서병성 교수
Byeongseong Seo
성균관대학교 의학과 · 의학
연구실 소개
서병성 교수의 연구실은 만성질환의 조기 발병 위험을 예측하고 예방 전략을 모색하는 데 초점을 맞추고 있습니다. 특히 간기능 지표인 감마글루타밀트라누스퍼아제(GGT), 비만 및 체중 변화, 비알코올성간지방질간염(NAFLD) 등 대사성 질환과 만성신질환 간의 연관성을 종단적 연구를 통해 규명하고 있습니다. 또한 직업적 스트레스, 수면 질, 신체활동 수준 등 생활습관과 환경 요인이 건강에 미치는 영향을 다각도로 분석하고 있습니다. 특히 산업현장과 직장인을 대상으로 한 대규모 건강 코hort 연구를 기반으로 한 실증적 연구가 특징입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15None.
BACKGROUND: Little research has been done to examine whether gamma-glutamyltransferase (GGT) is prospectively associated with the development of chronic kidney disease (CKD). We performed a prospective study to examine the association between GGT and the risk for the development of CKD. METHODS: The study cohort included a total of 10 337 healthy males with normal baseline kidney functions and no proteinuria. Participants were workers in a semiconductor manufacturing company and its 13 affiliate
Several recent prospective studies have reported that obesity is associated with an increased risk for chronic kidney disease (CKD), but it is unknown whether weight gain increases the risk for CKD if one remains within the "normal" category of body mass index (BMI). We prospectively followed a cohort of 8792 healthy men who had no known risk factors for CKD and participated in a comprehensive health evaluation program at a large worksite. During 35,927 person-years of follow-up, 427 new inciden
Objectives: This study was performed to assess the level of job and psychosocial stresses in Korean firefighters, and to evaluate the determinants of psychosocial stress. Methods: The study subjects comprised 1,712 male firefighters working in Seoul, Busan, and Kyungnam in 2006. We collected information about demographic and job-related characteristics, healthrelated behaviors, Korean Occupational Stress Scale (KOSS), and psychosocial Well-being Index (PWI) through self-administered questionnair
Nonalcoholic fatty liver disease (NAFLD) and gallstone disease (GD) are often found to coexist but the sequential relationship of NAFLD and GD to each other remains controversial. We prospectively evaluated the bidirectional relationship of NAFLD with GD. A cohort study was performed on Korean adults who underwent a health checkup and were followed annually or biennially for a mean of 6.0 years. Fatty liver and gallstones were diagnosed by ultrasound. NAFLD was defined as hepatic steatosis on ul
Shift work directly causes circadian disruption and reduces sleep quality. Physical activity is also associated with sleep quality. However, no study has reported the relationship between a specific level of physical activity and sleep quality. This study aimed to investigate the relationship between sleep quality and the amount of physical activity by stratifying subjects into gender and shift-work subgroups. Among those who participated in the Kangbuk Samsung Health Study in 2016-2017, data fr
Environmental exposure to cadmium in abandoned mine residents was associated with diabetes in male. Closed monitoring and periodic evaluation of the health effects of chronic environmental exposure on abandoned mines residents will be needed.
Shift work is associated with vitamin D level, sleep quality, and depressive symptoms. Vitamin D and sleep quality are also associated with depressive symptoms. The purpose of this study was to compare vitamin D level, sleep quality, and depressive symptoms between shift workers and daytime workers and analyze the mediating effect of vitamin D and sleep quality between shift work and depressive symptoms. Among those who participated in the Kangbuk Samsung Health Study in 2012 and 2014, 82,078 ca
Our results provide an objective explanation for considerable interobserver variability in the diagnosis of high-grade pulmonary NE carcinomas. Further studies would need to define more stringent and objective definitions of cytologic and architectural characteristics to reliably distinguish between SCLC and LCNEC.
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