이해원 교수

The performance of an immuno-analytical system can be assessed in terms of its analytical sensitivity, i.e., the detection limit of an analyte, which is determined by the amount of analyte molecules bound to the capture antibody that has been immobilized onto a solid surface. To increase the number of the binding complexes, we have investigated a site-directed immobilization of an antibody that has the ability to resolve a current problem associated with a random arrangement of the insolubilized

Rotating compensator multichannel spectroscopic ellipsometry has been employed to determine the optical functions of various liquids used in chemistry. We attempted three different measurement configurations: (1) air-liquid interface, (2) prism-liquid interface, and (3) liquid-sample interface. In prism-liquid interface, we found that the prism surface had roughness and it should be considered in analysis for accurate results. In liquid-sample interface, we had much higher reflection, better sen

Nano-crystalline CeO2 was synthesized by the mechanical milling and subsequent heat-treatment from the mixture of Ce(OH)4 as precursor, and NaCl as diluent. The diluent provided diffusion barrier during milling and heat-treatment, which was easily dissolved out by deionized water. The size of crystallite and the strain variance of CeO2 were depended on the temperature and heat-treatment time: increased with the temperature (400~700oC) and time (1~24 hours) increasing, and saturated near at 20nm

We demonstrate a selective vapor-phase deposition of conductive poly(3,4-ethylenedioxythiophene) (PEDOT) thin films on patterned FeCl3. The PEDOT thin films were grown on various substrates by using the vapor-phase polymerization of ethylenedioxythiophene (EDOT) with FeCl3 catalytic layers at 325 K. The selective deposition of the PEDOT thin films using vapor-phase polymerization was accomplished with patterned FeCl3 layers as templates. Microcontact printing was done to prepare patterned FeCl3

Objective: As a part of plan to develop evidence-based treatment guidelines for depression that is more suitable for Korean situation, we investigate the present status and client’s requirements for non-pharmacological treatment of depression in Korean clinical situation.Methods: This study is a descriptive report. Subjects were patients with depression In 12 university hospitals which is located in metropolis in Korea. We analyzed the records from questionnaire about current clinical status and

High purity multiwall carbon nanotubes (MWCNTs) were synthesized by a continuous mass production apparatus using a catalyst vapor deposition method. The continuous mass production apparatus consisted of a moving heater and a gas decomposer, and this continuous mass production apparatus of carbon nanotubes shows the possibility of industrial scale production of carbon nanotubes. The MWNTs have lengths of several micrometres and diameters in the range of 20 to 60 nm with over 90% purity, a straigh

A photoacid generator (PAG) played an important role in withdrawing an electron in atomic force microcopy (AFM) anodization lithography. In case of the silicon substrate coated by the polymer with higher content of PAG, oxide patterns were fabricated in lower threshold lithographic bias. And the oxide patterns were grown bigger on the PAG polymer coated silicon than on bare silicon. These results indicate that PAG contributes to accept electrons sufficient to grow oxide patterns. The organic res

We report on the distribution of mixed self-assembled monolayers (SAMs) composed of biotinylated and diluent alkylthiolates for streptavidin immobilization. Two thiol derivatives, 11-mercapto-1-undecanol (MUOH) and 11-mercaptoundecanoic-(8-biotinylamido-3,6-dioxaoctyl) amide (MBDA), were employed for mixed SAM. These thiols formed self-assembled monolayer without local domain, and streptavidins were immobilized onto biotinylated gold surface without nonspecific binding. In order to find the opti

Single-walled carbon nanotubes (SWCNTs) having high density were synthesized on both Fe-Mo/Si and Fe-Mo/MgO/Si substrates by using thermal decomposition of C2H2 at 800 ℃. By applying an ultraviolet-irradiated-ozone (UV-ozone) treatment to the substrate, high-density catalyst nanoparticles could be attached to not only a Si substrate but also a MgO/Si substrate by using a dipping method. The vertically aligned SWCNTs were successfully synthesized on a MgO/Si substrate after NH3 pretreatment. Scan

An eective 3-D nanostructure for nano-sized devices was designed using single-walled carbon nanotubes (SWNTs) as a main frameof the structure. The NH2 modied polystyrene (PS) nanosphere with an average diameter of 100 nm could form SWNT-PS nanospherecomposite and selective attachment to SWNT distributed on gold template by covalent combination, which were accomplished by using.

Atomic force microscope (AFM)-based anodic oxidation lithography has gained great in¬terests in fabricating nanometer scale features on semiconductor or metal substrates beyond the limitation of optical lithography. In this article AFM anodic oxidation lithography and its organic resist layers are introduced based on our previous works. Organic resist layers of self-assembled monolayers, Langmuir-Blodgett films and polymer films are suggested to play a key role in en¬hancing the aspect ratio of

Three dimensional hierarchical gold electrodes were fabricated using suspended 3D networks of carbon nanotubes (CNTs) on Si pillar templates by electrochemical deposition (ECD) in KAu(CN)<SUB>2</SUB> solution. Pt-coated networks of CNTs played an important role to provide the electrical paths for ECD through discontinuous Pt layer, resulting in vertically uniform deposition of gold on micropillars as well as 3D networks of CNTs which were connecting with adjacent micropillars. Structural charact

Objectives：This study investigated the psychosocial factors and clinical symptoms related to the duration of untreated psychosis (DUP) in 35 consecutive first-episode inpatients with schizophrenia. Methods：Data from 35 schizophrenic patients were obtained from two general psychiatric inpatient units at a university medical center. These data included scores from Index of Social Position (ISP), Positive and Negative Syndrome Scale (PANSS) and Symptom Checklist-90-Revised (SCL-90-R) as well as soc

Objectives: There has been a continued debate regarding the role of eye movements in Eye Movement Desensitization and Reprocessing (EMDR). This study examined the possible autonomic effect of horizontal eye movements after being exposed to fearful stimuli. Methods: Fifty two healthy adult women were randomly allocated to eye movement or eye fixed group after watching a five minute fear-inducing film clip. ECG was recorded during the resting state, watching the clip, and the treatment. A spectral