김은희 교수

<b>Objective: </b> Migraine carries an increased risk for cardiovascular and cerebrovascular diseases that cannot be explained by traditional cardiovascular risk factors. The circulating endothelial progenitor cell (EPC) number is a surrogate biologic marker of vascular function, and diminished EPC counts are associated with higher cardiovascular risk. We investigated whether abnormalities in EPC levels and functions are present in migraine patients. <b>Methods: </b> Consecutive headache patient

In order to study the $\ensuremath{\Sigma}$-nucleus optical potential, we measured inclusive $({\ensuremath{\pi}}^{\ensuremath{-}},{K}^{+})$ spectra on medium-to-heavy nuclear targets $\mathrm{C}{\mathrm{H}}_{2}$, Si, Ni, In, and Bi. The $\mathrm{C}{\mathrm{H}}_{2}$ target was used to calibrate the excitation energy scale by using the elementary process $p+{\ensuremath{\pi}}^{\ensuremath{-}}\ensuremath{\rightarrow}{K}^{+}+{\ensuremath{\Sigma}}^{\ensuremath{-}}$, where the C spectrum was also ext

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransition state spectroscopy of the OH + H2 .fwdarw. H2O + H reaction via photodetachment of H3O- and D3O-E. de Beer, E. H. Kim, D. M. Neumark, R. F. Gunion, and W. C. LinebergerCite this: J. Phys. Chem. 1995, 99, 37, 13627–13636Publication Date (Print):September 1, 1995Publication History Published online1 May 2002Published inissue 1 September 1995https://pubs.acs.org/doi/10.1021/j100037a009https://doi.org/10.1021/j100037a009research-articleACS Publi

We performed a coincidence measurement of two nucleons emitted from the nonmesonic weak decay of $_{\ensuremath{\Lambda}}^{5}\mathrm{He}$ formed via the $^{6}\mathrm{Li}({\ensuremath{\pi}}^{+},{K}^{+})$ reaction. The energies of the two nucleons and the pair number distributions in the opening angle between them were measured. In both $np$ and $nn$ pairs, we observed a clean back-to-back correlation coming from the two-body weak reactions of $\ensuremath{\Lambda}p\ensuremath{\rightarrow}np$ and

Objective: Our goals were to determine the added value of fine-needle aspiration biopsy (FNAB)-thyroglobulin (Tg) measurements over FNAB-cytology alone for diagnosing metastatic nodes, and to determine whether the ultrasound features of lymph nodes can be used to identify lymph nodes that may benefit from FNAB-Tg measurement in patients with papillary thyroid cancer. Materials and Methods: We retrospectively evaluated 76 surgically proven cervical lymph nodes. Twenty-nine patients were awaiting

Ginsenosides, ingredients of ginseng, have a wide array of pharmacologic effects. Especially, ginsenosides Rk1, Rg3, and Rg5 derived from heat-processed ginseng have been shown to possess substantial anti-tumor-promoting effects. KG-135 is a formulated complex that contains several antitumorigenic ginsenosides, such as Rk1, Rg3, Rg5, Rk2, Rk3, Rs3, Rs4, Rs5, Rs6, Rs7, etc. The present article was aimed at evaluating the chemopreventive as well as anti-inflammatory effects of KG-135 in the human

Heme oxygenase-1 (HO-1) is a stress-responsive enzyme that has antioxidant and cytoprotective functions. However, HO-1 has oncogenic functions in cancerous or transformed cells. In the present work, we investigated the effects of HO-1 on the expression of p53 induced by 15-deoxy-Δ(12,14)-prostaglandin J2 (15d-PGJ2) in human breast cancer (MCF-7) cells. Treatment of MCF-7 cells with 15d-PGJ2 led to time-dependent increases in the expression of p53 as well as HO-1. Upregulation of p53 expression b

Background: The aim of this study was to explore the use of off-label/unlicensed drugs to confirm the safety and efficacy of their prescription in children in Korea. Methods: In this retrospective study, we analyzed data of patients who received any of the 32 drugs between January–December 2014 in tertiary hospitals in Korea, including demographics, diagnoses, reasons for the medication, administration route, and details of adverse drug reactions. Additionally, the mortality in the cohort was as

이 논문은 롤즈에 대한 샌델의 비판이 타당한가의 문제보다는 자유주의 정치철학에 맞서 샌델이 제시하는 공화주의적 대안이 과연 이론적정합성과 현실적 가능성을 지니는가를 밝히는 것을 목표로 한다. 샌델의공화주의의 핵심 주장은 다음과 같이 요약될 수 있다. 첫째, 공적 토론장에서 우리는 종교적, 도덕적 담론을 배제하지 말아야 한다. 둘째, 자기통치(self-rule)를 수행할 수 있는 시민적 덕을 육성하는 것이 가장 중요한 정치적 선이다. 셋째, 전지구적인(global) 시장주의를 막는 정치경제학이 필요하다. 넷째, 그 현실적인 대안은 주권의 분권화라는 다원주의이다. 이에 대해그 동안 제기되었거나 가능한 주요 반론들은 다음과 같다. 첫째, 샌델은도덕과 정치의 영역을 구분하지 못하고 통합주의적(integrationist) 가치를제시하는 반근대적 공동체주의자이다. 둘째, 샌델의 공화주의는 자유주의와차별화되지 않는다. 셋째, 주권의 분권화로 전지구적 시장주의를 막는 것은현실가능하지 않다. 넷째,

Three new sterols, 5a,8a-epidioxy-24-norcholesta-6,9(11),22-trien-3b-ol (1), 5a,8a-epidioxy-cholesta-6,9(11),24-trien-3b-ol (2), and 5a,8a-epidioxy-cholesta-6,23-dien-3b,25-diol (3), with four known sterols (4–7)were isolated from a marine sponge Monanchora sp. Theirchemical structures were elucidated by extensive spectroscopicanalysis. Compounds 1 and 3–7 showed moderatecytotoxicity against several human carcinoma cell linesincluding renal (A-498), pancreatic (PANC-1 and MIAPaCa-2), and colorec

A numerical study using nonlinear finite-element analysis is performed to investigate the behavior of reinforced-concrete flat plates subject to combined in-plane compressive and out-of-plane floor loads. For the nonlinear finite-element analysis, a computer program addressing material and geometric nonlinearities is developed. The flat plates to be studied are designed according to the direct design method. Through studies on the effects of different load combinations and loading sequence, the

Objective: To demonstrate the usefulness of 3-tesla (3T) magnetic resonance imaging (MRI) including T2-weighted imaging (T2WI), diffusion weighted imaging (DWI), time-of-flight (TOF) magnetic resonance angiography (MRA), T2*-weighted gradient recalled echo (GRE), and susceptibility weighted imaging (SWI) in diagnosing brain death. Materials and Methods: Magnetic resonance imaging findings for 10 patients with clinically verified brain death (group I) and seven patients with comatose or stuporous

An electron microbeam cell-irradiation (EMCI) system is now ready for routine operation in Korea. The system components include an electron gun operating at 1-100 keV, a beam transport chamber delivering a micron-sized beam, a cell image acquisition and positioning part and an automatic system control section. The present choice of source beam energy is 30 keV so that the radiation impact is conveyed to the targeted cells with a minimum spatial dispersion. The beam is available at 5 microm in di