이규리 교수
Gyuri Lee
고려대학교 바이오시스템의과학부 · 농업·생명과학
연구실 소개
이규리 교수의 연구실은 주로 식품 및 환경에서 오염된 독성 물질, 특히 아프리코신과 옥탈록신과 같은 균류 독소의 생물학적 분해를 위한 미생물 및 효소의 활용을 핵심 연구 분야로 삼고 있습니다. 또한, 발효식품인 콤부차의 미생물 군집과 대사 변화를 분석하며, 식품 안전성 향상에 기여할 수 있는 유용한 미생물의 도입을 연구하고 있습니다. 최근에는 피부 노화 방지 기능을 가진 프로바이오틱스와 프리바이오틱스의 기전 연구를 통해 건강 기능 식품 및 기능성 소재 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15isolates and their enzymes have the potential for practical application to reduce levels of OTA in food and feed.
Kombucha is a fermented beverage containing organic acids by yeast and acetic acid bacteria. In this study, microbial community analysis of kombucha produced in Korea was performed, and changes in components during kombucha fermentation were analyzed using commercial kombucha pellicle and culture broth as starter. The major phylum-level strains of commercial kom-1 and kom-2 showed differences in proteobacteria of 35.60% and 78.1%, and Firmicutes of 64.06% and 15.57%, respectively. During ferment
Aflatoxins are classified as Group 1 (carcinogenic to humans) by the International Agency for Research on Cancer. In this study, a total of 134 fungal strains were isolated from 65 meju samples, and two fungal isolates were selected as potential aflatoxin B<sub>1</sub> (AFB<sub>1</sub>)-biodetoxification fungi. These fungi were identified as <i>Aspergillus oryzae</i> MAO103 and <i>A. oryzae</i> MAO104 by sequencing the beta-tubulin gene. The two <i>A. oryzae</i> strains were able to degrade more
Overexposure to ultraviolet B (UVB) irradiation induces photoaging that is characterized by the formation of wrinkles and loss of skin elasticity. To understand the mechanism of action of probiotics and prebiotics in skin protection against photoaging, we investigated the effects of dietary supplementation with the probiotic, <i>Bifidobacterium longum</i>, and prebiotic, galacto-oligosaccharide, on UVB-induced photoaging in hairless mice. We measured short chain fatty acid (SCFA) levels, antioxi
INTRODUCTION: Facemasks are an important piece of personal protective equipment (PPE) to mitigate the spread of respiratory illnesses, but they can impede communication between patients and healthcare providers. The purpose of this scoping review is to identify effective communication practices while wearing facemasks. DESIGN: Scoping review using a systematic search of articles from the PubMed, CINAHL, and Embase databases. METHODS: The PEO (population, exposure, outcome) methodology was select
Abstract Person-centered mealtime care is individually tailored and directly delivered care that engages individuals in mealtime activities and addresses their needs and preferences. Person-centered mealtime care is associated with positive mealtime behaviors and outcomes in older adults with dementia. Existing tools that assess caregiver knowledge and self-efficacy of mealtime care have low psychometric quality, and few tools focus on person-centered mealtime care. This study developed and test
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