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Scale-resolving simulations (SRSs) such as large-eddy simulation (LES) and hybrid LES/Reynolds-averaged Navier–Stokes are applied to analyze the unsteady characteristics of the drag and flow fields for blunt bodies subject to impulsive motion. These simulations reveal highly transient behaviors of the primary and secondary vortices triggered by inertial forces during impulsive motion. A distinctive characteristic of the transient drag, namely, the existence of a plateau region, induced by a circ

Pattern recognition receptors (PRRs) in innate immune cells play a pivotal role in the first line of host defense system. PRRs recognize pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs) to initiate and regulate innate and adaptive immune responses. PRRs include Toll-like receptors (TLRs), RIG-I-like receptors (RLRs) and NOD-like receptors (NLRs), which have their own features in ligand recognition and cellular location. Activated PRRs deliver signals

INTRODUCTION: Most ectopic sebaceous glands have been reported in the tissues of ectodermal origin. However, there are relatively a few reports of ectopic sebaceous glands in the oesophagus, an organ of endodermal origin. CASE PRESENTATION: We report the case of an asymptomatic 54-year-old man with ectopic oesophageal sebaceous glands. These lesions were incidentally observed in the distal oesophagus during screening endoscopy of gastric neoplasm and confirmed by histologic analysis. CONCLUSION:

Numerical predictions of fan noise have not been studied extensively. This is due to the scattering effect of the fan casing, duct and the difficulty in obtaining aerodynamic acoustic source. New method to predict the fan noise and performance is developed and used to calculate various fan noise problems. A vortex method is used to model the fan and to calculate the flow field. Acoustic pressures are obtained from the unsteady force fluctuations of the blades using an acoustic analogy. But the a