한동우 교수

BACKGROUND: Radiation pneumonitis is one of the most harmful and clinically significant complications of radiotherapy. This study investigated the benefits of nebulized acetylcysteine for lung cancer patients diagnosed with radiation pneumonitis after radiotherapy. METHODS: We prospectively enrolled and followed 25 patients with radiation pneumonitis who used nebulized acetylcysteine three times a day for 12 weeks. We also reviewed the medical records of 106 control patients who had undergone ra

Smoking patients with diabetes mellitus (DM) are at greater risk of developing pneumonia. How smoking behavior changes affect the risk of pneumonia hospitalization, however, remains unclear. Therefore, we investigated the association between smoking behavior change and the risk of pneumonia hospitalization in patients with DM. From January 1, 2009 and December 31, 2018, we investigated the association between smoking behavior change and the risk of pneumonia hospitalization in patients with DM.

BACKGROUND: Limited data exist on idiopathic pulmonary fibrosis (IPF) incidence and risk factors in elderly populations, making early intervention and preventive strategies challenging. Further research is needed to address this gap and improve outcomes. OBJECTIVES: This study used the Korean National Health Insurance Service (NHIS) database to investigate factors associated with the development of IPF in elderly people. DESIGN: A retrospective cohort study was conducted to evaluate risk factors

In this paper, we reframed the Lady-Bandit-Guard problem from the perspective of the defender, focusing on strategies to protect the Lady from an approaching Bandit and simulating these strategies using the Kerbal Space Program (KSP) game engine. The problem is divided into two zones based on the distance between the Lady and the Bandit: the Warning Zone and the Dead Zone. In the Warning Zone, the Guard positions itself between the Lady and the Bandit to perform surveillance through formation fl

In this paper, we address the consideration of designing satellite constellations for Earth and celestial bodies like the Moon and Mars, where the influence of complex perturbations complicates orbit prediction. Traditionally, long-term simulations have been employed to calculate performance metrics such as coverage, resulting in a significant computational load due to the large amount of data generated. A common approach to reduce this has been to compute performance over one orbital period and

<b>Rationale:</b> Smoking patients with diabetes mellitus (DM) are at greater risk of developing pneumonia. How smoking behavior changes affect the risk of pneumonia hospitalization, however, remains unclear. <b>Methods:</b> From 2009 and to 2018, we investigated the association between smoking change and the risk of pneumonia hospitalization in patients with DM. A total of 332,798 adult patients with DM from the Korean National Health Insurance System database who underwent health screening exa

<bold>Backgrounds:</bold> Idiopathic pulmonary fibrosis (IPF) is chronic progressive fibrosing interstitial lung disease with dismal prognosis. Acute exacerbation (AE) of IPF, has been known to impact significantly on prognosis. However, underlying mechanisms and effective treatments for AE remain poorly understood. <bold>Methods:</bold> Bronchoalveolar lavage fluid (BAL) samples were consecutively collected from IPF patients with or without AE (each number = 3). Single-cell RNA sequencing was p

<bold>Background:</bold> Although lung cancer screening using low-dose computed tomography (CT) reduces lung cancer specific mortality, the high false-positive rate highlights the need for complementary diagnostic tools. We evaluated a protein signature classifier using aptamer technology and Luminex assay as diagnostic aid for lung nodule. <bold>Methods:</bold> This retrospective study was conducted in Asan Medical Center, a tertiary referral center in South Korea, including patients with more

BACKGROUND: The coronavirus disease 2019 (COVID-19) vaccination is suggested to be effective in improving outcomes of chronic obstructive pulmonary disease (COPD). However, real-world evidence on long-term mortality among individuals with COPD, accounting for both vaccination and COVID-19 infection status, remains sparse. METHODS: A retrospective cohort study was conducted using datasets from the Korean National Health Insurance system. Through two-step propensity score matching, 716 individuals