이철민 교수

BACKGROUND: This paper describes the background, aim, and design of a prospective birth-cohort study in Korea called the COhort for Childhood Origin of Asthma and allergic diseases (COCOA). COCOA objectives are to investigate the individual and interactive effects of genetics, perinatal environment, maternal lifestyle, and psychosocial stress of mother and child on pediatric susceptibility to allergic diseases. METHODS/DESIGN: The participants in COCOA represents a Korean inner-city population.

We report a new approach for the detection of ochratoxin A (OTA) by introducing surface-enhanced Raman scattering (SERS). This method is based on different adsorption propensities of Raman reporter Cy5-tagged OTA aptamer. The OTA aptamer could be easily adsorbed onto the surface of silver nanoparticles (AgNPs) to give fairly strong SERS signals, whereas such bindings would be hampered in the presence of OTA. On the addition of OTA in the concentration range of 0.1–10 nM, the SERS signals appeare

본 연구는 일반인들이 많이 이용하고 있는 다중이용시설의 실내공기중의 바이오에어로졸의 농도분포 및 건축물의 특성에 따른 분포 특성을 제시하고자 2002년 12월부터 2003년 2월까지 서울시에 위치한 불특정 다수인이 이용하는 다중이용시설 13곳(극장, 지하철, 유치원, 구청, 도서관, 박물관, 터미널, 주택, 병원, 아파트)을 대상으로 실내공기중 바이오에어로졸을 독일 Bio test사의 RCS 및 미국 Andersen사의 Six-stage cascade air sampler를 이용하여 시료를 포집, 분석하여 그 결과를 제시하였으며, 또한 산출된 결과를 바탕으로 건축물의 특성에 따른 분포 특성을 조사한 결과 다음과 같은 결론을 도출하였다.1) 다중이용시설의 실내외 공기중 RCS를 이용한 박테리아의 평균농도는 각각 378.08 296.33 CFU/m3, 193.83 116.64 CFU/m3, 곰팡이의 평균농도는 각각 106.38 171.63 CFU/m3, 84.91 55.44 CFU/m3

Surface-enhanced Raman scattering (SERS) of an antifungal reagent, myclobutanil (MCB), was performed on Au and Ag nanoparticles (NPs) to estimate the drug-release behaviors in fungal cells. A density functional theory (DFT) calculation was introduced to predict a favorable binding site of MCB to either the Ag or Au atom. Myclobutanil was presumed to bind more strongly to Au than to Ag in their most stable, optimized geometries of the N4 atom in its 1,2,4-triazole unit binding to the metal atom.

Currently, Ministry of Environment has promu lgated and executed 'the legislation of indoor air quality for public facilities' but the data of indoor air pollutant for public facilities of this law was very insufficient. Therefore, collection of data for indoor air pollutants and execution for risk ass essment in order to offer scientific data for decision-making of policy to present reasonable standards and preventive techniques of engineering were required. Therefore, this study collected and

The objective of this study was to offer basic and scientific data for decision-making of policy for improvement and management of radon, natural radiation gas, in Korea and to form the foundation of radon related international cooperation. Therefore, this study collected and re-analysed the articles on exposure of radon in various indoor environment in journals related environment in Korea since 1980 and estimated the annual exposure dose and effective dose by exposure of radon received by inha

The radon concentrations were measured to survey distribution of radon concentrations in Seoul subway stations. The radon concentrations in air and water were measured at seventeen subway stations(Mapo, Chungjongno, Sodaemun, Kwanghwamun, Chongno3ga, Ulchiro4ga, Tangdaemun, Sangildong on Line 5;Nowon, Chunggye, Hagye, Kongnung, Taenung, Mokkol, Chunghwa, Sangbong, Myomok on Line 7) using the RAdtrakTM radon gas detector, Pylon AB-5 continuous passive radon detector and liquid scintillation count

The objective of this study is to offer basic scientific data to support policy decision-making for the improved control of suspended microorganism and to provide baseline data in order to improve the studies of bioaerosol in Korea. Therefore, this study collected and re-analyzed articles on suspended microorganism in various indoor environments and atmospheric environment in Korea that were published in environmental journals since 1980. The survey on the bioaerosol concentration in hospital am

The adverse health effects of a number of environment pollutions are related to the formation of free radicals. Induction of antioxidant defensive system in the response to an oxidative attack is an essential element of the cell to survive. CYP2E1 is easily induced by organic solvents and induces continuous formation of reactive oxygen species (ROS). g-Glutamyltranspeptidase (gGT) plays an important role in glutathione metabolism and xenobiotic detoxification. To evaluate the characteristic of o

제시하면 다음과 같다.첫째 사무실의 실내공기 중 호흡성분,12 이철민 김윤신 노영만 김종철 전형진 이소담 진의 병합평균농도는 114 84 /m㎍3일,산화탄소는 21.6 이산화탄소는 ppm,1,008 983 로 조사되었으며 이들 중 ppm ,이산화탄소만이 산업보건기준에서 정하고 있는 기준치를 초과하고 있는 것으로조사되었다.둘째 휘발성유기화합물질의 사무실 ,내공기 중 병합평균농도는 은Benzene11.1 13.1 /m㎍3 은 , Toluene 65,8 79.8㎍/m3은 , Ethylbenzene 7.7 9.3 /m㎍3,은 m-p-Xylene 23.1 25.6 /m㎍3 은 , S t y l e n e5.5 5.2 /m㎍3 은 , o-Xylene 14.6 17.9㎍/m3로 조사되었다.셋째 기준공기오염물질에 대한 몬테카,를로 분석을 이용한 건강위해성평가 결과호흡성분진 및 이산화탄소의 안전계수가을 초 과 할 확 률 이 각 각1 36.83%, 99.12%로 사무실 실내공기중 이들 두 오염물질에