이해정 교수

Abstract Background Bacterial isolates with multiple plasmids harbouring different carbapenemase genes have emerged and been identified repeatedly, despite a general notion that plasmids confer fitness cost in bacterial host. In this study, we investigated the effects of plasmids with carbapenemase genes on the fitness and virulence of bacteria. Methods Different plasmids harbouring the carbapenemase genes, bla NDM-1 and bla OXA-232 , were isolated from a carbapenem-resistant K. pneumoniae strai

PURPOSE: This study was to determine the mediator or moderator role of social support in the relationship between stress and depression among family caregivers of older adults with dementia. METHOD: Sixty nine family caregivers were randomly selected from health care centers in P city and a face-to-face interview was conducted using questionnaires from January to May of 2002. Data were analyzed with descriptive statistics, Pearson correlation, and hierarchical multiple regression using SPSS prog

Nine Klebsiella pneumoniae isolates coproducing NDM-1 and OXA-232 carbapenemases were successively isolated from a single patient. Although they were isolated simultaneously and were isogenic, they presented different colony phenotypes (matt and mucoid). All nine isolates were resistant to most antibiotics except colistin and fosfomycin. In addition, matt-type isolates were resistant to tigecycline. No differences were detected in the cps cluster sequences, except for the insertion of IS5 in the

PURPOSE: The purpose of this study was to explore the levels of depression experienced by clients (N=152) with Type 2 Diabetes Mellitus(DM), and to compare the levels of self care activity, metabolic control and cardiovascular risk factors between depressed and non-depressed clients. METHOD: Participants aged 50 and above were conveniently recruited in B city. The levels of depression, self-care activity, metabolic control of glucose and lipids, and cardiovascular risk factors of the participant

PURPOSE: The purpose of the study was to identify the effects of problem solving nursing counseling and intensified walking exercise on diabetic self-care, coping strategies, and glycemic control among older adults with DM type II. METHOD: Ninety nine DM patients who were older than 50 were recruited from DM clinics or public health centers and conveniently assigned into three groups: the Polar (n=41), counseling (n=30) and control groups (n=28). Participants in both Polar and counseling groups

OBJECTIVES: Bacteria that acquire plasmids incur a biological cost. Despite this fact, clinical Enterobacteriaceae isolates commonly contain multiple co-existing plasmids harbouring carbapenemase genes. METHODS: Six different plasmids carrying blaNDM-1, blaNDM-5, blaCTX-M-15, blaKPC-2, blaOXA-181 and blaOXA-232 genes were obtained from Klebsiella pneumoniae and Escherichia coli clinical isolates. Using the E. coli DH5α strain as recipient, 14 transconjugants with diverse plasmid combinations (si

Employing an electron-beam (E-beam) cured hydrogen silsesquioxane (HSQ) based inorganic spin-on-glass as a pre-metal dielectric (PMD) material, we developed a simple planarization process with low thermal budget and good planarity in stacked capacitor dynamic random access memory (STC DRAM) device. We observe the basic E-beam cured HSQ film characteristics such as Fourier-transform infrared absorption spectra (FTIR), wet etch rate, film shrinkage, refractive index (RI), X-ray photoelectron spect

Objectives: Adolescents frequently skip breakfast for a variety of reasons. We investigated associations between lifestyle, emotional state, and breakfast consumption in adolescents. Methods: Data from 62276 adolescents were derived from the 13th Korean Youth Risk Behavior Web-based Survey (KYRBS), conducting from June 1, 2017 to June 30. The adolescents were drawn by stratified multistage clustered samples from 400 middle schools and 400 high schools. Breakfast skipper was defined as those who

The relatively low levels of amylin, compared to those in overweight controls, during the early phase of glucose loading in patients with PWS, may contribute, in part, to the excessive appetite of PWS patients as compared to the overweight controls.

Although a small number of patients were studied, self-bougienage was safe, less invasive, and effective for the management of esophageal restenosis in patients who required frequent dilation after surgery.

The present study showed that socioeconomic status might not an important risk factor for obesity in Korean children. These results warrant further studies to clarify the association between SES and obesity in Korean children.

The purpose of this study was to examine the levels of depression experienced by Korean hospital nurses (N=198) and to identify discriminating factors of their depression experience among personal and environmental characteristics. Method: A cross-sectional survey design was used to answer the resea...