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이창영 교수

Chang Young Lee

연세대학교 흉부외과 · 의학

연구실 소개

이창영 교수의 연구실은 주로 폐암, 흉선암, 간세포암 등 호흡기 및 간질환과 관련된 악성 종양의 수술적 치료 및 예후 요인을 중심으로 연구를 진행하고 있습니다. 특히 비소세포성 폐암, 흉선암, 간세포암의 폐 전이에 대한 수술적 치료 결과와 예후 예측 요인을 분석하며, 생체 내 단백질 발현(예: MMP-9)과 같은 분자 생물학적 지표의 임상적 의미를 규명하고자 합니다. 또한 흉부외과 수술 후 통증 관리 및 환자 중심의 치료 전략 개선을 위한 임상 연구도 병행하고 있습니다.

폐암흉선암간세포암 전이예후 예측수술 치료

연구 현황

논문 수
197
총 인용 수
3,780
최근 5년 논문
36
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
36총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
231총합
20222023202420252026

주요 논문

15
1
논문|인용수 61·2009
Early Masaoka stage and complete resection is important for prognosis of thymic carcinoma: a 20-year experience at a single institution☆
Chang Young Lee, Mi Kyung Bae, In Kyu Park, Dae Joon Kim, Jin Gu Lee, Kyung Young Chung
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

OBJECTIVE: Prognosis of primary thymic carcinomas is poor due to advanced stage progression at diagnosis and highly malignant behavior. We retrospectively evaluated patients with thymic carcinoma to determine the prognostic factors. METHODS: Sixty patients diagnosed and treated for thymic carcinoma from 1986 to 2005 were reviewed retrospectively. Influences of demographic characteristics, Masaoka stage, histologic grade, completeness of resection and adjuvant treatment on survival were evaluated

NeurologyMedicine
2
논문|인용수 61·2010
Bilateral video-assisted thoracoscopic thymectomy has a surgical extent similar to that of transsternal extended thymectomy with more favorable early surgical outcomes for myasthenia gravis patients
Chang Young Lee, Dae Joon Kim, Jin Gu Lee, In Kyu Park, Mi Kyung Bae, Kyung Young Chung
SJR Q1Surgical EndoscopyOA
NeurologyMedicine
3
논문|인용수 43·2019
Dynamic changes in PD-L1 expression and CD8+ T cell infiltration in non-small cell lung cancer following chemoradiation therapy
Eun‐Ah Choe, Yoon Jin, Jae Hwan Kim, Kyoung‐Ho Pyo, Min Hee Hong, Sung Yong Park, Hyo Sup Shim, Inkyung Jung, Chang Young Lee, Byoung Chul Cho, Hye Ryun Kim
SJR Q1Lung CancerOA
OncologyMedicine
4
논문|인용수 43·2013
Efficacy of Polyglycolic Acid Sheet After Thoracoscopic Bullectomy for Spontaneous Pneumothorax
Seokkee Lee, Sung Yong Park, Mi Kyung Bae, Jin Gu Lee, Dae Joon Kim, Kyung Young Chung, Chang Young Lee
SJR Q1The Annals of Thoracic SurgeryOA
Pulmonary and Respiratory MedicineMedicine
5
논문|인용수 41·2012
The prognostic factors of resected non-small cell lung cancer with chest wall invasion
Chang Young Lee, Chun Sung Byun, Jin Gu Lee, Dae Joon Kim, Byoung Chul Cho, Kyung Soo Chung, In Kyu Park
SJR Q1World Journal of Surgical OncologyOA

BACKGROUND: We retrospectively reviewed the clinical features and surgical outcomes of patients with a surgically resected NSCLC invading chest wall in order to identify prognostic factors that impact long term survival. METHODS: Between January 1990 and December 2009, 107 patients who underwent surgical resection for chest wall invading NSCLC were reviewed. Tumors invading only the parietal pleura were defined as superficial invasions, and those involving the soft tissue or ribs were defined as

Pulmonary and Respiratory MedicineMedicine
6
논문|인용수 37·2010
Surgical resection for pulmonary metastasis from hepatocellular carcinoma: Analysis of prognosis in relation to primary control
Chang Young Lee, Mi Kyung Bae, In Kyu Park, Dae Joon Kim, Jin Gu Lee, Jin Sub Choi, Kwang‐Hyub Han, Kyung Soo Chung
SJR Q1Journal of Surgical OncologyOA

BACKGROUND: Advances in local treatments for hepatocellular carcinoma (HCC) have seen better prognosis. There were few studies on surgery for pulmonary metastasis from HCC controlled by local treatment. This study was conducted to analyze prognostic factors after surgery for pulmonary metastasis from HCC. METHODS: We reviewed 32 patients who underwent surgery for pulmonary metastasis from HCC and analyzed prognostic factors. RESULTS: HCC was controlled by surgery in 16 patients and by local trea

HepatologyMedicine
7
논문|인용수 25·2020
Stepwise flowchart for decision making on sublobar resection through the estimation of spread through air space in early stage lung cancer1
Jee Won Suh, Yong Hyu Jeong, Arthur Cho, Dae Joon Kim, Kyoung Young Chung, Hyo Sup Shim, Chang Young Lee
SJR Q1Lung CancerOA
Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 24·2015
Prognostic effect of matrix metalloproteinase-9 in patients with resected Non small cell lung cancer
Chang Young Lee, Hyo Sup Shim, Seokkee Lee, Jin Gu Lee, Dae Joon Kim, Kyung Young Chung
SJR Q2Journal of Cardiothoracic SurgeryOA

BACKGROUND: The role of tumor matrix metalloproteinase-9 (MMP-9) expression in non-small cell lung cancer (NSCLC) remains controversial. In this study, we investigated the prognostic value of tumor MMP-9 expression and other clinicopathologic factors in patients with completely resected NSCLC. METHODS: This retrospective study included patients who underwent complete resection of pathological stage I-IIIA NSCLC at Severance Hospital, Seoul, Korea, between 1998 and 2009. Tumor samples of 417 pati

Cancer ResearchBiochemistry, Genetics and Molecular Biology
9
논문|인용수 16·2022
Prognosis of resected invasive mucinous adenocarcinoma compared with the IASLC histologic grading system for invasive nonmucinous adenocarcinoma: Surgical database study in the TKIs era in Korea
Wongi Woo, Young Ho Yang, Yoon Jin, Duk Hwan Moon, Hyo Sup Shim, Arthur Cho, Bong Jun Kim, Ha Eun Kim, Byung Jo Park, Jin Gu Lee, Dae Joon Kim, Hyo Chae Paik
SJR Q2Thoracic CancerOA

BACKGROUND: The prognosis of invasive mucinous adenocarcinoma (IMA) remains controversial and should be clarified by comparison with the International Association for the Study of Lung Cancer (IASLC) histologic grading system for invasive nonmucinous adenocarcinoma (INMA). METHODS: This study included patients with IMA who underwent curative resection. Their clinicopathological outcomes were compared with those of patients with INMA. Propensity score matching was performed to compare the prognos

Pulmonary and Respiratory MedicineMedicine
10
논문|인용수 16·2018
A prospective randomized trial of continuous paravertebral infusion versus intravenous patient-controlled analgesia after thoracoscopic lobectomy for lung cancer
Chang Young Lee, Kyoung Shik Narm, Jin Gu Lee, Hyo Chae Paik, Kyung Young Chung, Ha Young Shin, Ha Young Yeom, Dae Joon Kim
SJR Q2Journal of Thoracic DiseaseOA

title: A prospective randomized trial of continuous paravertebral infusion versus intravenous patient-controlled analgesia after thoracoscopic lobectomy for lung cancer, doi: 10.21037/jtd.2018.05.161, category: Article

SurgeryMedicine
11
논문|인용수 14·2018
Novel Thoracoscopic Navigation System With Augmented Real-Time Image Guidance for Chest Wall Tumors
Chang Young Lee, Harley Chan, Hideki Ujiie, Kosuke Fujino, Tomonari Kinoshita, Jonathan C. Irish, Kazuhiro Yasufuku
SJR Q1The Annals of Thoracic SurgeryOA
RadiationPhysics and Astronomy
12
논문|인용수 12·2020
Photoacoustic imaging to localize indeterminate pulmonary nodules: A preclinical study
Chang Young Lee, Kosuke Fujino, Yamato Motooka, Alexander Gregor, Nicholas Bernards, Hideki Ujiie, Tomonari Kinoshita, Kyung Young Chung, Seung Hee Han, Kazuhiro Yasufuku
SJR Q1PLoS ONEOA

The results from this preclinical study suggests that PAI of injected ICG-agar may be beneficial for identifying deeply located tumors. These features may be valuable for IPNs.

Biomedical EngineeringEngineering
13
논문|인용수 10·2022
Proposal of a revised International Association for the Study of Lung Cancer grading system in pulmonary non-mucinous adenocarcinoma: The importance of the lepidic proportion
Byung Jo Park, Wongi Woo, Yoon Jin, Hyo Sup Shim, Young Ho Yang, Duk Hwan Moon, Bong Jun Kim, Ha Eun Kim, Dae Joon Kim, Hyo Chae Paik, Jin Gu Lee, Sungsoo Lee
SJR Q1Lung CancerOA
Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 10·2016
Three-Dimensional Ground Glass Opacity Ratio in CT Images Can Predict Tumor Invasiveness of Stage IA Lung Cancer
이창영, 유우식, 홍새롬, 이진구, 이재석, 정희석, 김대준, 정경영
http://ymj.kr/DOIx.php?id=10.3349/ymj.2016.57.5.1131

Purpose: We investigated the relationship between various parameters, including volumetric parameters, and tumor invasivenessaccording to the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/EuropeanRespiratory Society (ERS) classification. Materials and Methods: We retrospectively reviewed 99 patients with completely resected stage IA lung adenocarcinoma. The correlation between several parameters [one-dimensional ground glass opacity (1D GGO) ratio

15
논문|인용수 8·2011
N-Terminal Pro-B-type Natriuretic Peptide Is Useful to Predict Cardiac Complications Following Lung Resection Surgery
Chang Young Lee, Mi Kyung Bae, Jin Gu Lee, Kwan-wook Kim, In Kyu Park, Kyung Soo Chung
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

BACKGROUND: Cardiovascular complications are major causes of morbidity and mortality following non-cardiac thoracic operations. Recent studies have demonstrated that elevation of N-Terminal Pro-B-type natriuretic peptide (NT-proBNP) levels can predict cardiac complications following non-cardiac major surgery as well as cardiac surgery. However, there is little information on the correlation between lung resection surgery and NT-proBNP levels. We evaluated the role of NT-proBNP as a potential mar

Cardiology and Cardiovascular MedicineMedicine

대표 연구 분야

Pulmonary and Respiratory MedicineNeurologySurgeryOncologyBiomedical EngineeringCancer Research

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