조도상 교수
Do-sang Cho
이화여자대학교 의학과 · 의학
연구실 소개
조도상 교수의 연구실은 척추 및 말초신경 손상, 특히 척수병변과 주의 신경 손상의 기전과 치료에 중점을 두고 있습니다. 고령 환자나 체질적 소인을 가진 환자에서 발생하는 후견선 연골화증(OPLL)의 병태생리학적 원인과 신경학적 증상의 진행 메커니즘을 규명하고자 하며, 수술적 접근과 재활 전략의 최적화를 목표로 하고 있습니다. 또한, 척추외과 수술 시 발생할 수 있는 신경병변(예: 갈비신경 손상)의 해부학적 기반을 규명하고, 이를 바탕으로 합병증을 최소화하는 수술 기법 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15Ossification of the posterior longitudinal ligament (OPLL) is most commonly found in men, the elderly, and Asian patients. There are many diseases associated with OPLL, such as diffuse idiopathic skeletal hyperostosis, ankylosing spondylitis, and other spondyloarthropathies. Several factors have been reported to be associated with OPLL formation and progression, including genetic, hormonal, environmental, and lifestyle factors. However, the pathogenesis of OPLL is still unclear. Most symptomatic
OBJECT: This study analyzes 84 cases of peroneal nerve injuries associated with sports-related knee injuries and their surgical outcome and management. METHODS: The authors retrospectively reviewed the cases of peroneal nerve injury associated with sports between the years 1970 and 2010. Each patient was evaluated for injury mechanism, preoperative neurological status, electrophysiological studies, lesion type, and operative technique (neurolysis and graft repair). Preoperative status of injury
OBJECT: The thoracolumbar junction is frequently accessed through an anterolateral approach with the incision and muscle dissection extending from the lower thoracic region to the lateral border of the rectus abdominis muscle. This approach is frequently associated with the subsequent development of an unsightly and uncomfortable relaxation of the ipsilateral abdominal wall, or flank bulge, caused by denervation injury to the intercostal nerves. However, the etiology of this complication is not
hospital and was classified as grade 1. An examination found hypoesthesia at the T8 level and below and the deep tendon reflexes were reduced. We performed a chest computed tomography (CT) scan, but aortic dissection was not observed. We suspected hypokalemic periodic paralysis of both lower extremities and conducted laboratory studies; however, the results were negative. We then suspected thoracic myelopathy and thus provided steroid mega-dose therapy and conducted magnetic resonance imaging (M
A domain-specific multimodal generative AI model demonstrated potential for high diagnostic accuracy and clinical value in providing preliminary interpretations of chest radiographs for radiologists.
OBJECT: Anterior surgical approaches to the lumbosacral disc spaces are being undertaken with increasing frequency. This increase and the use of minimally invasive techniques themselves have the potential to raise the incidence of major vessel injuries. The purpose of this study was to determine the variability of the vascular anatomy anterior to the lumbosacral spine and to draw conclusions regarding surgical accessibility of the L5-S1 disc space. METHODS: Thirty-five cadavers (age range at the
Arthroplasty using the Bryan(R) disc seemed to be safe and provided encouraging clinical and radiologic outcome in our study. Although the early results are promising, this is a relatively new approach, therefore long-term follow up studies are required to prove its efficacy and its ability to prevent adjacent segment disease.
Iatrogenic vascular injuries during lumbar disc surgery may occur rarely but they are serious complications, which can be fatal without appropriate management. Prompt diagnosis and management of these complications are imperative to prevent a desperate outcome. A 72-year-old female with proximal left common iliac artery iatrogenic injury during lumbar discectomy was successfully treated by percutaneous deployment of a stent graft in an emergency setting. Postprocedural angiogram demonstrated com
The Mayfield head clamp is the most frequently used head clamp system in the field of neurosurgery. In many cases, surgery is performed with complete reliance on the safety of the MHC. However, we experienced an extremely rare case in which the MHC accidentally broke while installing this system for immobilization of the head and neck. This is a case report with a brief review of the literature. The patient was a 58-year-old female who was scheduled to undergo cervical laminoplasty under the dia
Spinal subdural hematoma (SSDH) is an extremely uncommon condition. Causative factors include trauma, anticoagulant drug administration, hemostatic disorders, and vascular disorders such as arteriovenous malformations and lumbar punctures. Of SSDH cases, those that do not have any traumatic event can be considered cases of nontraumatic acute spinal subdural hematoma, which is known to have diverse clinical progress. Treatment typically consists of surgical decompression and cases in which the co
Objective : Recently, motion preservation has come to the forefront of emerging technologies in spine surgery. This is the important background information of the emergence of cervical arthroplasty as an alternative to arthrodesis that offers the promise of restoring normal spinal movement and reduces a kinematic strain on adjacent segments. The study was designed to evaluate early surgical outcome and radiological effects of Bryan® cervical disc prosthesis. Methods : The authors retrospectively
These biomechanical findings indicate that the rigidity of the dynamic stabilization implant and physiological loading play significant roles on spinal kinematics at adjacent disc levels, and will aid in further device development.
This study aimed to investigate mental illnesses among patients with hemifacial spasms (HFS) based on nationwide claims data from the South Korea Health Insurance Review and Assessment Service. In this retrospective study, we defined the HFS group as subjects aged between 20 and 79 years with newly diagnosed HFS between January 2011 and December 2019 and set the date of diagnosis of HFS as the index date. Mental illnesses were defined through the International Classification of Diseases, the ten
Chordoma is an extremely rare tumor and makes up 1% of the whole malignant tumors and 0.1~0.2% of intracranial tumors. Approximately half are in sacrococcygeal region, 35% in the base of skull, and 15% in vertebrae. Moreover, chordoma in sellar region is considered to be rarer, and most of the cases show non-specific symptoms such as headache, ophthalmodynia, diplopia, and amblyopia. The tumor looks very similar to pituitary adenoma in radiographic images, and therefore, clinicians may make a mi
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