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Lymphangiogenesis and lymphatic vessel remodeling are complex biological processes frequently observed during inflammation. Accumulating evidence indicates that inflammation-associated lymphangiogenesis (IAL) is not merely an endpoint event, but actually a phenomenon actively involved in the pathophysiology of various inflammatory disorders. The VEGF-C/VEGFR-3 and VEGF-A/VEGF-R2 signaling pathways are two of the best-studied pathways in IAL. Methods targeting these molecules, such as prolymphang

Preoperative MR imaging in rectal cancer patients for staging with conventional 2D and multiplanar reconstruction 3D T2-weighted imaging protocols showed no significant differences in accuracy of T and N category staging and overall image quality, as determined by degree of artifact. However, the 3D T2-weighted imaging protocol had limitations in regard to lesion conspicuity.

Rectal submucosal lesions encompass a wide variety of benign and malignant tumors involving the rectum. With optical colonoscopy, any mass-like protrusion covered by normal mucosa, whether the underlying process is intramural or extramural in origin, may be reported as a submucosal lesion. Whereas the assessment of submucosal lesions may be limited with performing optical colonoscopy, cross-sectional imaging such as CT, transrectal ultrasonography and MRI allows the evaluation of perirectal tiss

SLN mapping with fluorescent iodized oil emulsion is effective and feasible for both CT and NIR imaging.

Histogram analysis of hepatobiliary phase images of gadoxetic acid-enhanced MRI can provide non-invasive quantitative measurements of hepatic fibrosis.

PURPOSE: The risk of hepatocellular carcinoma (HCC) recurrence must be considered ahead of surgery. This study was undertaken to identify pre-operative risk factors for early intrahepatic recurrence of HCC after curative resection in a large-scale. MATERIALS AND METHODS: We retrospectively reviewed the preoperative three-phase multi-detector CT (MDCT) and laboratory data for 240 HCC patients who underwent curative resection; tumor size, number, gross shape, capsule integrity, distinctiveness of

In this issue of Blood , Scholz et al have demonstrated that the expression of angiopoietin-2 (Ang2) in the endothelial cells is sufficient to recruit myeloid cells and induce inflammation even in the absence of preceding proinflammatory stimuli.[1][1] This finding shows that the endothelial cells

// Honsoul Kim 1,2 , Song-Ee Baek 1,2 , Jieun Moon 3 , Yun Ho Roh 3 , Narae Lee 4 and Arthur Cho 4 1 Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea 2 Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea 3 Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea 4 Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea Co

Positive mrMRF and mrEMVI status was associated with a higher risk of post-operative tumor relapse of pCR achieved by rectal cancer patients, and therefore, can be applied for risk stratification and to individualize treatment plans.

The circulatory system of mammals consists of 2 compo-nents, blood vessels and lymphatic vessels, which are counterparts that act in parallel but develop in series. Unlike blood vessels that are a system built up to form a closed circuit carrying circulating blood, lymphatic vessels differ in that it is an open system with unique architecture starting at its periphery as a blunt end specialized to drain excessive interstitial fluid. Lymphatic vessel function is not merely confined to the drainag