최규선 교수
Gyusun Choi
한양대학교 신경외과 · 의학
연구실 소개
최규선 교수의 연구실은 뇌출혈, 뇌경련, 심정지 등 신경외과적 급성 뇌질환의 예후 및 위험도 평가를 중심으로 연구를 진행하고 있습니다. 특히 출혈성 뇌졸중과 뇌출혈 환자의 장기적 기능적 결과에 영향을 미치는 뇌위축, 생체마커(copeptin) 등 다양한 예측 인자를 규명하고 있으며, 치료 전략의 근거를 마련하기 위한 메타분석과 임상 연구를 융합적으로 수행하고 있습니다. 특히 항경련제 사용의 적정성과 장기적 합병증에 대한 분석을 통해 임상적 실무에 기여하고자 합니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Perioperative seizures are not significant predictors for late epilepsy. Instead, initial amount of SAH and surgery-induced cortical damage should be seriously considered as risk factors for late epilepsy. Because AEDs can not prevent early postoperative seizures (< 1 week) and potentially cause unexpected side effects, long-term use should be readjusted in high-risk patients.
We performed a meta-analysis to compare the impact of extracorporeal cardiopulmonary resuscitation (ECPR) to that of conventional cardiopulmonary resuscitation (CCPR) in adult patients who experience cardiac arrest of cardiac origin. A literature search was performed using criteria set forth in a predefined protocol. Report inclusion criteria were that ECPR was compared to CCPR in adult patients with cardiac arrest of cardiac origin, and that survival and neurological outcome data were available
This study aimed to evaluate the effect of brain atrophy on the functional outcome of patients with moderate-volume basal ganglia hemorrhage. Of 1003 patients with spontaneous intracerebral hemorrhage, 124 with moderate-volume basal ganglia hemorrhage (hematoma volume of 20-50 mL) were enrolled. The intercaudate distance (ICD) and sylvian fissure ratio (SFR) were used as linear brain atrophy parameters. The patients were divided into groups with favorable and unfavorable outcomes, according to t
Objective : Although prophylactic antiepileptic drug (AED) use in patients with aneurysmal subarachnoid hemorrhage (SAH) is a common practice, lack of uniform definitions and guidelines for seizures and AEDs rendered this prescription more habitual instead of evidence-based manner. We herein evaluated the incidence and predictive factors of seizure and complications about AED use. Methods : From July 1999 to June 2007, data of a total of 547 patients with aneurysmal SAH who underwent operative t
Copeptin, the C-terminal part of provasopressin, has emerged as a novel prognostic marker after hemorrhagic or ischemic stroke. The aim of this study was to quantitatively assess the prognostic significance of plasma copeptin level on functional outcome and mortality in patients with acute stroke using a meta-analysis of the available evidence. Thirteen relevant studies from 2,746 patients were finally included in our study. An elevated plasma copeptin level was associated with an increased risk
Introduction: The transcranial approach (TCA) has historically been used to remove craniopharyngiomas. Although the extended endoscopic endonasal approach (EEA) to these tumors has been more commonly accepted in the recent two decades, there is debate over whether this approach leads to better outcomes. The goal of this systematic review and meta-analysis was to more comprehensively understand the benefits and limitations of these two approaches in craniopharyngioma resection based on comparativ
Reconstruction of patient-specific scaffolds to repair uniquely shaped bone defects remains a major clinical challenge in tissue engineering. Recently, three-dimensional (3D) printed scaffolds have received considerable attention as a promising technology for the rapid generation of custom shapes. However, synthetic polymers commonly used for 3D printing, such as polycaprolactone (PCL), lack the biological capacity to mimic native extracellular matrix functions to support cell growth and differe
cular diseases. She was in normotensive and in sinus rhythm. A computed tomography (CT) scan revealed SAH on left basal cistern (Fig. Magnetic resonance (MR) images showed an acute ischemic lesion in the territory of the left middle cerebral artery with restricted diffusion (Fig. Digital subtraction angiography (DSA) demonstrated an irregularly shaped aneurysm arising from left supraclinoid ICA with moderate stenosis of proximal region (Fig. Moreover, DSA revealed one of the typical findings of
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