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Mastoid and epitympanic obliteration is an effective option for preventing a retraction pocket and cholesteatoma recurrence in patients with a poorly functioning eustachian tube or a defective scutum, while preserving the same advantage of the canal wall up technique.

A peripheral origin is typically contemplated in a patient presenting with sudden hearing loss (HL) and dizziness without other neurologic manifestations. Although symptoms of anterior inferior cerebellar artery (AICA) infarction include sudden HL and vertigo, the clinical picture usually shows ipsilateral facial anesthesia or paralysis, Horner's syndrome, contralateral body anesthesia, or cerebellar dysmetria. A 68-year-old female patient developed sudden HL in the right ear and vertigo. A left

Sound frequency discrimination begins at the organ of Corti in mammals and the basilar papilla in birds. Both of these hearing organs are tonotopically organized such that sensory hair cells at the basal (proximal) end respond to high frequency sound, whereas their counterparts at the apex (distal) respond to low frequencies. Sonic hedgehog (Shh) secreted by the developing notochord and floor plate is required for cochlear formation in both species. In mice, the apical region of the developing c

The mammalian cochlear duct is tonotopically organized such that the basal cochlea is tuned to high frequency sounds and the apical cochlea to low frequency sounds. In an effort to understand how this tonotopic organization is established, we searched for genes that are differentially expressed along the tonotopic axis during neonatal development. Cochlear tissues dissected from P0 and P8 mice were divided into three equal pieces, representing the base, middle and apex, and gene expression profi

Adequate regulation of endolymphatic pH is essential for maintaining inner ear function. The Na(+)-H(+) exchanger (NHE) is a major determinant of intracellular pH (pH(i)), and facilitates Na(+) and fluid absorption in various epithelia. We determined the functional and molecular expression of NHEs in cultured human endolymphatic sac (ES) epithelial cells and examined the effect of IFN-gamma on NHE function. Serial cultures of human ES epithelial cells were generated from tissue samples. The mole

Cochlear implantation has become a relatively routine operation; however, like any surgical procedure, it carries a risk of complications. The likelihood of causing in_4 jury to adjacent vital structures is rare but can lead to serious consequences. During the surgical procedure, it is important to obtain maximal exposure through the facial recess to avoid potential risk to the carotid canal or the carotid artery. An intraoperative or postoperative radiograph should be obtained to confirm the co

The head impulse test paradigm (HIMP) assesses semicircular canal function by measuring compensatory saccades during head movements as an indication of an impaired vestibulo-ocular reflex (VOR). The recently introduced suppression head impulse test paradigm (SHIMP) examines anticompensatory saccades after head movements as a measure of intact VOR. Thus, HIMP measures a decrease in vestibular function, whereas SHIMP measures residual function. We evaluated the effectiveness of SHIMP, compared HIM

GA during forward walking was greater in dizzy patients under an EC condition than under an EO condition.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea Address correspondence and reprint requests to Eun Jin Son, M.D., Ph.D., Department of Otorhinolaryngology, Yonsei University College of Medicine, Gangnam Severance Hospital 712 Eonjuro, Gangnam-gu, Seoul, 135-720, Republic of Korea; E-mail: [email protected] The authors have no funding, financial relationships, or conflicts of interest to disclose.

Neuroendocrine tumors originating in the middle ear are rare, and presentation with facial paralysis is extremely uncommon. A 19-year-old woman with a history of transient facial paralysis presented with a right-sided middle ear mass. Surgical exploration of the tympanic cavity was performed using a transcanal endoscopic approach. Histopathologic examination confirmed the diagnosis of a middle ear neuroendocrine tumor. After surgical excision of the tumor, no recurrence or facial paralysis occur

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