이창훈 교수

Gastric cancers have recently been classified into several types on the basis of molecular characterization, and the new taxonomy has shown to have clinical relevance. However, the technology required for thorough molecular classification is complicated and expensive, currently preventing widespread use. We aimed to reproduce the results of molecular classification using only simple techniques, that is, immunohistochemical analysis and in situ hybridization. We classified a cohort of 349 success

Despite wide acceptance of the chronic gastritis-intestinal metaplasia-dysplasia-carcinoma sequence, especially for intestinal-type gastric adenocarcinoma, the precise nature of the subtle precursor lesions of gastric cancer remains to be delineated. For example, pit dysplasia with surface foveolar maturation is not well defined, nor is its prevalence and biological characteristics well characterized. We have evaluated the surrounding gastric mucosa of 414 gastric cancers for the presence of gas

The purpose of this study is to present a treatment algorithm and a method of flexor pollicis longus tendon relocation for Wassel type IV thumb duplication with zigzag deformity. Forty-two thumbs in 42 patients were included in this study and the mean follow-up was 4 years. In addition to excision of the extra digit, tendon relocation and metacarpal and/or proximal phalangeal osteotomy were carried out, based on the degree of angulation at the metacarpophalangeal and interphalangeal joints. Tend

Stratified charge compression ignition (SCCI) combustion, which is developed to extend the homogeneous charge compression ignition operating range, has a good potential to improve fuel economy and reduce emissions. In this study, SCCI combustion and emissions characteristics were investigated in a single-cylinder gasoline engine with a direct-injection system. From the experimental results, we elucidated the effects of air−fuel ratio, intake temperature, and injection timing including early and

본 논문은 한국 사회에서 지속적으로 논쟁되어 온 방송심의의 공정성 규제 현황과 적용의 문제점을 분석하고, 방송정책이념이 다른 정부 간 공정성 규제 실행에 차이가 있는지 살펴보았다. 2003년부터 2010년까지 방송심의결정 분석결과, 2008년부터 공정성 규제 증가 추세가 나타났고 규제의 타당성과 적용의 명확성에 대한 논쟁이 증가한 것으로 나타났다. 제재 건수가 가장 많은 객관성은 공정성 개념과 혼용되어 중복위반으로 제재되는 경우가 많았고 그 적용에 있어서도 추상성과 모호성으로 인해 적용의 명확성이 떨어지는 경향을 보였다. 가장 논란이 큰 균형성은 주로 양적 균형성을 요구하는 것으로 나타나 정부를 비판하는 텔레비전 프로그램조차 양적 균형을 요구하는 경향을 보여 정부에 대한 방송의 비판과 감시라는 본질적 기능을 위축시킬 가능성이 있는 것으로 판단된다.

In this paper, adaptive algorithms for updating the coefficients of an equalizer and a 2-state Viterbi detector for a partial response maximum likelihood (PRML) detector in a digital versatile disc record (DVDR) system are proposed and implemented with field programmable gate array (FPGA). The conventional partial response (PR) equalization method, derived under the conventional minimum mean square error (MMSE) criterion, exhibits performance degradation due to high-frequency noise enhancement e

Lymphangioma is an abnormal collection of lymphatics that are developmentally isolated from the normal lymphatic system. Lymphangioma rarely presents as a solitary pulmonary lesion. We report a rare case of intrapulmonary cystic lymphangioma involving the upper lobe of the right lung, which presented with dyspnea in a 2-month-old infant. High-resolution computed tomography (HRCT) of the chest demonstrated a well-circumscribed, multiseptate, cystic lesion in the upper lobe of the right lung, mimi

Peripheral nerve injuries (PNIs) in the upper extremities is an important medical problem, causing significant morbidity at a relatively young age. The epidemiology of PNI in South Korea has not been comprehensively evaluated. The purpose of our study was to examine the incidence of upper extremity PNI in South Korea based on an analysis of nationwide data and to investigate the association between PNI and patients' demographic characteristics. Patient claims data from the Health Insurance Revie

Herein, the surfactant effects on the thermosensitive swelling behaviors of nanometer-sized particle gels are investigated.

미디어환경 변화와 함께 새로운 미디어 이용행태로 나타난 다중미디어 이용의 이용특성과 미디어 효과를 알아보았다. 공급자 중심 시각이 아닌 이용자 중심의 시각에서 접근하기 위해 포괄적으로 미디어를 적용하고 이용유형을 결합해 30개의 이용행태 리스트를 도출하고 이를 이용해 7개의 레퍼토리로 분류했다. 7개 레퍼토리는 다중미디어 이용, 친교목적 뉴미디어 다중이용, 유선방송-라디오, 오락/친교형 유료방송-모바일-SNS, 오락형 인터넷-전화, 정보형 모바일-SNS-인터넷, 저 미디어 이용 레퍼토리였다. 분석결과는 두 개의 다중미디어 이용 레퍼토리가 도출돼 젊은 세대에서는 다중미디어 이용이 대중화되고 동시에 분화되고 있는 것으로 나타났고 선행연구에서 가장 비중이 컷 던 지상파TV 중심 레퍼토리가 나타나지 않고 모바일 미디어가 가장 중심적인 미디어로 나타났다. 미디어 효과 검증에서는 다중 미디어 이용수준이 높은 이용자들의 신뢰, 호혜성, 시민적 관여와 같은 사회적 효과는 물론 만족감, 즐거움, 애

Differences in biomechanical responses between groups were confirmed. Group A was less flexible and slower at energy relaxation under axial loading. A larger proportion of the external load was taken by the posterolateral part of the degenerative discs. These results were consistent with clinical experiences: 1) most hernias are observed more often at the posterolateral side than other sides, and 2) the degeneration attributable to age reduces the function of absorbing and distribution of extern