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김창오 교수

Changwo Kim

연세대학교 내과 · 의학

연구실 소개

김창오 교수의 연구실은 노화와 관련된 만성질환, 특히 고령층에서 흔한 대사증후군, 비타민 D 결핍, 낙상 및 공포, 감염성 질환(예: 아나이티로박터 베르마니아 감염)의 위험 요인을 중심으로 연구를 진행하고 있습니다. 특히 한국의 도시와 농촌 노인을 대상으로 한 장기적 코hort 연구인 KURE(Korean Urban Rural Elderly)를 기반으로, 노화와 관련된 신체 기능, 생물학적 마커, 인지 기능 이상의 기전과 예방 전략을 다각도로 분석하고 있습니다. 연구는 임상적·사회적 요소를 융합하여 노화 관련 질환의 예방 및 관리 전략 수립에 기여하고자 합니다.

노화대사증후군비타민 D낙상장기 코hort 연구

연구 현황

논문 수
243
총 인용 수
3,129
최근 5년 논문
38
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
38총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
250총합
20222023202420252026

주요 논문

15
1
논문|인용수 67·2005
Mortality risk factors of Acinetobacter baumannii bacteraemia
Jun Yong Choi, Yoo Seok Park, Chang Oh Kim, Yoo Seok Park, Hee Jung Yoon, S. Y. Shin, Y.‐A. Kim, Young Goo Song, Dongeun Yong, Kyungwon Lee, J. M. Kim
SJR Q2Internal Medicine JournalOA

BACKGROUND: Acinetobacter baumannii is one of the most important nosocomial pathogens, and its multiple antibiotic resistance has emerged as an obstacle in the treatment of these infections worldwide. AIMS: To identify risk factors of mortality for A. baumannii bacteraemia. METHODS: A retrospective cohort study of 72 patients with significant A. baumannii bacteraemia was conducted to evaluate risk factors for mortality. RESULTS: The median age of the 72 enrolled patients was 48 years, 96% of the

Molecular MedicineBiochemistry, Genetics and Molecular Biology
2
논문|인용수 57·2011
Analysis of cellular senescence induced by lipopolysaccharide in pulmonary alveolar epithelial cells
Chang Oh Kim, Ae Jung Huh, Sang Hoon Han, June Myung Kim
SJR Q1Archives of Gerontology and Geriatrics
ImmunologyImmunology and Microbiology
3
논문|인용수 44·2014
The Korean urban rural elderly cohort study: study design and protocol
Eun Young Lee, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Kyoung Min Kim, Ju Mi Lee, Dong Phil Choi, Young Mi Yun, Chang Oh Kim
SJR Q1BMC GeriatricsOA

BACKGROUND: Korea is one of the fastest aging countries and is expected to become a super-aged society within 12 years. The Korean Urban Rural Elderly (KURE) study was developed to evaluate the epidemiological characteristics and establish the prevention and management of major disorders of the elderly in Korea. METHODS/DESIGN: The KURE study is a community-based prospective cohort study on health, aging, and common geriatric disorders of Korean elderly persons aged at least 65 years. To constru

General Health ProfessionsHealth Professions
4
논문|인용수 42·2016
Serum uric acid concentration and metabolic syndrome among elderly Koreans: The Korean Urban Rural Elderly (KURE) study
Hansol Choi, Hyeon Chang Kim, Bo Song, Ji Hye Park, Ju Mi Lee, Da-Lim Yoon, Young Mi Yoon, Yumie Rhee, Yousik Youm, Chang Oh Kim
SJR Q1Archives of Gerontology and GeriatricsOA
NephrologyMedicine
5
논문|인용수 40·2017
Falls, a fear of falling and related factors in older adults with complex chronic disease
JuHee Lee, MoonKi Choi, Chang Oh Kim
SJR Q1Journal of Clinical NursingOA

AIMS AND OBJECTIVES: To identify factors influencing falls and the fear of falling among older adults with chronic diseases in Korea. BACKGROUND: The fear of falling and falls in older adults are significant health problems towards which healthcare providers should direct their attention. Further investigation is needed to improve nursing practice specifically decreasing risk of falls and the fear of falling in Korea. DESIGN: Descriptive, cross-sectional survey. METHODS: A convenience sample of

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
6
논문|인용수 35·2015
Association between serum 25-hydroxyvitamin D concentrations and depressive symptoms in an older Korean population: A cross-sectional study
Bo Song, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Chang Oh Kim
SJR Q1Journal of Affective DisordersOA
Pathology and Forensic MedicineMedicine
7
논문|인용수 34·2019
Associations of serum 25-hydroxyvitamin D with metabolic syndrome and its components in elderly men and women: the Korean Urban Rural Elderly cohort study
Su Jin Lee, Eun Young Lee, Jung Hyun Lee, Jong‐Eun Kim, Kwang Joon Kim, Yumie Rhee, Hyeon Chang Kim, Yoosik Youm, Chang Oh Kim
SJR Q1BMC GeriatricsOA

BACKGROUND: Many studies have investigated the association between vitamin D and metabolic syndrome (MetS). However, few studies have investigated the association stratified by sex in the elderly. Therefore, we aimed to evaluate the association between vitamin D, MetS, and its components in Korean elderly men and women. METHODS: A total of 987 men and 1949 women aged ≥65 years were recruited through Korean Urban Rural Elderly cohort study. Serum 25-hydroxyvitamin D (25(OH)D) levels were categori

Pathology and Forensic MedicineMedicine
8
논문|인용수 28·2016
Association of metabolic syndrome and 25‐hydroxyvitamin D with cognitive impairment among elderly Koreans
Eun Young Lee, Su Jin Lee, Kyoung Min Kim, Young Mi Yun, Bo Song, Jong‐Eun Kim, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Chang Oh Kim
SJR Q2Geriatrics and gerontology international/Geriatrics & gerontology internationalOA

AIM: Metabolic syndrome and vitamin D deficiency are prevalent in older adults, and are considered risk factors for cognitive impairment. We investigated the combined effects of MetS and serum 25-hydroxyvitamin D (25[OH]D) levels on cognitive function in older adults. METHODS: We studied 2940 participants aged ≥65 years from the Korean Urban Rural Elderly cohort study. Metabolic syndrome was defined according to the updated Adult Treatment Panel III criteria. Serum 25(OH)D levels were categorize

Pathology and Forensic MedicineMedicine
9
논문|인용수 24·2019
Cohort profile: Korean Urban Rural Elderly (KURE) study, a prospective cohort on ageing and health in Korea
Namki Hong, Kwang-Joon Kim, Su Jin Lee, Chang Oh Kim, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Jin‐Young Choi, Hyun‐Young Park
SJR Q1BMJ OpenOA

PURPOSE: The Korean Urban Rural Elderly (KURE) cohort was initiated to study the epidemiologic characteristics, physical performance, laboratory and imaging biomarkers and incidence of age-related diseases in an elderly population with respect to both clinical and social aspects to develop preventive and therapeutic strategies for combatting age-related diseases. PARTICIPANTS: A total of 3517 adults aged 65 or older participated in the cohort at baseline from 2012 to 2015, recruited from three u

HealthSocial Sciences
10
논문|인용수 22·2017
Older Adults With Hip Arthroplasty: An Individualized Transitional Care Program
YoungJi Ko, JuHee Lee, Eui Geum Oh, Mona Choi, Chang Oh Kim, Kiwol Sung, Seung‐Hoon Baek
SJR Q3Rehabilitation NursingOA

BACKGROUND: Most older adults with hip fracture surgery experience functional decline (FD), causing devastating outcomes. However, few studies have examined the effects of nursing interventions to reduce FD for them. PURPOSE: The aim of the study was to evaluate an individualized transitional care program (ITCP) to reduce FD for older adults with hip arthroplasty. METHODS: The study was quasiexperimental, with a nonequivalent control group design. A total of 37 participants scheduled for hip art

SurgeryMedicine
11
논문|인용수 20·2008
LPS-INDUCED VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION IN RAT LUNG PERICYTES
Chang Oh Kim, Ae Jung Huh, Myoung Soo Kim, Bum Sik Chin, Sang Hoon Han, Suk Hoon Choi, Su Jin Jeong, Hee Kyoung Choi, Jun Yong Choi, Young Goo Song, June Myung Kim
SJR Q1ShockOA

Vascular endothelial growth factor (VEGF) is a potent angiogenic and vascular permeability factor. Recent studies have shown that the VEGF levels increase in several cell types, for example, macrophages and smooth muscle cells after LPS stimulation, suggesting that it is important in the initiation and development of sepsis. In particular, LPS-regulated contractility in lung pericytes may play an important role in mediating pulmonary microvascular fluid hemodynamics during sepsis. This study inv

Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
논문|인용수 19·2013
Evaluation of humoral immune response to nosocomial pathogen and functional status in elderly patients with sepsis
Su Jin Jeong, Sang Sun Yoon, Sang Hoon Han, Dong Yong, Chang Oh Kim, June Myung Kim
SJR Q1Archives of Gerontology and GeriatricsOA
Critical Care and Intensive Care MedicineMedicine
13
논문|인용수 19·2014
Association between skeletal muscle mass and radial augmentation index in an elderly Korean population
Seung Won Lee, Yoosik Youm, Chang Oh Kim, Won Joon Lee, Wungrak Choi, Sang Hui Chu, Yeong-Ran Park, Hyeon Chang Kim
SJR Q1Archives of Gerontology and GeriatricsOA
Cardiology and Cardiovascular MedicineMedicine
14
논문|인용수 19·2017
Association between HbA1c and carotid atherosclerosis among elderly Koreans with normal fasting glucose
Seung Won Lee, Hyeon Chang Kim, Yong‐ho Lee, Bo Song, Hansol Choi, Ji Hye Park, Yumie Rhee, Chang Oh Kim
SJR Q1PLoS ONEOA

HbA1c levels were positively associated with carotid atherosclerosis, as assessed by carotid IMT, in an elderly population with normoglycemia. Our study suggested that higher HbA1c level is an effective and informative marker of carotid atherosclerosis in an elderly population.

Cardiology and Cardiovascular MedicineMedicine
15
논문|인용수 18·2015
Anti-cytomegalovirus antibody levels are associated with carotid atherosclerosis and inflammatory cytokine production in elderly Koreans
Su Jin Jeong, Nam Su Ku, Sang Hoon Han, Jun Yong Choi, Chang Oh Kim, Young Goo Song, June Myung Kim
SJR Q1Clinica Chimica ActaOA
EpidemiologyMedicine

대표 연구 분야

EpidemiologyPhysiologyInfectious DiseasesGeriatrics and GerontologySurgeryEmergency Medicine

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