이창영 교수
Chang Young Lee
연세대학교 흉부외과 · 의학
연구실 소개
이창영 교수의 연구실은 주로 폐암, 흉선암, 간세포암 등 호흡기 및 간질환과 관련된 악성 종양의 수술적 치료 및 예후 요인을 중심으로 연구를 진행하고 있습니다. 특히 비소세포성 폐암, 흉선암, 간세포암의 폐 전이에 대한 수술적 치료 결과와 예후 예측 요인을 분석하며, 생체 내 단백질 발현(예: MMP-9)과 같은 분자 생물학적 지표의 임상적 의미를 규명하고자 합니다. 또한 흉부외과 수술 후 통증 관리 및 환자 중심의 치료 전략 개선을 위한 임상 연구도 병행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15OBJECTIVE: Prognosis of primary thymic carcinomas is poor due to advanced stage progression at diagnosis and highly malignant behavior. We retrospectively evaluated patients with thymic carcinoma to determine the prognostic factors. METHODS: Sixty patients diagnosed and treated for thymic carcinoma from 1986 to 2005 were reviewed retrospectively. Influences of demographic characteristics, Masaoka stage, histologic grade, completeness of resection and adjuvant treatment on survival were evaluated
BACKGROUND: We retrospectively reviewed the clinical features and surgical outcomes of patients with a surgically resected NSCLC invading chest wall in order to identify prognostic factors that impact long term survival. METHODS: Between January 1990 and December 2009, 107 patients who underwent surgical resection for chest wall invading NSCLC were reviewed. Tumors invading only the parietal pleura were defined as superficial invasions, and those involving the soft tissue or ribs were defined as
BACKGROUND: Advances in local treatments for hepatocellular carcinoma (HCC) have seen better prognosis. There were few studies on surgery for pulmonary metastasis from HCC controlled by local treatment. This study was conducted to analyze prognostic factors after surgery for pulmonary metastasis from HCC. METHODS: We reviewed 32 patients who underwent surgery for pulmonary metastasis from HCC and analyzed prognostic factors. RESULTS: HCC was controlled by surgery in 16 patients and by local trea
BACKGROUND: The role of tumor matrix metalloproteinase-9 (MMP-9) expression in non-small cell lung cancer (NSCLC) remains controversial. In this study, we investigated the prognostic value of tumor MMP-9 expression and other clinicopathologic factors in patients with completely resected NSCLC. METHODS: This retrospective study included patients who underwent complete resection of pathological stage I-IIIA NSCLC at Severance Hospital, Seoul, Korea, between 1998 and 2009. Tumor samples of 417 pati
BACKGROUND: The prognosis of invasive mucinous adenocarcinoma (IMA) remains controversial and should be clarified by comparison with the International Association for the Study of Lung Cancer (IASLC) histologic grading system for invasive nonmucinous adenocarcinoma (INMA). METHODS: This study included patients with IMA who underwent curative resection. Their clinicopathological outcomes were compared with those of patients with INMA. Propensity score matching was performed to compare the prognos
title: A prospective randomized trial of continuous paravertebral infusion versus intravenous patient-controlled analgesia after thoracoscopic lobectomy for lung cancer, doi: 10.21037/jtd.2018.05.161, category: Article
The results from this preclinical study suggests that PAI of injected ICG-agar may be beneficial for identifying deeply located tumors. These features may be valuable for IPNs.
Purpose: We investigated the relationship between various parameters, including volumetric parameters, and tumor invasivenessaccording to the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/EuropeanRespiratory Society (ERS) classification. Materials and Methods: We retrospectively reviewed 99 patients with completely resected stage IA lung adenocarcinoma. The correlation between several parameters [one-dimensional ground glass opacity (1D GGO) ratio
BACKGROUND: Cardiovascular complications are major causes of morbidity and mortality following non-cardiac thoracic operations. Recent studies have demonstrated that elevation of N-Terminal Pro-B-type natriuretic peptide (NT-proBNP) levels can predict cardiac complications following non-cardiac major surgery as well as cardiac surgery. However, there is little information on the correlation between lung resection surgery and NT-proBNP levels. We evaluated the role of NT-proBNP as a potential mar
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