박채정 교수
Chae Jung Park
연세대학교 영상의학과 · 의학
연구실 소개
박채정 교수의 연구실은 뇌영상 영상의학과 신경과학을 융합한 정밀의료 연구를 주도하고 있습니다. 주로 파킨슨병 및 치매와 같은 신경퇴행성 질환에서 뇌의 간질류계(글리암파트) 기능 평가와 함께, 다중모달리즘 영상(특히 MRI 기반 레이디오믹스)을 활용한 조기 진단 및 예후 예측 모델 개발에 집중하고 있습니다. 특히, 비침습적 영상 기반 지표를 통해 뇌의 뇌간질류 기능 이상을 정량화하고, 임상 정보와 융합한 인공지능 기반 예측 알고리즘을 개발함으로써 신경질환의 조기 발견과 개인 맞춤 치료 전략 수립에 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15BACKGROUND AND PURPOSE: The choroid plexus (CP) clears harmful metabolites from the central nervous system as part of the glymphatic system. We investigated the association of CP volume (CPV) with baseline and longitudinal cognitive decline in patients with Parkinson disease (PD). METHODS: We retrospectively reviewed the medical records of 240 patients with newly diagnosed PD who had undergone detailed neuropsychological tests and high-resolution T1-weighted structural magnetic resonance imaging
MR imaging features integrated with machine learning classifiers may predict a subset of <i>IDH</i> wild-type lower-grade gliomas that carry molecular features of glioblastoma.
The overall scientific and reporting quality of radiomics studies on brain metastases published during the study period was insufficient. Radiomics studies should adhere to the RQS, TRIPOD, and IBSI guidelines to facilitate the translation of radiomics into the clinical field.
Objectives Diffusion tensor image analysis along the perivascular space (DTI-ALPS) is a recently introduced method for the assessment of the glymphatic system without the need for contrast injection. The purpose of our study was to assess the glymphatic system in cognitively normal older adults with or without subjective cognitive decline (SCD) using DTI-ALPS, and correlating with amyloid PET. Design and participants To evaluate the glymphatic system in cognitively normal older adults using DTI-
PURPOSE: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients.\n\nMETHODS: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-gui
Cognitive impairment in Parkinson's disease (PD) severely affects patients' prognosis, and early detection of patients at high risk of dementia conversion is important for establishing treatment strategies. We aimed to investigate whether multiparametric MRI radiomics from basal ganglia can improve the prediction of dementia development in PD when integrated with clinical profiles. In this retrospective study, 262 patients with newly diagnosed PD (June 2008-July 2017, follow-up >5 years) were in
OBJECTIVES: This study investigated whether radiomic features can improve the prediction accuracy for tumor recurrence over clinicopathological features and if these features can be used to identify high-risk patients requiring adjuvant radiotherapy (ART) in WHO grade 2 meningiomas. METHODS: Preoperative magnetic resonance imaging (MRI) of 155 grade 2 meningioma patients with a median follow-up of 63.8 months were included and allocated to training (n = 92) and test sets (n = 63). After radiomic
The purpose of this study was to determine the diagnostic utility of low-dose CT with knowledge-based iterative model reconstruction (IMR) for the evaluation of parotid gland tumors. Materials and Methods: This prospective study included 42 consecutive patients who had undergone low-dose contrastenhanced CT for the evaluation of suspected parotid gland tumors. Prior or subsequent non-low-dose CT scans within 12 months were available in 10 of the participants. Background noise (BN), signal-to-noi
When US findings of thyroid nodules are assessed according to the 2015 ATA guidelines, nondiagnostic thyroid nodules with very-low- or low-suspicion US patterns can be followed up with US. Nondiagnostic nodules with intermediate or highly suspicious US patterns should be evaluated with repeat US-guided fine-needle aspiration biopsy.
Purpose: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. Methods: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided
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