김희은 교수
Hee Eun Kim
서울대학교 응급의학과 · 의학
연구실 소개
김희은 교수의 연구실은 뇌영상학과 세포기반 치료를 융합한 신경영상 및 줄기세포 치료 분야에서 주목받는 연구를 수행하고 있습니다. 특히 갑상선암 환자에서 림프절 전이의 정밀 진단을 위한 초음파 기반 영상 분석과, 뇌혈관 질환에서의 MRI/MRA를 활용한 질환 구별 기법 개발에 주력하고 있으며, 신경정신의학 분야에서는 불안장애 환자의 세로토닌 수용체 기능 변화를 정량화하는 PET 영상 기법을 개발하여 치료 반응 예측에 기여하고자 합니다. 또한, 지방줄기세포를 활용한 다양한 세포치료 전략 개발을 통해 체내에서 쉽게 확보 가능하면서도 다방향 분화 능력을 지닌 ADSC의 임상적 응용 가능성을 탐색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The US/CT combination was found to be superior to US alone for the detection of metastatic lymph nodes in the lateral neck levels in PTC patients by level-by-level analysis.
Brain lesions were typically located at the cerebellar dentate nucleus, midbrain, dorsal pons, medulla, and splenium of the corpus callosum. According to DWI, most of the lesions in MIE probably corresponded to areas of vasogenic edema, whereas only some of them, located in the corpus callosum, corresponded to cytotoxic edema.
Adult stem cells have a great potential to treat various diseases. For these cell-based therapies, adipose-derived stem cells (ADSCs) are one of the most promising stem cell types, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). ESCs and iPSCs have taken center stage due to their pluripotency. However, ESCs and iPSCs have limitations in ethical issues and in identification of characteristics, respectively. Unlike ESCs and iPSCs, ADSCs do not have such limitation
JVR and cavernous DAVF can be differentiated from one another using MRI and MRA.
Asymptomatic subjects may have fat in RV on CT. However, these subjects show no RV dysfunction or significant ECG-abnormalities consistent with the diagnosis of arrhythmogenic RV dysplasia.
BACKGROUND: Obsessive-compulsive disorder (OCD) is a chronic, relapsing mental illness. Selective serotonin reuptake inhibitors block serotonin transporters (SERTs) and are the mainstay of treatment for OCD. SERT abnormalities are reported in drug-free patients with OCD, but it is not known what happens to SERT levels during treatment. This is important as alterations in SERT levels in patients under treatment could underlie poor response, or relapse during or after treatment. The aim of the pre
AuNPs of 50 nm in size can regulate melanoma cells in kilovoltage X-ray treatment by functioning as dose-enhancement agent and thus improving radioresponse of the cells. Melanomas of stages T1-T3 gain therapeutic benefits from 150 kVp X-ray treatment.
Mean transit time is the most predictive parameter for assessing decreased CVR in patients with unilateral steno-occlusive vascular disease.
Abstract Introduction: The near-universal genetic amplification events at 9p24.1 in classic Hodgkin lymphoma (cHL) results in overexpression of the programmed death 1 (PD-1) ligands and betrays an unusual dependence on the PD-1 pathway. Inhibition of this pathway by use of pembrolizumab has shown effective antitumor activity and acceptable safety in patients with relapsed or refractory cHL (R/RcHL) in the multicohort KEYNOTE-087 study. This led to FDA approval of pembrolizumab for the treatment
Computed tomography is more sensitive and accurate than PET-CT for detecting metastatic lymph nodes in recurrent PTC. No significant relationship was found between the CT features and the PET-CT findings of the metastatic nodes.
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