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고학철 교수

Hak-Chul Ko

경희대학교 신경외과 · 의학

연구실 소개

고학철 교수의 연구실은 뇌신경질환 및 척추신경계 질환의 진단과 치료에 중점을 두고 있으며, 특히 천식성 뇌막염, 경련성 운동장애, 산소공급부족성 뇌병변 등 희귀 신경계 질환의 메커니즘과 치료 전략을 탐구하고 있습니다. 영상유도 수술 및 방사선외과적 치료(예: 감마 Knife)를 포함한 최소침습적 치료법의 장기적 효과와 적용 범위를 분석하며, 뇌신경압박, 혈관성 통증, 뇌척수액 유출 등 복합적 병변의 종합적 접근을 추구하고 있습니다. 특히 뇌신경질환의 영상 소견과 임상 양상 간의 연관성을 깊이 있게 분석함으로써 개인 맞춤형 신경외과 치료 전략을 개발하고 있습니다.

희귀 뇌신경질환최소침습적 수술뇌척수액 유출신경압박장기적 치료 결과

연구 현황

논문 수
48
총 인용 수
288
최근 5년 논문
12
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
12총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
18총합
20212022202320242025

주요 논문

15
1
논문|인용수 59·2018
A Case of Diffuse Leptomeningeal Glioneuronal Tumor Misdiagnosed as Chronic Tuberculous Meningitis without Brain Biopsy
Jung Koo Lee, Hak Cheol Ko, Jin-gyu Choi, Youn Soo Lee, Byung-chul Son
Case Reports in Neurological MedicineOA

Here we report a rare case of diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 62-year-old male patient misdiagnosed as having tuberculous meningitis. Due to its rarity and radiologic findings of leptomeningeal enhancement in the basal cisterns on magnetic resonance imaging (MRI) similar to tuberculous meningitis, DLGNT in this patient was initially diagnosed as communicating hydrocephalus from tuberculous meningitis despite absence of laboratory findings of tuberculosis. The patient's sym

GeneticsMedicine
2
논문|인용수 28·2017
Globus Pallidus Internus Deep Brain Stimulation for Disabling Diabetic Hemiballism/Hemichorea
Byung-chul Son, Jin-gyu Choi, Hak Cheol Ko
Case Reports in Neurological MedicineOA

Unilateral hemichorea/hemiballism (HH) associated with contralateral neuroimaging abnormalities of the basal ganglia, which is characterized by T1 hyperintensity on magnetic resonance imaging (MRI) and is secondary to diabetic nonketotic hyperglycemia, is a rare and unique complication of poorly controlled diabetes mellitus (DM). Although almost all prior reports have documented rapid resolution of HH within days after normalization of blood glucose levels, medically refractory persistent HH has

NeurologyMedicine
3
논문|인용수 25·2018
Intraoperative monitoring of Z-L response (ZLR) and abnormal muscle response (AMR) during microvascular decompression for hemifacial spasm. Interpreting the role of ZLR
Byung-chul Son, Hak Cheol Ko, Jin-gyu Choi
SJR Q1Acta Neurochirurgica
Pathology and Forensic MedicineMedicine
4
논문|인용수 21·2012
Long Term Outcomes of Gamma Knife Radiosurgery for Typical Trigeminal Neuralgia-Minimum 5-Year Follow-Up
Jong Kwon Lee, Hyuk Jai Choi, Hak Cheol Ko, Seok Keun Choi, Young Jin Lim
SJR Q2Journal of Korean Neurosurgical SocietyOA

OBJECTIVE: Gamma knife radiosurgery (GKRS) is the least invasive surgical option for patients with trigeminal neuralgia (TN). However, the indications and long term outcomes of GKRS are still controversial. Additionally, a series with uniform long-term follow-up data for all patients has been lacking. In the present study, the authors analyzed long-term outcomes in a series of patients with TN who underwent a single GKRS treatment followed by a minimum follow-up of 60 months. METHODS: From 1994

Pathology and Forensic MedicineMedicine
5
논문|인용수 16·2019
Hemifacial Spasm Caused by Vascular Compression in the Cisternal Portion of the Facial Nerve: Report of Two Cases with Review of the Literature
Byung-chul Son, Hak Cheol Ko, Jin-gyu Choi
Case Reports in Neurological MedicineOA

Although primary hemifacial spasm (HFS) is mostly related to a vascular compression of the facial nerve at its root exit zone (REZ), its occurrence in association with distal, cisternal portion has been repeatedly reported during the last two decades. We report two patients with typical HFS caused by distal neurovascular compression, in which the spasm was successfully treated with microvascular decompression (MVD). Vascular compression of distal, cisternal portion of the facial nerve was identi

Pathology and Forensic MedicineMedicine
6
논문|인용수 15·2018
Hemifacial Trigeminal Pain Referred from Occipital Neuralgia Due to Compression of the Greater Occipital Nerve by the Occipital Artery
Hak Cheol Ko, Jin-gyu Choi, Byung-chul Son
SJR Q2Journal of Neurological Surgery Part A Central European Neurosurgery

Although pathologic vascular contact between the occipital artery and the greater occipital nerve (GON) at the crossing point in the nuchal subcutaneous layer can cause occipital neuralgia, referred hemifacial trigeminal pain from chronic occipital neuralgia owing to this cause is extremely rare.A 61-year-old female patient with left-sided occipital neuralgia for 4 years presented with a new onset of left-sided hemifacial pain. Decompression of the left GON from pathologic contacts with the occi

Psychiatry and Mental healthMedicine
7
논문|인용수 14·2016
Extended Pneumocephalus after Drainage of Chronic Subdural Hematoma Associated with Intracranial Hypotension : Case Report with Pathophysiologic Consideration
Hee Sup Shin, Seung Hwan Lee, Hak Cheol Ko, Jun Seok Koh
SJR Q2Journal of Korean Neurosurgical SocietyOA

Chronic subdural hematoma (SDH) is a well-known disease entity and is traditionally managed with surgery. However, when associated with spontaneous intracranial hypotension (SIH), the treatment strategy ought to be modified, as classical treatment could lead to unwanted consequences. A 59-year-old man presented with a case of SIH that manifested as a bilateral chronic SDH. He developed fatal extensive pneumocephalus and SDH re-accumulation as a complication of burr-hole drainage. Despite applica

NeurologyMedicine
8
리뷰|인용수 11·2018
Characteristic Signs on T2*-Based Imaging and Their Relationship with Results of Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Evidence to Date
Hak Cheol Ko, Chang‐Woo Ryu, Seong Jong Yun, Jun Seok Koh, Hee Sup Shin, Eui Jong Kim
SJR Q2NeurointerventionOA

Our meta-analysis of the published data showed that a SVS was not a predictive factor for recanalization after reperfusion therapy for acute ischemic stroke. Currently, the data available on T2*MRI are too limited to warrant reperfusion therapy in routine practice. More data are needed from studies with randomized treatment allocation to determine the role of T2*MRI.

EpidemiologyMedicine
9
논문|인용수 8·2018
Chronic unilateral temporo-occipital headache attributed to unilateral C3 radiculopathy
Hak Cheol Ko, Byung-chul Son
Asian Journal of NeurosurgeryOA

Although C1–C3 upper cervical radiculopathy can cause a headache, most case reports are occipital neuralgia (ON), not headache. Here, we report a unique case of chronic temporo-occipital headache due to C3 radiculopathy. A 62-year-old male presented with a chronic left-sided temporo-occipital headache with duration of 4 years. The headache was aching and pressure like in nature. It had a typical radiating pattern on every occasion. It started in the posterior temporal area above the ear. It then

Psychiatry and Mental healthMedicine
10
논문|인용수 8·2021
The clinical outcomes of mechanical thrombectomy for proximal M1 occlusion involving lenticulostriate perforators
Hak Cheol Ko
SJR Q3MedicineOA

ABSTRACT: Although the success rate of recanalization in acute intracranial artery occlusion is high, there is a poor rate of improvement in functional clinical outcome. The purpose of this study was to assess the functional outcome of mechanical thrombectomy for proximal M1 occlusion involving lenticulostriate arteries (LSAs) compared with distal M1 occlusion-sparing the LSAs.A retrospective analysis was conducted in patients with middle cerebral artery (MCA) M1 occlusions who had a successful

EpidemiologyMedicine
11
논문|인용수 8·2018
Progressive multifocal leukoencephalopathy diagnosed by brain biopsy, not by the DNA test for JC Virus
Seung-yoon Lee, Hak Cheol Ko, Sang-Il Kim, Youn Lee, Byung-chul Son
Asian Journal of NeurosurgeryOA

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by a lytic infection of oligodendrocytes due to the presence of JC polyomavirus (JCV). The disease occurs mostly in immunocompromised patients and is associated with a high mortality rate. The diagnosis of PML is based on a polymerase chain reaction (PCR) assay for JC viral DNA in cerebrospinal fluid (CSF). However, case reports of the diagnosis of PML established with brain biopsy de

OncologyMedicine
12
논문|인용수 7·2020
Correlation between gray matter volume loss followed by aneurysmal subarachnoid hemorrhage and subarachnoid hemorrhage volume
Geon Yang Lee, Chang‐Woo Ryu, Hak Cheol Ko, Geon‐Ho Jahng
SJR Q1Neuroradiology
NeurologyMedicine
13
논문|인용수 7·2018
Technical Implications in Revision Surgery for Deep Brain Stimulation (DBS) of the Thalamus for Refractory Epilepsy
Byung-chul Son, Young‐Min Shon, Seonghoon Kim, Ji Yeon Kim, Hak Cheol Ko, Jin-gyu Choi
Journal of Epilepsy ResearchOA

BACKGROUND AND PURPOSE: Implantation of deep brain stimulation (DBS) electrodes in the anterior nucleus of the thalamus (ANT) or the centromedian nucleus (CM), for the treatment of refractory epilepsy, is technically demanding. To enhance the accuracy of electrode placement within the ANT and CM, we analyzed our experience with electrode revision surgery in ANT and CM DBS and investigated the cause of misplacement and verifying methods for accurate placement. METHODS: A retrospective analysis of

NeurologyMedicine
14
논문|인용수 5·2020
Facial Nerve Indentation in Hemifacial Spasm: An Analysis of Factors Contributing to the Formation of and Consequent Effects Associated with Indentation
Hak Cheol Ko, Seung Hwan Lee, Hee Sup Shin
SJR Q2World Neurosurgery
Pathology and Forensic MedicineMedicine
15
논문|인용수 3·2020
Predicting Arachnoid Membrane Descent in the Chiasmatic Cistern in the Treatment of Pituitary Macroadenoma
Hak Cheol Ko, Seung Hwan Lee, Hee Sup Shin, Jun Seok Koh
SJR Q2Journal of Korean Neurosurgical SocietyOA

OBJECTIVE: Preoperative prediction of the arachnoid membrane descent in pituitary surgery is useful for achieving gross total removal and avoiding cerebrospinal fluid leakage resulting from tearing of the arachnoid membrane in the chiasmatic cistern. In this study, we analyzed the patterns of arachnoid membrane descent during or after pituitary tumor surgery and identified the factors related to this descent. METHODS: Analysis was restricted to pituitary macroadenomas not extending into the thir

Endocrinology, Diabetes and MetabolismMedicine

대표 연구 분야

NeurologyPathology and Forensic MedicinePsychiatry and Mental healthSurgeryRadiology, Nuclear Medicine and ImagingEpidemiology

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