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심행선 교수

Haeseon Sim

성균관대학교 의학과 · 의학

연구실 소개

심행선 교수의 연구실은 신장 손상, 심혈관계 질환, 청력 손실 등 중증 질환의 위험 요인과 예후를 분석하는 데 초점을 맞추고 있습니다. 특히 간 이식 후 급성 신손상(AKI)의 예측 모델 개발과 대사증후군이 청력 손실에 미치는 영향에 대한 기전 연구를 중심으로 진행되고 있습니다. 또한 약물 중독 치료를 위한 지질 에멀전의 혈역학적 효과와 신경조절 작용에 대한 기초 연구도 함께 수행하고 있습니다.

급성 신손상대사증후군청력 손실약물 중독 치료혈역학 기전

연구 현황

논문 수
39
총 인용 수
469
최근 5년 논문
9
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
9총합
2017
2018
2019
2022
2023
5개년 연도별 피인용 수
120총합
20172018201920222023

주요 논문

15
1
논문|인용수 93·2015
Clinical Risk Scoring Models for Prediction of Acute Kidney Injury after Living Donor Liver Transplantation: A Retrospective Observational Study
Mi Hye Park, Haeng Seon Shim, Won Ho Kim, HyoJin Kim, Dong Joon Kim, Seong-Ho Lee, Chung Su Kim, Mi Sook Gwak, Gaab Soo Kim
SJR Q1PLoS ONEOA

Acute kidney injury (AKI) is a frequent complication of liver transplantation and is associated with increased mortality. We identified the incidence and modifiable risk factors for AKI after living-donor liver transplantation (LDLT) and constructed risk scoring models for AKI prediction. We retrospectively reviewed 538 cases of LDLT. Multivariate logistic regression analysis was used to evaluate risk factors for the prediction of AKI as defined by the RIFLE criteria (RIFLE = risk, injury, failu

HepatologyMedicine
2
논문|인용수 77·2018
Association of Metabolic Syndrome With Sudden Sensorineural Hearing Loss
Su Young Jung, Haeng Seon Shim, Young Min Hah, Sang Hoon Kim, Seung Geun Yeo
SJR Q1JAMA Otolaryngology–Head & Neck SurgeryOA

The rate of recovery from SSNHL was lower among patients with metabolic syndrome than among those without metabolic syndrome, and prognosis was poorer in patients with 4 or more diagnostic factors of the metabolic syndrome.

NeurologyNeuroscience
3
논문|인용수 67·2016
The effects of uterine artery embolization on ovarian reserve
Chang-Woon Kim, Haeng Seon Shim, Hong Jang, Yun Gyu Song
SJR Q2European Journal of Obstetrics & Gynecology and Reproductive BiologyOA
Obstetrics and GynecologyMedicine
4
논문|인용수 66·2015
Potentially Modifiable Risk Factors For Acute Kidney Injury After Surgery on The Thoracic Aorta
Won Ho Kim, Mi Hye Park, Hyo Jin Kim, Hyunyoung Lim, Haeng Seon Shim, Ju‐Tae Sohn, Chung Su Kim, Sangmin Maria Lee
SJR Q3MedicineOA

Perioperative risk factors were identified for acute kidney injury (AKI) defined by the RIFLE criteria (RIFLE = risk, injury, failure, loss, end stage) after surgery on the thoracic aorta with cardiopulmonary bypass (CPB) in this case-control study. A retrospective review was completed for 702 patients who underwent surgery on the thoracic aorta with CPB. A total of 183 patients with AKI were matched 1:1 with patients without AKI by a propensity score. Matched variables included age, gender, bod

NephrologyMedicine
5
논문|인용수 37·2014
Systemic Blockage of Nitric Oxide Synthase by L-NAME Increases Left Ventricular Systolic Pressure, Which Is Not Augmented Further by Intralipid®
Il-Woo Shin, Young‐Sool Hah, Cheol Kim, Jung‐Chul Park, Hee-Won Shin, Kyeong-Eon Park, Seong‐Ho Ok, Heon-Keun Lee, Young-Kyun Chung, Haeng Seon Shim, Dong Hoon Lim, Ju‐Tae Sohn
SJR Q1International Journal of Biological SciencesOA

Intravenous lipid emulsions (LEs) are effective in the treatment of toxicity associated with various drugs such as local anesthetics and other lipid soluble agents. The goals of this study were to examine the effect of LE on left ventricular hemodynamic variables and systemic blood pressure in an in vivo rat model, and to determine the associated cellular mechanism with a particular focus on nitric oxide. Two LEs (Intralipid(®) 20% and Lipofundin(®) MCT/LCT 20%) or normal saline were administere

Pathology and Forensic MedicineMedicine
6
논문|인용수 23·2011
Protein kinases participate in the contraction in response to levobupivacaine in the rat aorta
Haeng Seon Shim, Seong‐Ho Ok, Soo Hee Lee, Seong‐Chun Kwon, Ju‐Tae Sohn
SJR Q1European Journal of Pharmacology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
논문|인용수 22·2012
Dexmedetomidine-induced contraction of isolated rat aorta is dependent on extracellular calcium concentration
Seong‐Ho Ok, Sung Il Bae, Haeng Seon Shim, Ju‐Tae Sohn
SJR Q1Korean journal of anesthesiologyOA

Taken together, these results suggest that dexmedetomidine-induced contraction is primarily dependent on extracellular calcium concentrations that contribute to calcium influx via voltage-operated calcium channels of isolated rat aortic smooth muscle. Dexmedetomidine-induced contraction is mediated by α(2)-adrenoceptor stimulation. Dexmedetomidine-induced contraction appears to be partially mediated by calcium release from the sarcoplasmic reticulum.

Anesthesiology and Pain MedicineMedicine
8
논문|인용수 18·2016
Predictive Value of Intraoperative Thromboelastometry for the Risk of Perioperative Excessive Blood Loss in Infants and Children Undergoing Congenital Cardiac Surgery: A Retrospective Analysis
Eun‐Hee Kim, Haeng Seon Shim, Won Ho Kim, Sue-Young Lee, Sun-Kyung Park, Ji-Hyuk Yang, Tae-Gook Jun, Chung Su Kim
SJR Q2Journal of Cardiothoracic and Vascular Anesthesia
Critical Care and Intensive Care MedicineMedicine
9
논문|인용수 15·2019
Metabolic syndrome is associated with hearing disturbance
Haeng Seon Shim, Hye Jin Shin, Myung Gu Kim, Joon Soo Kim, Su Young Jung, Sang Hoon Kim, Seung Geun Yeo
SJR Q2Acta Oto-Laryngologica

MetS may be associated with hearing loss, especially in subjects who meet four or five of the diagnostic criteria for MetS.

Cardiology and Cardiovascular MedicineMedicine
10
논문|인용수 8·2017
Comparative Analysis of the Combined Therapeutic Effects of Lipoprostaglandin E1 on Sudden Idiopathic Sensorineural Hearing Loss
Haeng Seon Shim, Joon Soo Kim, Myung Gu Kim
SJR Q2Journal of Audiology & OtologyOA

The study results suggested that the CP group received effective treatment modalities for ISSNHL. The combined therapy of lipo-PGE<sub>1</sub> with carbogen inhalation in patients with ISSNHL was more beneficial than other treatment modalities.

NeurologyNeuroscience
11
논문|인용수 3·2008
Anesthetic Management of a Patient with Complete Tracheal Transection by Blunt Trauma - A case report -
Haeng Seon Shim, Min Hyoun Noe, In Kyu Kim, Myoung Keun Shin, Seong Ho Lee
SJR Q1Korean Journal of Anesthesiology

Tracheobronchial rupture due to blunt chest trauma is an uncommon injury and the clinical presentations are variable.Recently, the incidence of tracheobronchial injuries has increased with the increase in traffic accidents and mechanization.The early diagnosis and primary repair of tracheobronchial rupture not only restores normal lung function, but also avoids the difficulties and complications associated with delayed diagnosis and repair.We report our clinical experience in anesthetic manageme

SurgeryMedicine
12
논문|인용수 3·2005
Pneumothorax during Retroperitoneal Laparoscopic Nephrectomy: A case report
Haeng Seon Shim, Soon Hee Park, Do Hyun Ryu, In Kyu Kim, Myoung Keun Shin
SJR Q1Korean Journal of AnesthesiologyOA

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Pulmonary and Respiratory MedicineMedicine
13
논문|인용수 1·2007
진단되지 않은 계류 척수 증후군 환자의 척추마취와 관련된 신경학적 후유증
심행선, 이성호, 박현식, 김인규, 신명근, 김재호

Tethered cord syndrome is a form of spinal dysraphism, with a low-lying conus frequently associated with an intraspinal lipoma, diastematomyelia or fibrous band. The clinical manifestations include spine abnormalities, such as spina bifida, or various neurological symptoms involving the lower extremities and sphincters. Herein, our experience of a 42-year-old female tethered cord syndrome patient, with deficit, paresthesia and incontinence following spinal anesthesia for anti-incontinence surger

14
논문|인용수 1·2005
Intubating Conditions and Hemodynamic Changes during Tracheal Intubation with Propofol Followed by Remifentanil without the Use of Muscle Relaxant
Haeng Seon Shim, Tae‐Sik Park, Soon Hee Park, Seong Ho Lee, In Kyu Kim, Myoung Keun Shin
SJR Q1Korean Journal of AnesthesiologyOA

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Anesthesiology and Pain MedicineMedicine
15
논문|인용수 1·2009
체위 변화에 따른 복강경 수술의 혈역학적 변화의 비교
심행선, 신명근, 성우성, 김인규, 이성호

Background: The authors evaluated the hemodynamic effects of body position measured by esophageal Doppler monitor (EDM) during laparoscopic cholecystectomy or gynecologic laparoscopic surgery. Methods: Fifty patients scheduled to undergo laparoscopic cholecystectomy (Group C) or gynecologic laparoscopic surgery (Group G), were divided into two groups. Pneumoperitoneum was instituted by CO2 gas and the intraperitoneal pressure was kept under 12 mmHg. Hemodynamic parameters at critical points were

대표 연구 분야

Anesthesiology and Pain MedicineSurgeryCardiology and Cardiovascular MedicineNeurologyPulmonary and Respiratory MedicineHepatology

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