이은화 교수
Eun-Hwa Lee
이화여자대학교 의학과 · 의학
연구실 소개
이은화 교수의 연구실은 식물-균 상호작용, 특히 아큐부라스 미세균류와 식물 간의 공진화 관계를 중심으로 한 생태학적·분자생물학적 연구를 수행합니다. 동시에 임상에서의 감염 및 염증 반응 평가, 특히 CRP, PCT, IL-6 등의 생체마커크터를 통한 조기 진단 기반의 감염성 질환 연구도 진행하고 있습니다. 특히 심각한 질환 환자에서의 혈행감염, ECMO 연관 감염, HIV 환자에서의 비결핵균 감염 등 임상적 난이도 높은 감염성 질환의 역학과 병원체 특성에 대한 종합적 분석도 핵심 과제입니다. 이와 더불어 농업 및 에너지 분야에서의 촉매 기반 바이오오일 생산 기술 개발도 함께 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Arbuscular mycorrhizal fungi (AMF) have mutualistic relationships with more than 80% of terrestrial plant species. This symbiotic relationship is ancient and would have had important roles in establishment of plants on land. Despite their abundance and wide range of relationship with plant species, AMF have shown low species diversity. However, molecular studies have suggested that diversity of these fungi may be much higher, and genetic variation of AMF is very high within a species and even wi
C-reactive protein (CRP) or procalcitonin (PCT) alone has limitations in the early detection of infection or inflammation due to shortcomings in specificity and varied cut-off values. Recently, interleukin (IL)-6 has been assessed, but it is not known to what extent the three values are homogeneous in reality. This retrospective study was conducted with two large datasets (discrepancy set with results within 24 h of admission [7149 patients] and follow-up set until 2 weeks of hospital stay [5261
Extracorporeal membrane oxygenation (ECMO) provides hemodynamic and oxygenation support to critically ill patients. Due to multiple catheter cannulations, patients on ECMO are vulnerable to bloodstream infections (BSIs). We aimed to investigate the incidence, clinical characteristics, risk factors, and microorganisms associated with BSIs during ECMO. This single-center retrospective cohort study was conducted between January 2015 and May 2021. Patients aged 18 years or older with an ECMO duratio
With the introduction of combination antiretroviral therapy (cART), the prevalence of human immunodeficiency virus (HIV)-associated nontuberculous mycobacteria (NTM) disease has declined. However, NTM diseases still occur in people living with HIV/acquired immunodeficiency syndrome (AIDS) (PLWHA). We analysed the clinical and microbiological features of NTM diseases in PLWHA in South Korea. PLWHA who were diagnosed with NTM diseases between January 2000 and March 2021 were retrospectively enroll
Various SBA-15-based catalysts, Si-SBA-15, Pt/Si-SBA-15, Al-SBA-15, and Pt/Al-SBA-15, were applied to the catalytic pyrolysis of miscanthus. Pt nanoparticles with three different sizes, 1.7 nm, 2.9 nm, and 7.1 nm, were used to synthesize Pt/Si-SBA-15 and Pt/Al-SBA-15. Pyrolysis-gas chromatography/mass spectrometry was used for the pyrolysis experiments. The catalysts were characterized by X-ray diffraction patterns, transmittance electron microscopy, N2 adsorption-desorption, and Brunaure-Emmett
BACKGRUOUND: The mortality of sepsis without direct drugs is high. The association between prediabetes, based on a single fasting glucose (FG), or long-term type 2 diabetes mellitus (T2DM) and sepsis remains unclear. METHODS: Of the adults aged ≥20 years who were included in the National Health Screening Program (NHSP) in 2009, 40% were randomly sampled. After excluding patients with type 1 diabetes mellitus, with missing information, and who were diagnosed with sepsis during the wash-out (betwe
BACKGROUND: Trichosporon is an emerging yeast that causes invasive infections in immunocompromised patients experiencing prolonged hospitalisation, indwelling venous catheters and neutropenia. METHODS: This retrospective observational cohort study analysed invasive Trichosporon infections (ITIs) occurring between January 2005 and December 2022 at three tertiary hospitals and compared the clinical characteristics and prognostic factors of ITIs caused by Trichosporon asahii and non-T. asahii spp.
BACKGROUND: Sepsis remains a growing global health concern with soaring mortality and no direct anti-sepsis drug. Although smoking has distinct deleterious effects on chronic inflammatory illnesses and can impair immune function, a comprehensive analysis of the connection between sepsis and smoking is lacking. METHODS: This large-scale longitudinal cohort study retrospectively assessed adults aged ≥ 20 years who underwent national health checkups under the Korean National Health Insurance Servic
PEKIs and their weights can be utilized for impartial evaluation and MBO for hospital nurses. Further research to verify PEKIs would lead to successful implementation of MBO.
본 연구는 우리나라 최초의 유치원인 이화여자대학교 사범대학 부속 이화유치원의 교육과정을 구성하고 있는 이론적 근거를 역사적, 철학적으로 고찰하는 것을 그 목적으로 하였다. 본 연구는 문헌연구를 통하여 이화유치원 설립 당시부터 현재까지의 교육과정의 성립 및 변천과정과 철학적, 심리적 사조를 살펴보고 이들의 영향이 이화유치원 교육과정에 나타난 부분을 탐구하였다. 연구결과 1914년 한 미국인 선교사에 의해 설립된 이화여자대학교 사범대학 부속 이화유치원은 설립 이후 지금까지 우리나라 유치원 교육의 모델을 제시하며 선도적 역할을 담당해오고 있음을 알 수 있었다. 교육과정의 측면에서는 유아들의 전인발달 특히 사회, 정서적인 발달을 중요시하고 우리의 전통사상과 기독교정신, 진보주의 이론 및 구성주의가 그 철학적, 심리적 기초를 이루고 있음을 알 수 있었다.
Abstract Background Extracorporeal membrane oxygenation (ECMO) provides hemodynamic and oxygenation support to critically ill patients. Due to multiple catheter cannulations, patients on ECMO are vulnerable to bloodstream infections (BSIs). We aimed to investigate the incidence, clinical characteristics, risk factors, and microorganisms associated with BSIs during ECMO. Methods This single-center retrospective cohort study was conducted between January 2015 and May 2021. Patients aged 18 years o
Dehydroepiandrosterone (DHEA) is an adrenal steroid converted to potent androgens. This study aimed to discover the association between serum DHEA levels and immunologic response in people with HIV/AIDS (PLWHA). We enrolled patients aged ≥ 18 years who were treated with combination antiretroviral therapy (cART). We measured CD4+ and CD8+ T-cell counts, HIV-RNA titres, and serum DHEA levels. We assigned each patient to a good- or poor-responder group depending on their CD4+ T-cell counts at study
대표 연구 분야
이은화 교수의 연구를 Nubint에서 더 깊이 살펴보세요
이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.