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이학영 교수

Hak-Young Lee

경희대학교 신경과 · 의학

연구실 소개

이학영 교수의 연구실은 신경과학과 산업보건의 융합 분야에서 활동하며, 주로 뇌신경계 질환, 특히 알츠하이머병 및 인지장애와 관련된 생체지표 탐색과 신경영상 기반의 병변 분석을 중심으로 연구를 진행하고 있습니다. 특히 도파민성 신경전달물질 기능 이상, 갈망성 기억장애 환자에서의 약물 유발 인지장애, 그리고 중금속 노출에 의한 신경학적 손상 메커니즘 등 신경생물학적 기전과 임상적 결과 간의 연관성을 규명하고자 합니다. 또한, 정신건강과 신경퇴행성 질환 간의 상호작용을 고려한 종합적 접근을 통해 조기 진단 및 예방 전략 개발에 기여하고자 합니다.

신경영상인지장애알츠하이머병중금속 독성약물유발 혼란

연구 현황

논문 수
133
총 인용 수
1,224
최근 5년 논문
47
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
47총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
235총합
20222023202420252026

주요 논문

15
1
논문|인용수 34·2009
Recurrent ischemic stroke in a patient with idiopathic thrombocytopenic purpura
Hak Young Rhee, Hye‐Yeon Choi, Jong‐Min Kim, Won Chul Shin
SJR Q2Journal of Thrombosis and Thrombolysis
HematologyMedicine
2
논문|인용수 11·2013
Prevalence of Musculoskeletal Disorders Among Korean Police Personnel
Hak Young Rhee, Jae-Hwan Cho, Jong Min Seok, Taek Sang Cho, Woo Jin Jeon, Jin Gu Lee, Sung Kyu Kim
SJR Q2Archives of Environmental & Occupational Health

This study was conducted to investigate efficient, systematic management of the Korean police and to examine the status and prevention of musculoskeletal disorders in Korean police officers. For police officers in special working environments, the importance of basic data is emphasized for human resources (HR) management and the prevention of industrial hazards from an industrial health care perspective. This study was conducted on police officers who visited the national police hospital and who

Occupational TherapyHealth Professions
3
논문|인용수 11·2010
Paraganglioma of the filum terminale presenting with normal pressure hydrocephalus
Hak Young Rhee, Dae Jean Jo, Jun‐Hwan Lee, Sung Hun Kim
SJR Q2Clinical Neurology and Neurosurgery
Cellular and Molecular NeuroscienceNeuroscience
4
논문|인용수 7·2010
Acute Ischemic Stroke in a Patient with a Native Valvular Strand
Hak Young Rhee, Hye‐Yeon Choi, Jong‐Min Kim, Won Chul Shin, Sung Hun Kim
SJR Q4Case Reports in NeurologyOA

Valvular strands are known to be a potential source of cardioembolism but the natural history of native valvular strands has not yet been fully outlined. We report a case of ischemic stroke in a patient with a native valvular strand of the aortic valve and the patient's clinical course. A previously healthy 21-year-old man suffered acute cerebral infarction in the right posterior cerebral artery territory. On echocardiography, there was a strand-like, oscillating mass on the left coronary cusp o

Cardiology and Cardiovascular MedicineMedicine
5
논문|인용수 6·2020
Interactive Effects of Apolipoprotein E ε4 and Triiodothyronine on Memory Performance in Patients With Subjective Cognitive Decline
Jin San Lee, Yunsoo Soh, Hyug‐Gi Kim, Kyung Mi Lee, Young Nam Kwon, Sung Sang Yoon, Key‐Chung Park, Hak Young Rhee
SJR Q1Frontiers in MedicineOA

<b>Background:</b> The aim of the present study was to investigate the associations between thyroid hormones, cognitive performance, and apolipoprotein E (<i>APOE</i>) genotype in euthyroid patients with subjective cognitive decline (SCD). <b>Methods:</b> We recruited 197 euthyroid patients that fulfilled the criteria for SCD. All participants were classified into <i>APOE</i> ε4 carriers and non-carriers based on the presence of the <i>APOE</i> ε4 allele. Patients with SCD who had the <i>APOE</i

Endocrinology, Diabetes and MetabolismMedicine
6
논문|인용수 3·2010
Cerebral Air Embolism as a Result of Inducing Pneumoperitoneum After Bilobectomy
Hak Young Rhee, Dae‐Hyun Kim, Young Tae Kwak, Jae Woo Lee, Sung Hun Kim
SJR Q1The Annals of Thoracic SurgeryOA
Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 3·2002
A Case of Mercury Intoxication Presenting Cerebellar Ataxia.
Hak Young Rhee, Mi‐Sook Lee, Sung-Sang Yoon, Te-Gyu Lee, Dae‐Il Chang, Kyung-Cheon Chung
Journal of the Korean Neurological Association

Mercury poisoning affects various organs including peripheral and central nervous systems, especially cerebellum. We report a case of mercury intoxication presenting cerebellar ataxia. From several days after exposure to mercury vapor, scanning speech, head titubation, bilateral limb and truncal ataxia developed and progressed slowly. On admission, brain MRI did not show remarkable change. However, nine months later, atrophic changes in both cerebellar hemispheres on follow-up brain MRI and perf

Health, Toxicology and MutagenesisEnvironmental Science
8
논문|인용수 2·2021
Delirium caused by topical administration of cyclopentolate for cataract surgery in mild cognitive impairment due to Alzheimer's disease
Yu Yong Shin, Jin San Lee, Key‐Chung Park, Hak Young Rhee
SJR Q3MedicineOA

RATIONALES: Cholinergic modification by anticholinergic medication can produce adverse effects in central nervous system (CNS) and cyclopentolate is an antimuscarinic agent widely used for ophthalmologic management. We demonstrate a rare case of hyperactive delirium caused by topical administration of cyclopentolate in a patient with amnestic mild cognitive impairment (MCI) due to Alzheimer's disease (AD). PATIENT CONCERNS: A 74-year-old man showed acute confusion after preparation for cataract

Critical Care and Intensive Care MedicineMedicine
9
논문|인용수 2·2002
소뇌실조증을 보인 수은중독 1예
이학영, 이미숙, 윤성상, 이태규, 장대일, 정경천
10
논문|인용수 1·2010
P2‐389: Quantification of intrinsic brain iron using diffusion tensor imaging in patients with Alzheimer's disease
Hak Young Rhee, Songfan Xu, Geon‐Ho Jahng, M. W. Weiner, Norbert Schuff
SJR Q1Alzheimer s & Dementia

DT MRI involves the application of external diffusion-sensitizing magnetic field gradients. In addition, there may be local susceptibility-induced background gradients, related to intrinsic magnetic properties of brain tissue. Paramagnetic iron-containing amyloid plaques in AD may induce local background gradients, interfering with diffusion measurements in the brain. The objective of our study was to map the distribution of local cross-term gradients between the external and internal gradients

Radiology, Nuclear Medicine and ImagingMedicine
11
letter|인용수 1·2018
Amyloid-positive late-onset semantic variant primary progressive aphasia
Jin San Lee, Hak Young Rhee, Key‐Chung Park
SJR Q1Neurological Sciences
NeurologyMedicine
12
논문|인용수 0·2023
Hyperintensity on Diffusion‐Weighted MRI and Clinical Correlations in Probable Creutzfeldt‐Jakob Disease
Hak Young Rhee, Key‐Chung Park
SJR Q1Alzheimer s & DementiaOA

Abstract Background Although definite diagnosis for Creutzfeldt‐Jakob disease(CJD) requires tissue confirmation, diffusion‐weighted imaging (DWI) of the brain has an important role in the diagnosis of CJD. Also elevated CSF total tau (t‐tau) is considered as an useful CJD biomarker revealing neuro‐axonal damage although it is not specific for CJD. In this study, we attempted to find out the association between DWI abnormality and CSF t‐tau in CJD patients. Method We retrospectively analyzed the

Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
논문|인용수 0·2019
Molecular imaging of Alzheimer's disease dementia by chemical exchange saturation transfer MRI
Hak Young Rhee, K.C. Park
SJR Q1Journal of the Neurological Sciences
Materials ChemistryMaterials Science
14
논문|인용수 0·2015
P1‐203: Impact of ApoE‐ε4 on white matter microstructure in patients with Alzheimer's disease
Hak Young Rhee, Geon‐Ho Jahng, Key‐Chung Park, Ji Hoon Lee, Ho Geol Woo
SJR Q1Alzheimer s & Dementia

It has been reported that pathological white matter changes develops in at least 50% of patients with AD. Diffusion tensor imaging (DTI) studies revealed a pattern of reduced fractional anisotropy (FA) and increased mean diffusivity in AD patients compared with healthy controls, indicating white matter deterioration. The effect of APOE ε4 on WM integrity in AD patients is incongruous. The aim of this study is to find the effect of APOE ε4 on WM integrity in AD patients using DTI. A total of 25 p

Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 0·2025
Investigating Brain‐Kidney Connection: Effect on Cerebral Blood Flow with Different Levels of Estimated Glomerular Filtration Rate in Normal Brains
Hak Young Rhee, Geon‐Ho Jahng, Jin Yong Lee
SJR Q1Alzheimer s & DementiaOA

BACKGROUND: Cerebral blood flow (CBF) plays a pivotal role in maintaining brain function and metabolism, serving as a crucial parameter for assessing brain health. Similarly, the estimated glomerular filtration rate (eGFR) measures kidney function and determines kidney disease stages. CBF and eGFR assess the vascular health of two essential organs-the brain and the kidney. METHOD: We enrolled 785 healthy middle-aged and older adults undergoing regular health check-ups at our Health Promotion Cen

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

NeurologyPsychiatry and Mental healthRadiology, Nuclear Medicine and ImagingPhysiologyPulmonary and Respiratory MedicineCognitive Neuroscience

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