves diagnostic performance in glioblastoma differentiation.
This paper addresses an overview of time-varying obstacle avoidance problems for robotic manipulators. We propose four different approaches to solving these problems. They are the Heuristic Off-line (HOF) approach, the Heuristic On-line (HON) approach, the Analytic Off-line (AOF) approach, and the Analytic On-line (AON) approach. The AOF approach is particularly pursued and derived in this paper. Some fundamental difficulties are then discussed in the AOF approach. It is shown that the analytic
Autoimmune and autoinflammatory inner ear diseases (AIED/AID) are characterized by the symptom of sensorineural hearing loss (SNHL). To date, standardized diagnostic tools for AIED/AID are lacking, and clinically differentiating AIED/AID from chronic otitis media (COM) with SNHL is challenging. This retrospective study aimed to construct a magnetic resonance imaging (MRI)-based decision tree using classification and regression tree (CART) analysis to distinguish AIED/AID from COM. In total, 67 p
Dokdonella koreensis is a non-spore-forming, aerobic, Gram-negative bacillus that was initially isolated from soil. The pathogenicity of this organism in humans remains unclear. The authors report a case of successfully treated D koreensis bacteremia in a patient with a hematological malignancy who presented with a fever and palmar-plantar erythrodysesthesia.
PURPOSE: The aim of this study was to assess the diagnostic role of fine-needle aspiration cytology (FNAC) and analyze factors associated with false-negative FNAC results in patients with parathyroid incidentaloma who were referred for ultrasonography (US)-guided fine-needle aspiration (FNA) of thyroid nodules. METHODS: In this study, 121 patients with suspected parathyroid lesions were enrolled. The patients underwent US-guided FNAC with measurements of washout parathyroid hormone (PTH) between
Granulomatosis with polyangiitis (GPA) can involve the skull base or the Eustachian tubes. GPA is diagnosed on the basis of clinical manifestations and serological tests, although it is challenging to discriminate GPA from infectious processes driving skull base osteomyelitis (SBO) and malignant processes such as nasopharyngeal carcinoma (NPC). Moreover, current serological tests have a low sensitivity and cannot distinguish GPA from these other conditions. We hypothesized that certain MRI chara
PURPOSE: This study aimed to develop the ultrasonography (US) criteria for risk stratification of the Korean Thyroid Imaging Reporting and Data System (K-TIRADS) 4 nodules, and to evaluate the diagnostic yield of a modified biopsy criterion in a multicenter cohort. METHODS: In total, 1,542 K-TIRADS 4 nodules (≥1 cm) were included in the study. US criteria for the subcategorization of K-TIRADS 4 nodules were developed based on high-risk US features. The diagnostic yields and false referral rates
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