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김하은 교수

Haeun Kim

연세대학교 흉부외과 · 의학

연구실 소개

김하은 교수의 연구실은 생체 고분자, 특히 점액질인 소부maxillary 점액단백질(Bovine Submaxillary Mucin, BSM)의 O-당화 구조와 그 기능적 역할을 분석하는 데 초점을 맞추고 있습니다. 특히 액체 크로마토그래피-질량분석법을 활용한 정량적 및 구조적 분석을 통해 당화의 다양성과 관련된 분자 메커니즘을 규명하고 있습니다. 이와 더불어 심혈관계 및 호흡기계 질환에서의 생체 반응, 특히 ECMO를 통한 심부전 환자에서의 심장 및 폐 기능 저하에 대한 기전과 치료 전략에 대해서도 연구를 진행하고 있습니다. 최근에는 전염병 기간 동안 소비자 행동과 온라인 경험의 심리적 반응을 시간적 프레임이 어떻게 영향을 주는지에 대한 소비자 심리학적 연구도 포함하고 있습니다.

점액단백질O-당화ECMO심부전소비자 심리

연구 현황

논문 수
132
총 인용 수
768
최근 5년 논문
70
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
70총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
238총합
20222023202420252026

주요 논문

15
1
논문|인용수 30·2020
Structural and Quantitative Characterization of Mucin-Type O-Glycans and the Identification of O-Glycosylation Sites in Bovine Submaxillary Mucin
Jihye Kim, Changsoo Ryu, Jongkwan Ha, Junmyoung Lee, Donghwi Kim, Minkyoo Ji, Chi Soo Park, Jaeryong Lee, Dae Jung Kim, Ha Eun Kim
SJR Q1BiomoleculesOA

Bovine submaxillary mucin (BSM) is a gel-forming glycoprotein polymer, and Ser/Thr-linked glycans (O-glycans) are important in regulating BSM’s viscoelasticity and polymerization. However, details of O-glycosylation have not been reported. This study investigates the structural and quantitative characteristics of O-glycans and identifies O-glycosylation sites in BSM using liquid chromatography–tandem mass spectrometry. The O-glycans (consisting of di- to octa-saccharides) and their quantities (%

Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
논문|인용수 19·2021
Prognostic effect of perineural invasion in surgically treated esophageal squamous cell carcinoma
Ha Eun Kim, Sung Yong Park, Hyunki Kim, Dae Joon Kim, Sun Il Kim
SJR Q2Thoracic CancerOA

BACKGROUND: Although perineural invasion is a well known prognostic factor used in several cancers, its prognostic role in esophageal squamous cell carcinoma remains controversial. Here, we investigated the prognostic role of perineural invasion in surgically treated esophageal squamous cell carcinoma. METHODS: We retrospectively reviewed the medical records of 316 patients who underwent esophagectomy and lymph node dissection for esophageal squamous cell carcinoma between 2007 and 2016. RESULTS

SurgeryMedicine
3
논문|인용수 17·2024
Fabrication and evaluation of chitosan-coated nanostructured lipid carriers for co-delivery of paclitaxel and PD-L1 siRNA
Ha Eun Kim, Young‐Guk Na, Minki Jin, Bomin Song, Taek-Seon Yun, Yu-Rim Hwang, Jeong‐Sook Park, Jae-Young Lee, Jong-Suep Baek, Su-Cheol Han, Hong-Ki Lee, Cheong‐Weon Cho
SJR Q1International Journal of Pharmaceutics
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
논문|인용수 14·2016
Left Atrial Decompression by Percutaneous Left Atrial Venting Cannula Insertion during Venoarterial Extracorporeal Membrane Oxygenation Support
Ha Eun Kim, Jo Won Jung, Yu Rim Shin, Han Ki Park, Young Hwan Park, Hong Ju Shin
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

Patients with venoarterial extracorporeal membrane oxygenation (ECMO) frequently suffer from pulmonary edema due to left ventricular dysfunction that accompanies left heart dilatation, which is caused by left atrial hypertension. The problem can be resolved by left atrium (LA) decompression. We performed a successful percutaneous LA decompression with an atrial septostomy and placement of an LA venting cannula in a 38-month-old child treated with venoarterial ECMO for acute myocarditis.

Biomedical EngineeringEngineering
5
논문|인용수 12·2021
Basiliximab Induction with Delayed Calcineurin Inhibitors for High-Risk Lung Transplant Candidates
Ha Eun Kim, Hyo Chae Paik, Su Jin Jeong, Moo Suk Park, Song Yee Kim, Jin Gu Lee
SJR Q2Yonsei Medical JournalOA

Basiliximab induction with delayed CNI initiation for high-risk patients might decrease the incidence of perioperative complications, including acute renal failure, without increasing the risk of acute rejection.

SurgeryMedicine
6
논문|인용수 12·2021
COVID-19 Uncertainty and Temporal Framing in Advertising for Online Experiential Consumption
Ha Eun Kim, Yoon‐Na Cho, Nara Youn
SJR Q1Journal of Advertising

During the period of uncertainty and lack of control caused by the COVID-19 pandemic, we investigated how consumers evaluate online experiences using messages framed in different temporal perspectives. In the midst of the coronavirus outbreak, companies have been offering their experiential services online either in single long sessions (i.e., proximal framed message) or multiple short sessions over time (i.e., distal framed message). We found significant two-way interactions between temporal fr

Applied PsychologyPsychology
7
논문|인용수 10·2024
Confirmation of the feasibility of using agrobyproduct biochar in thermal power plants through oxygen pyrolysis and conventional pyrolysis
Sunyong Park, Seok Jun Kim, Kwang Cheol Oh, Kwang Cheol Oh, Seon Yeop Kim, Ha Eun Kim, Jae Youl Shin, Dae-Hyun Kim, Ha Eun Kim, Jae Youl Shin, Dae-Hyun Kim
SJR Q1Journal of Analytical and Applied Pyrolysis
Biomedical EngineeringEngineering
8
논문|인용수 9·2021
Risk factors for pulmonary complications after neoadjuvant chemoradiotherapy followed by surgery for non‐small cell lung cancer
Ha Eun Kim, Woo Sik Yu, Chang Young Lee, Jin Gu Lee, Dae Joon Kim, Sung Yong Park
SJR Q2Thoracic CancerOA

BACKGROUND: We aimed to investigate the characteristics and pretreatment risk factors for postoperative pulmonary complications (PPCs) after neoadjuvant concurrent chemoradiotherapy (CRTx) in patients with non-small cell lung cancer (NSCLC). METHODS: We retrospectively reviewed data of 122 patients who underwent curative resection after neoadjuvant CRTx for NSCLC between 2007 and December 2019. Clinical data, including pulmonary function and body mass index (BMI) at the time of concurrent CRTx i

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 9·2014
Combined Orbital Floor Wedge Implant and Fornix Reconstruction for Postenucleation Sunken Socket Syndrome
Ha Eun Kim, Sun Young Jang, Jin Sook Yoon
SJR Q1Plastic & Reconstructive SurgeryOA

Therapeutic, IV.

GeneticsBiochemistry, Genetics and Molecular Biology
10
논문|인용수 8·2018
Preoperative Corticosteroid Use and Early Postoperative Bronchial Anastomotic Complications after Lung Transplantation
Ha Eun Kim, Hyo Chae Paik, Song Yee Kim, Moo Suk Park, Jin Gu Lee
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

BACKGROUND: Airway anastomotic complications are a leading cause of mortality after lung transplantation. Among the factors that cause airway complications, preoperative steroid use has been considered to be related with postoperative airway healing. We analyzed the influence of preoperative steroid use on postoperative airway complications. METHODS: The medical records of 66 double-lung transplant recipients from January 2014 to December 2015 were reviewed. Forty patients were prescribed steroi

SurgeryMedicine
11
논문|인용수 7·2021
The Effect of Academic Self-Efficacy, Perceived Usefulness, Perceived Ease of Use, and Acceptance Attitude on Learning Persistence through Student Engagement in MOOC
Ha Eun Kim, Hae‐Deok Song, Ye-chan Lee
EdMedia + Innovate Learning
Information SystemsComputer Science
12
논문|인용수 7·2018
Antioxidant Activities of Brussels Sprouts Powder and Its Application to Pork Patties on the Physicochemical Properties and Antioxidant Activity during Refrigerated Storage
Ha Eun Kim, Koo Bok Chin
SJR Q3Journal of the Korean Society of Food Science and Nutrition

본 연구는 방울양배추를 80% 에탄올 추출물과 에탄올, 물 추출물을 통한 항산화 활성을 평가하고 이를 첨가한 돈육패티의 이화학적 특성 및 항산화 활성을 평가하기 위해 실시되었다. 방울양배추의 세 가지 추출물의 총 페놀성 화합물 함량은 물과 80% 에탄올 추출물이 각각 2.86 g/100 g, 3.23 g/100 g으로 두 추출물 모두 유의적 차이를 보이지 않았으나 에탄올 추출물 1.35 g/100 g보다 유의적으로 높았다(P<0.05). DPPH 라디칼 소거능에서는 0.1%에서 방울양배추 80% 에탄올 추출물이 대조구 다음으로 높은 소거능을 보였다. 0.25% 이상부터는 방울양배추 에탄올 추출물이 대조구 다음으로 높은 소거능을 보였다(P<0.05). 철 이온 흡착력은 0.5%의 농도까지는 방울양배추의 물 추출물과 80% 에탄올 추출물이 대조구인 EDTA 다음으로 높은 흡착력을 보였다. 1%에서는 이 두 처리구와 대조구에서 유의적 차이를 보이지 않았다(P>0.05). 환원력은 대조구인

Food ScienceAgricultural and Biological Sciences
13
논문|인용수 6·2024
Predictive modelling of lignocellulosic biomass fuel changes during torrefaction via mass reduction
Sunyong Park, Seok Jun Kim, Kwang Cheol Oh, Seon Yeop Kim, Ha Eun Kim, Dae‐Hyun Kim, Ha Eun Kim, Ha Eun Kim, Dae‐Hyun Kim
SJR Q1Journal of the Energy Institute
Biomedical EngineeringEngineering
14
논문|인용수 5·2022
The Development of Using the Postpositional Morpheme “Bojosa” in Spontaneous Language Sample of 2-4 Year of Age
Ha Eun Kim, So-Jung Oh, YoonKyoung Lee
Journal of speech-language & hearing disorders

목적 : 본 연구는 자발화에서 보조사의 사용 빈도와 유형수를 측정하여 영유아기 보조사 사용 양상을 살펴보고자 하였다.BR방법 : 총 60명의 영유아(2세 후반, 3세 후반, 4세 후반의 세 연령집단별 각 20명씩)가 발화표본 수집에 참여하였다. 연구자와 책과 그림을 보며 대화하는 상황에서 아동 별로 50개 발화를 수집하여 H-SAK 프로그램을 사용해 형태소 단위로 분석하였고, 보조사의 사용은 보조사 전체 사용 빈도와 전체 유형수, 보조사 하위기능별 사용 빈도 및 유형수를 측정하였다. 이에 더해 보조사 하위유형별 사용 비율을 측정하였다.BR결과 : 전반적인 보조사 사용 빈도와 전체 유형수는 연령이 높아짐에 따라 유의미한 증가 양상을 보였다. 하위기능별 보조사 사용 빈도는 ‘주제, 한정, 첨가, 선택, 높임’에서 연령집단에 따른 유의한 차이를 보였고, 하위 기능별 보조사 유형수는 ‘대조, 한정, 선택, 높임’ 보조사에서 연령집단 간 유의한 차이가 나타났다. 모든 연령집단에서 ‘주제, 첨

Developmental and Educational PsychologyPsychology
15
논문|인용수 5·2022
The Assessment and Outcomes of Crossmatching in Lung Transplantation in Korean Patients
Ha Eun Kim, Young Ho Yang, Hyo Chae Paik, Su Jin Jeong, Song Yee Kim, Moo Suk Park, Jin Gu Lee
SJR Q2Journal of Korean Medical ScienceOA

Positive CDC and T lymphocyte crossmatching results should be considered in the allocation of donor lungs. If unavailable, the result should be considered for postoperative management in lung transplantation.

SurgeryMedicine

대표 연구 분야

SurgeryPulmonary and Respiratory MedicineBiomedical EngineeringMolecular BiologyFood ScienceInformation Systems

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