김대덕 교수
Dae Duk Kim
서울대학교 의약학과 · 의학
연구실 소개
김대덕 교수의 연구실은 약물 전달 시스템의 최적화를 핵심으로 하여, 특히 난소성 약물의 생체내 행동과 조직 특이적 배달을 향한 기초 및 응용 연구를 수행하고 있습니다. 도xorubicin의 약물학적 특성과 투여 경로에 따른 생체이용률, 그리고 라이피오도르-기반 에멀전과 약물-적재 나노입자(예: NLC)를 활용한 피부 치료제 개발 등 다양한 약물 전달 전략을 연구하고 있습니다. 특히, 종양 치료를 위한 동물 모델 기반의 약물 방출 프로파일링과 약물 농도-반응 관계 분석을 통해 임상 적용 가능성을 탐색하고 있습니다.
약물 전달 시스템나노입자도xorubicin피부 치료동물 모델
연구 현황
논문 수
383
총 인용 수
13,191
최근 5년 논문
34
주요 분야
의학
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
5개년 연도별 논문 게재 수
34총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
372총합
20222023202420252026
주요 논문
151
논문|인용수 386·2007
Enhanced solubility and stability of PEGylated liposomal paclitaxel: In vitro and in vivo evaluationYang Tao, Fu-De Cui, Min-Koo Choi, Jei-Won Cho, Suk-Jae Chung, Chang-Koo Shim, Dae‐Duk Kim
SJR Q1International Journal of Pharmaceutics
BiomaterialsMaterials Science
2
논문|인용수 365·2011
A novel vesicular carrier, transethosome, for enhanced skin delivery of voriconazole: Characterization and in vitro/in vivo evaluationChung Kil Song, Prabagar Balakrishnan, Chang‐Koo Shim, Suk-Jae Chung, Saeho Chong, Dae‐Duk Kim
SJR Q1Colloids and Surfaces B Biointerfaces
Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
3
논문|인용수 302·2009
Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluationYongmei Yin, Fude Cui, Chaofeng Mu, Min-Koo Choi, Jung‐Sun Kim, Suk‐Jae Chung, Chang‐Koo Shim, Dae‐Duk Kim
SJR Q1Journal of Controlled Release
Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
4
논문|인용수 302·2011
Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic® for tumor-targeted delivery of docetaxelHyun‐Jong Cho, Hong Yeol Yoon, Heebeom Koo, Seung-Hak Ko, Jae-Seong Shim, Juhee Lee, Kwangmeyung Kim, Ick Chan Kwon, Dae‐Duk Kim
SJR Q1Biomaterials
BiomaterialsMaterials Science
5
논문|인용수 241·2007
Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposomeYang Tao, Min‐Koo Choi, Fude Cui, Jung‐Sun Kim, Suk‐Jae Chung, Chang‐Koo Shim, Dae‐Duk Kim
SJR Q1Journal of Controlled Release
Radiology, Nuclear Medicine and ImagingMedicine
6
논문|인용수 220·2013
Hyaluronic acid derivative-coated nanohybrid liposomes for cancer imaging and drug deliveryJu-Hwan Park, Hyun‐Jong Cho, Hong Yeol Yoon, In‐Soo Yoon, Seung-Hak Ko, Jae-Seong Shim, Jee-Hyun Cho, Jae Hyung Park, Kwangmeyung Kim, Ick Chan Kwon, Dae‐Duk Kim
SJR Q1Journal of Controlled Release
BiomaterialsMaterials Science
7
논문|인용수 180·2010
The effects of mixed MPEG–PLA/Pluronic® copolymer micelles on the bioavailability and multidrug resistance of docetaxelChaofeng Mu, Prabagar Balakrishnan, Fude Cui, Yongmei Yin, Yong‐Bok Lee, Han-Gon Choi, Chul Soon Yong, Suk‐Jae Chung, Chang‐Koo Shim, Dae‐Duk Kim
SJR Q1Biomaterials
BiomaterialsMaterials Science
8
논문|인용수 156·2006
Air-Liquid Interface (ALI) Culture of Human Bronchial Epithelial Cell Monolayers as an in vitro Model for Airway Drug Transport StudiesHongxia Lin, Hong Li, Hyun‐Jong Cho, Shengjie Bian, Hwan‐Jung Roh, Minki Lee, Jung‐Sun Kim, Suk-Jae Chung, Chang‐Koo Shim, Dae‐Duk Kim
SJR Q1Journal of Pharmaceutical Sciences
Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 142·2015
Phenylboronic Acid‐Decorated Chondroitin Sulfate A‐Based Theranostic Nanoparticles for Enhanced Tumor Targeting and PenetrationJae‐Young Lee, Suk‐Jae Chung, Hyun‐Jong Cho, Dae‐Duk Kim
SJR Q1Advanced Functional Materials
Phenylboronic acid‐functionalized chondroitin sulfate A (CSA)–deoxycholic‐acid (DOCA)‐based nanoparticles (NPs) are prepared for tumor targeting and penetration. (3‐Aminomethylphenyl)boronic acid (AMPB) is conjugated to CSA–DOCA conjugate via amide bond formation, and its successful synthesis is confirmed using proton nuclear magnetic resonance spectroscopy ( 1 H‐NMR). Doxorubicin (DOX)‐loaded CSA–DOCA–AMPB NPs with a mean diameter of ≈200 nm, a narrow size distribution, negative zeta potential,
Biomedical EngineeringEngineering
10
논문|인용수 120·2007
Antitumor Effect of Paclitaxel-Loaded PEGylated Immunoliposomes Against Human Breast Cancer CellsYang Tao, Min-Koo Choi, Cui Fu-de, Seung Jin Lee, Suk-Jae Chung, Chang-Koo Shim, Dae‐Duk Kim
SJR Q1Pharmaceutical Research
BiomaterialsMaterials Science
11
논문|인용수 113·2012
Chitosan oligosaccharide–arachidic acid-based nanoparticles for anti-cancer drug deliveryUbonvan Termsarasab, Hyun‐Jong Cho, Dong‐Hwan Kim, Dong‐Hwan Kim, Saeho Chong, Suk‐Jae Chung, Chang‐Koo Shim, Hyun Tae Moon, Dae‐Duk Kim, Dae‐Duk Kim
SJR Q1International Journal of Pharmaceutics
BiomaterialsMaterials Science
12
논문|인용수 105·2016
Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug deliveryJae‐Young Lee, Ubonvan Termsarasab, Ju-Hwan Park, Song Yi Lee, Seung-Hak Ko, Jae-Seong Shim, Suk-Jae Chung, Hyun‐Jong Cho, Dae‐Duk Kim
SJR Q1Journal of Controlled Release
BiomaterialsMaterials Science
13
논문|인용수 92·2006
Enhancing effect of surfactants on fexofenadine·HCl transport across the human nasal epithelial cell monolayerHongxia Lin, Matthias Gebhardt, Shengjie Bian, Kyoung Ae Kwon, Chang‐Koo Shim, Suk-Jae Chung, Dae‐Duk Kim
SJR Q1International Journal of Pharmaceutics
OncologyMedicine
14
논문|인용수 91·2018
Curcumin-loaded lipid-hybridized cellulose nanofiber film ameliorates imiquimod-induced psoriasis-like dermatitis in miceNae‐Won Kang, Min Hwan Kim, Seo-Yeon Sohn, Ki-Taek Kim, Ju-Hwan Park, Sun-Young Lee, Jae‐Young Lee, Dae‐Duk Kim
SJR Q1Biomaterials
Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
15
논문|인용수 85·2011
Proliferation and chondrogenic differentiation of human adipose-derived mesenchymal stem cells in porous hyaluronic acid scaffoldIn‐Soo Yoon, Chung Wook Chung, Jong-Hyuk Sung, Hyun‐Jong Cho, Jung‐Sun Kim, Won‐Sik Shim, Chang-Koo Shim, Suk-Jae Chung, Dae‐Duk Kim
SJR Q2Journal of Bioscience and Bioengineering
GeneticsMedicine
대표 연구 분야
Pharmaceutical ScienceBiomaterialsOncologyMolecular BiologyPharmacologyOrganic Chemistry
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