박혜진 교수

AIM: To evaluate local control and patient survival for recurrent or oligometastatic uterine cervical cancer treated with stereotactic body radiotherapy (SBRT) using CyberKnife, and to demonstrate the safety of SBRT. PATIENTS AND METHODS: Between 2002 and 2013, 100 recurrent or oligometastatic lesions in 85 patients were treated with SBRT at three Institutions. SBRT sites were within the previous RT field in 59 and partially overlapped in nine. SBRT sites included three local recurrences, 89 lym

PURPOSE: In a recent meta-analysis, post-mastectomy radiotherapy (PMRT) reduced any first recurrence (AFR) and improved survival in N1 and N2 patients. We investigated risk factors for AFR in N1 after optimal systemic therapy without PMRT, to define a subgroup of patients who may benefit from PMRT. MATERIALS AND METHODS: One thousand three hundred eighty-two pT1-2N1M0 breast cancer patients treated with mastectomy without PMRT between 2005 and 2010 were retrospectively analyzed. Only 0.6% had no

Functional imaging modalities enable practitioners to identify functional lung regions. This analysis evaluated the feasibility of nuclear medicine imaging to avoid doses to the functional lung in radiotherapy (RT) planning for patients with lung cancer. This systematic review and meta-analysis was carried out according to PRISMA-P guidelines. A search of EMBASE and PubMed for studies published throughout the last 20 years was performed using the following search criteria: (a) 'lung cancer' or '

The purpose of this study was to evaluate local control and survival in patients with spinal metastases who were treated with stereotactic body radiotherapy (SBRT) using a CyberKnife, with or without a prior history of irradiation, and to identify prognostic factors predicting them. Between August 2008 and November 2012, 59 spinal metastatic lesions in 39 patients were treated with SBRT. Fourteen lesions (23.7%) were re-irradiated to treat recurrence after prior radiotherapy. Patients were treat

Adjuvant radiotherapy (RT) is a well-established treatment for breast cancer. However, there is a large degree of variation and controversy in practice patterns. A nationwide survey on the patterns of practice in breast RT was designed by the Division for Breast Cancer of the Korean Radiation Oncology Group. All board-certified members of the Korean Society for Radiation Oncology were sent a questionnaire comprising 39 questions on six domains: hypofractionated whole breast RT, accelerated parti

MPTB patients undergoing surgery with or without adjuvant RT had a favorable outcome. Although there was no local recurrence in patients treated with adjuvant RT, the effect of adjuvant RT failed to reach a statistical significance. Risk-grouping based on pathological features might help design a clinical trial for MPTB.

BACKGROUND: To evaluate the prognostic value of neutrophil-lymphocyte ratio (NLR) in rectal cancer patients treated with preoperative chemoradiotherapy (CRT) and curative surgery. METHODS: A comprehensive search of the EMBASE and PubMed databases was performed to screen studies that compared treatment outcomes according to the pre-CRT and/or post-CRT NLR in patients receiving preoperative CRT and curative surgery for locally advanced rectal cancer. Hazard ratios (HRs) for disease-free survival (

BACKGROUND: To analyze treatment outcomes and patterns of recurrence, and to examine the impact of adjuvant postoperative radiotherapy (PORT) after esophagectomy in esophageal squamous cell carcinoma (SqCC) regarding the status of circumferential resection margin (CRM). PATIENTS AND METHODS: We performed a retrospective review of esophageal cancer patients operated in Seoul National University Hospital between 2003 and 2010. Pathologically proven T3 SqCC patients with written reports mentioning

PURPOSE: To evaluate the impact of postoperative radiotherapy (PORT) on patterns of failure and survivals in uterine carcinosarcoma patients treated with radical surgery. MATERIALS AND METHODS: Between October 1998 and August 2010, 19 patients with stage I-III uterine carcinosarcoma received curative hysterectomy and bilateral salpingo-oophorectomy with or without PORT at Seoul National University Hospital. Their hospital medical records were retrospectively reviewed. PORT and non-PORT groups in

The adoption of HypoFx RT after BCS for invasive breast cancer and DCIS has increased significantly, whereas the use of HypoFx PMRT has increased moderately since 2017. However, further studies are required to determine the optimal use of RNI.

대상판결은 의사결정능력이 있는 미성년자인 환자에 대한 의사의 설명의무를 처음으로 다룬 대법원 판결일 뿐만 아니라 어떠한 경우에 의사가 의사결정능력이 있는 미성년자 환자에게 ‘직접’ 설명할 의무를 부담하는지에 대한 판단 기준을 제시하였다는 점에서 중요한 의미가 있다. 대상판결은 우선, 의사는 의사결정능력이 있는 미성년자인 환자에 대해서 의료행위에 관하여 설명할 의무를 부담한다고 선언하였다. 다만, 이때 설명의무는 원칙적으로 ‘간접적’ 설명, 즉 친권자 또는 법정대리인에게 설명하여 그 설명이 미성년자에게 전달되도록 하는 방식으로 이행할 수 있고, 예외적으로 미성년자인 환자에게 직접 의료행위에 관하여 설명하고 승낙을 받을 필요가 있는 ‘특별한 사정’이 있으면 미성년자인 환자에게 ‘직접’ 설명하는 방식으로 이행하여야 한다고 한다. 결국, (1) 미성년자가 의사결정능력이 있고, (2) 직접 설명하여야 하는 특별한 사정이 인정되는 두 단계의 요건이 충족되는 경우에만 의사가 미성년자 환자에게 ‘

FB-VMAT can deliver radiation doses safely without adversely affecting the liver. The mean dose ≤4 Gy could be a useful dose criterium of the liver for FB-VMAT plans.