윤을식 교수

Recent studies suggest that human adipose tissue contains pluripotent stem cells, which are similar to bone marrow-derived stem cells. The objective of the present study was to assess the effect in bone regenerating capability of human adipose-derived stem cells (ADSCs) cultured in osteogenic media layered over poly lactide-co-glycolic acid (PLGA) and implanted in a critical nude rat calvarial defect. Twenty-seven nude rats were randomized into 3 groups (n = 9): 1) PLGA alone (control), 2) PLGA

There are several different imaging methods that are helpful in the diagnosis of carpal tunnel syndrome, including traditional radiography, computed tomography (CT), and magnetic resonance imaging (MRI). CT and MRI offer the advantage of providing direct visualization of the structural abnormality of the carpal tunnel and median nerve, but both of these modalities are expensive and time-consuming. Recently, high-resolution ultrasonography has been reported to be effective in the study of the mus

The authors evaluated the morphologic changes that follow division of the transverse carpal ligament in patients with carpal tunnel syndrome (CTS) using high-resolution ultrasonography. Ten patients, for a total of 20 hands, underwent high-resolution ultrasonographic studies before the operation and 8 months after the operation. They were all diagnosed with bilateral idiopathic CTS. The authors evaluated the configuration of the median nerve and carpal tunnel at 3 different levels of the wrist:

Although many studies have suggested that human adipose tissue contains pluripotent stem cells, a few reports are available on stromal vascular fraction (SVF). In the present study, we evaluated the bone formation capacities of SVF. We implanted uncultured freshly isolated adipose-derived stem cells combined with demineralized bone matrix (DBM) to induce bone regeneration in a critically sized rat calvarial defect model. We used DBM (DBX(®)) and/or poly(70L-lactide-co-30DL-lactide) copolymer PLA

For the elimination of facial wrinkles and skin contour defects, injectable filler substances composed of commercially prepared nonanimal stabilized hyaluronic acid (Restylane) are now widely used. Although this method of suspension has been shown to be relatively safe and convenient, varying degrees of resorption have required repeated percutaneous injections. This study was undertaken to evaluate the feasibility of Restylane, which is a modified hyaluronic acid, combined with cultured human de

A prominent mandibular angle is considered to be unattractive in Asians because it gives the face a square, coarse, and muscular appearance. Asian women desire to have an ovoid, reduced, and slender face by aesthetic mandibular angle resection. Mandibular angle ostectomy has been known to be effective and to satisfy both surgeons and patients. Especially in Korea, it has become as popular as facial bone contouring surgery, which reduces lower facial width. However, a narrow surgical field hinder

Our results suggested that ILR may be a promising surgical treatment to prevent postoperative lymphedema. There is a need for larger studies with longer follow-up to confirm the findings obtained in our study.

Several investigators have reported their clinical experience with medial pedis flaps for reconstruction of soft tissue defects of the hand and digits. In a cadaveric study in 1997, Jayme and Hamilton described the anatomy of the medial branch of the deep division of the medial plantar artery, which is used in the medial pedis flap. However, they had only a few cases where this flap was used. There have been no such anatomic studies in Korea to date. We found the medial pedis flap to be a reliab

With the advancement of trichloroacetic acid peel technology and wound care, trichloroacetic acid peeling has become very successful in Korea. Its success has opened studies on the possibility of using phenol on Korean skin. Dr. Mee's phenol formula (molding mask technique) was chosen for experiments on Korean skin because of the presumed safety of use on non-Caucasian skin. Between January of 1996 and January of 1998, 30 cases of significant small pox scars were treated with phenol at the Korea

The combined approach showed a significant decrease in the circumference of LEL. Additional LVAs could reinforce the effect of a VLNT. Larger series with longer follow-up is needed to confirm our findings.